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RAP2C (RAP2C, member of RAS oncogene family)

Identity

Alias_symbol (synonym)DKFZp313B211
Other alias-
HGNC (Hugo) RAP2C
LocusID (NCBI) 57826
Atlas_Id 42044
Location Xq26.2  [Link to chromosome band Xq26]
Location_base_pair Starts at 131337052 and ends at 131353508 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
RAP2C (Xq26.2) / RAP2C (Xq26.2)SLIRP (14q24.3) / RAP2C (Xq26.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RAP2C   21165
Cards
Entrez_Gene (NCBI)RAP2C  57826  RAP2C, member of RAS oncogene family
Aliases
GeneCards (Weizmann)RAP2C
Ensembl hg19 (Hinxton)ENSG00000123728 [Gene_View]  chrX:131337052-131353508 [Contig_View]  RAP2C [Vega]
Ensembl hg38 (Hinxton)ENSG00000123728 [Gene_View]  chrX:131337052-131353508 [Contig_View]  RAP2C [Vega]
ICGC DataPortalENSG00000123728
TCGA cBioPortalRAP2C
AceView (NCBI)RAP2C
Genatlas (Paris)RAP2C
WikiGenes57826
SOURCE (Princeton)RAP2C
Genetics Home Reference (NIH)RAP2C
Genomic and cartography
GoldenPath hg19 (UCSC)RAP2C  -     chrX:131337052-131353508 -  Xq26.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RAP2C  -     Xq26.2   [Description]    (hg38-Dec_2013)
EnsemblRAP2C - Xq26.2 [CytoView hg19]  RAP2C - Xq26.2 [CytoView hg38]
Mapping of homologs : NCBIRAP2C [Mapview hg19]  RAP2C [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK124801 AK310997 AL049685 AL832461 AY298955
RefSeq transcript (Entrez)NM_001271186 NM_001271187 NM_021183
RefSeq genomic (Entrez)NC_000023 NC_018934 NT_011786 NW_004929446
Consensus coding sequences : CCDS (NCBI)RAP2C
Cluster EST : UnigeneHs.743556 [ NCBI ]
CGAP (NCI)Hs.743556
Alternative Splicing GalleryENSG00000123728
Gene ExpressionRAP2C [ NCBI-GEO ]   RAP2C [ EBI - ARRAY_EXPRESS ]   RAP2C [ SEEK ]   RAP2C [ MEM ]
Gene Expression Viewer (FireBrowse)RAP2C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57826
GTEX Portal (Tissue expression)RAP2C
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y3L5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y3L5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y3L5
Splice isoforms : SwissVarQ9Y3L5
PhosPhoSitePlusQ9Y3L5
Domaine pattern : Prosite (Expaxy)RAS (PS51421)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase    Small_GTPase_Ras   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Domain families : Smart (EMBL)RAS (SM00173)  
Conserved Domain (NCBI)RAP2C
DMDM Disease mutations57826
Blocks (Seattle)RAP2C
SuperfamilyQ9Y3L5
Human Protein AtlasENSG00000123728
Peptide AtlasQ9Y3L5
HPRD06706
IPIIPI00009607   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y3L5
IntAct (EBI)Q9Y3L5
FunCoupENSG00000123728
BioGRIDRAP2C
STRING (EMBL)RAP2C
ZODIACRAP2C
Ontologies - Pathways
QuickGOQ9Y3L5
Ontology : AmiGOtranscription coactivator activity  GTP binding  cytoplasm  cytosol  plasma membrane  bicellular tight junction  protein transport  GDP binding  microvillus assembly  negative regulation of cell migration  positive regulation of protein autophosphorylation  Rap protein signal transduction  cell-cell contact zone  recycling endosome membrane  regulation of protein tyrosine kinase activity  extracellular exosome  establishment of endothelial intestinal barrier  establishment of endothelial intestinal barrier  regulation of nucleic acid-templated transcription  
Ontology : EGO-EBItranscription coactivator activity  GTP binding  cytoplasm  cytosol  plasma membrane  bicellular tight junction  protein transport  GDP binding  microvillus assembly  negative regulation of cell migration  positive regulation of protein autophosphorylation  Rap protein signal transduction  cell-cell contact zone  recycling endosome membrane  regulation of protein tyrosine kinase activity  extracellular exosome  establishment of endothelial intestinal barrier  establishment of endothelial intestinal barrier  regulation of nucleic acid-templated transcription  
NDEx NetworkRAP2C
Atlas of Cancer Signalling NetworkRAP2C
Wikipedia pathwaysRAP2C
Orthology - Evolution
OrthoDB57826
GeneTree (enSembl)ENSG00000123728
Phylogenetic Trees/Animal Genes : TreeFamRAP2C
HOVERGENQ9Y3L5
HOGENOMQ9Y3L5
Homologs : HomoloGeneRAP2C
Homology/Alignments : Family Browser (UCSC)RAP2C
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRAP2C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RAP2C
dbVarRAP2C
ClinVarRAP2C
1000_GenomesRAP2C 
Exome Variant ServerRAP2C
ExAC (Exome Aggregation Consortium)RAP2C (select the gene name)
Genetic variants : HAPMAP57826
Genomic Variants (DGV)RAP2C [DGVbeta]
DECIPHER (Syndromes)X:131337052-131353508  ENSG00000123728
CONAN: Copy Number AnalysisRAP2C 
Mutations
ICGC Data PortalRAP2C 
TCGA Data PortalRAP2C 
Broad Tumor PortalRAP2C
OASIS PortalRAP2C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRAP2C  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRAP2C
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RAP2C
DgiDB (Drug Gene Interaction Database)RAP2C
DoCM (Curated mutations)RAP2C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RAP2C (select a term)
intoGenRAP2C
Cancer3DRAP2C(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenRAP2C
Genetic Testing Registry RAP2C
NextProtQ9Y3L5 [Medical]
TSGene57826
GENETestsRAP2C
Huge Navigator RAP2C [HugePedia]
snp3D : Map Gene to Disease57826
BioCentury BCIQRAP2C
ClinGenRAP2C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57826
Chemical/Pharm GKB GenePA134899238
Clinical trialRAP2C
Miscellaneous
canSAR (ICR)RAP2C (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRAP2C
EVEXRAP2C
GoPubMedRAP2C
iHOPRAP2C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:16:53 CEST 2017

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