Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

RAPH1 (Ras association (RalGDS/AF-6) and pleckstrin homology domains 1)

Identity

Alias_namescandidate 18
ALS2CR9
ALS2CR18
Alias_symbol (synonym)KIAA1681
Other aliasLPD
PREL-2
PREL2
RMO1
RalGDS/AF-6
HGNC (Hugo) RAPH1
LocusID (NCBI) 65059
Atlas_Id 43448
Location 2q33.2  [Link to chromosome band 2q33]
Location_base_pair Starts at 203441469 and ends at 203535336 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NRBF2 (10q21.3) / RAPH1 (2q33.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RAPH1   14436
Cards
Entrez_Gene (NCBI)RAPH1  65059  Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
AliasesALS2CR18; ALS2CR9; LPD; PREL-2; 
PREL2; RMO1; RalGDS/AF-6
GeneCards (Weizmann)RAPH1
Ensembl hg19 (Hinxton)ENSG00000173166 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173166 [Gene_View]  chr2:203441469-203535336 [Contig_View]  RAPH1 [Vega]
ICGC DataPortalENSG00000173166
TCGA cBioPortalRAPH1
AceView (NCBI)RAPH1
Genatlas (Paris)RAPH1
WikiGenes65059
SOURCE (Princeton)RAPH1
Genetics Home Reference (NIH)RAPH1
Genomic and cartography
GoldenPath hg38 (UCSC)RAPH1  -     chr2:203441469-203535336 -  2q33.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RAPH1  -     2q33.2   [Description]    (hg19-Feb_2009)
EnsemblRAPH1 - 2q33.2 [CytoView hg19]  RAPH1 - 2q33.2 [CytoView hg38]
Mapping of homologs : NCBIRAPH1 [Mapview hg19]  RAPH1 [Mapview hg38]
OMIM609035   
Gene and transcription
Genbank (Entrez)AB051468 AB053311 AB053320 AF086189 AI217860
RefSeq transcript (Entrez)NM_001329728 NM_025252 NM_203365 NM_213589
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RAPH1
Cluster EST : UnigeneHs.471162 [ NCBI ]
CGAP (NCI)Hs.471162
Alternative Splicing GalleryENSG00000173166
Gene ExpressionRAPH1 [ NCBI-GEO ]   RAPH1 [ EBI - ARRAY_EXPRESS ]   RAPH1 [ SEEK ]   RAPH1 [ MEM ]
Gene Expression Viewer (FireBrowse)RAPH1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)65059
GTEX Portal (Tissue expression)RAPH1
Human Protein AtlasENSG00000173166-RAPH1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ70E73   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ70E73  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ70E73
Splice isoforms : SwissVarQ70E73
PhosPhoSitePlusQ70E73
Domaine pattern : Prosite (Expaxy)PH_DOMAIN (PS50003)    RA (PS50200)   
Domains : Interpro (EBI)PH_dom-like    PH_domain    RA_dom    Ubiquitin-rel_dom   
Domain families : Pfam (Sanger)PH (PF00169)    RA (PF00788)   
Domain families : Pfam (NCBI)pfam00169    pfam00788   
Domain families : Smart (EMBL)PH (SM00233)  RA (SM00314)  
Conserved Domain (NCBI)RAPH1
DMDM Disease mutations65059
Blocks (Seattle)RAPH1
PDB (SRS)4GMV    4GN1   
PDB (PDBSum)4GMV    4GN1   
PDB (IMB)4GMV    4GN1   
PDB (RSDB)4GMV    4GN1   
Structural Biology KnowledgeBase4GMV    4GN1   
SCOP (Structural Classification of Proteins)4GMV    4GN1   
CATH (Classification of proteins structures)4GMV    4GN1   
SuperfamilyQ70E73
Human Protein Atlas [tissue]ENSG00000173166-RAPH1 [tissue]
Peptide AtlasQ70E73
HPRD12356
IPIIPI00871620   IPI00656016   IPI00656058   IPI00655621   IPI00743280   IPI00656088   IPI00655588   IPI00655897   IPI00402234   IPI00396531   IPI00978265   IPI00927778   IPI00926192   IPI01025889   IPI00924780   
Protein Interaction databases
DIP (DOE-UCLA)Q70E73
IntAct (EBI)Q70E73
FunCoupENSG00000173166
BioGRIDRAPH1
STRING (EMBL)RAPH1
ZODIACRAPH1
Ontologies - Pathways
QuickGOQ70E73
Ontology : AmiGOprotein binding  cytosol  cytoskeleton  plasma membrane  signal transduction  nuclear body  lamellipodium  filopodium  axon extension  
Ontology : EGO-EBIprotein binding  cytosol  cytoskeleton  plasma membrane  signal transduction  nuclear body  lamellipodium  filopodium  axon extension  
NDEx NetworkRAPH1
Atlas of Cancer Signalling NetworkRAPH1
Wikipedia pathwaysRAPH1
Orthology - Evolution
OrthoDB65059
GeneTree (enSembl)ENSG00000173166
Phylogenetic Trees/Animal Genes : TreeFamRAPH1
HOVERGENQ70E73
HOGENOMQ70E73
Homologs : HomoloGeneRAPH1
Homology/Alignments : Family Browser (UCSC)RAPH1
Gene fusions - Rearrangements
Tumor Fusion PortalRAPH1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRAPH1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RAPH1
dbVarRAPH1
ClinVarRAPH1
1000_GenomesRAPH1 
Exome Variant ServerRAPH1
ExAC (Exome Aggregation Consortium)ENSG00000173166
GNOMAD BrowserENSG00000173166
Genetic variants : HAPMAP65059
Genomic Variants (DGV)RAPH1 [DGVbeta]
DECIPHERRAPH1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRAPH1 
Mutations
ICGC Data PortalRAPH1 
TCGA Data PortalRAPH1 
Broad Tumor PortalRAPH1
OASIS PortalRAPH1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRAPH1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRAPH1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RAPH1
DgiDB (Drug Gene Interaction Database)RAPH1
DoCM (Curated mutations)RAPH1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RAPH1 (select a term)
intoGenRAPH1
Cancer3DRAPH1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609035   
Orphanet
DisGeNETRAPH1
MedgenRAPH1
Genetic Testing Registry RAPH1
NextProtQ70E73 [Medical]
TSGene65059
GENETestsRAPH1
Target ValidationRAPH1
Huge Navigator RAPH1 [HugePedia]
snp3D : Map Gene to Disease65059
BioCentury BCIQRAPH1
ClinGenRAPH1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD65059
Chemical/Pharm GKB GenePA24749
Clinical trialRAPH1
Miscellaneous
canSAR (ICR)RAPH1 (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRAPH1
EVEXRAPH1
GoPubMedRAPH1
iHOPRAPH1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:31:45 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.