RAMP3 (receptor activity modifying protein 3)

2011-03-01  

Identity

HGNC
LOCATION
7p13
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 10268
MIM: 605155
HGNC: 9845
Ensembl: ENSG00000122679

Variants:

dbSNP: 10268
ClinVar: 10268
TCGA: ENSG00000122679
COSMIC: RAMP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000122679ENST00000242249O60896
ENSG00000122679ENST00000242249A4D2L1
ENSG00000122679ENST00000481345O60896
ENSG00000122679ENST00000481345A4D2L1
ENSG00000122679ENST00000496212J3KR56

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Vascular smooth muscle contractionKEGGhsa04270
Vascular smooth muscle contractionKEGGko04270
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class B/2 (Secretin family receptors)REACTOMER-HSA-373080
Calcitonin-like ligand receptorsREACTOMER-HSA-419812
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (s) signalling eventsREACTOMER-HSA-418555

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
119734352002Immunohistochemical localization of calcitonin receptor-like receptor and receptor activity-modifying proteins in the human cerebral vasculature.33
156134682005Novel function for receptor activity-modifying proteins (RAMPs) in post-endocytic receptor trafficking.29
198866712009Molecular basis of association of receptor activity-modifying protein 3 with the family B G protein-coupled secretin receptor.22
185938222008Identification of N-terminal receptor activity-modifying protein residues important for calcitonin gene-related peptide, adrenomedullin, and amylin receptor function.20
158051082005Receptor activity-modifying protein (RAMP) isoform-specific regulation of adrenomedullin receptor trafficking by NHERF-1.18
270136572016Receptor Activity-modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties.18
241996272014Receptor activity-modifying protein-dependent effects of mutations in the calcitonin receptor-like receptor: implications for adrenomedullin and calcitonin gene-related peptide pharmacology.15
169122192006A critical role for the short intracellular C terminus in receptor activity-modifying protein function.13
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11

Citation

Dessen P

RAMP3 (receptor activity modifying protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2011-03-01

Online version: http://atlasgeneticsoncology.org/gene/52142/ramp3