Identity
HGNC
LOCATION
2q33.2
LOCUSID
ALIAS
ALS2CR18,ALS2CR9,LPD,PREL-2,PREL2,RMO1,RalGDS/AF-6
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 65059
MIM: 609035
HGNC: 14436
Ensembl: ENSG00000173166
Variants:
dbSNP: 65059
ClinVar: 65059
TCGA: ENSG00000173166
COSMIC: RAPH1
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38062011 | 2023 | Nuclear isoform of RAPH1 interacts with FOXQ1 to promote aggressiveness and radioresistance in breast cancer. | 0 |
| 38062011 | 2023 | Nuclear isoform of RAPH1 interacts with FOXQ1 to promote aggressiveness and radioresistance in breast cancer. | 0 |
| 30056565 | 2018 | Clinicopathological and prognostic significance of Ras association and pleckstrin homology domains 1 (RAPH1) in breast cancer. | 6 |
| 30056565 | 2018 | Clinicopathological and prognostic significance of Ras association and pleckstrin homology domains 1 (RAPH1) in breast cancer. | 6 |
| 26726010 | 2016 | Mechanistic insights into the phosphatidylinositol binding properties of the pleckstrin homology domain of lamellipodin. | 3 |
| 27346732 | 2016 | Association between RAPH1 Gene Haplotypes and CHE2 Locus Phenotypes. | 2 |
| 26726010 | 2016 | Mechanistic insights into the phosphatidylinositol binding properties of the pleckstrin homology domain of lamellipodin. | 3 |
| 27346732 | 2016 | Association between RAPH1 Gene Haplotypes and CHE2 Locus Phenotypes. | 2 |
| 26169271 | 2015 | Lamellipodin Is Important for Cell-to-Cell Spread and Actin-Based Motility in Listeria monocytogenes. | 14 |
| 26295568 | 2015 | Lamellipodin promotes actin assembly by clustering Ena/VASP proteins and tethering them to actin filaments. | 44 |
| 26419705 | 2015 | A RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migration. | 48 |
| 26169271 | 2015 | Lamellipodin Is Important for Cell-to-Cell Spread and Actin-Based Motility in Listeria monocytogenes. | 14 |
| 26295568 | 2015 | Lamellipodin promotes actin assembly by clustering Ena/VASP proteins and tethering them to actin filaments. | 44 |
| 26419705 | 2015 | A RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migration. | 48 |
| 23483482 | 2013 | Crystal structure of Lamellipodin implicates diverse functions in actin polymerization and Ras signaling. | 13 |
Citation
Dessen P
RAPH1 (Ras association (RalGDS/AF-6) and pleckstrin homology domains 1)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43448/raph1
