Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5916
MIM: 180190
HGNC: 9866
Ensembl: ENSG00000172819
Variants:
dbSNP: 5916
ClinVar: 5916
TCGA: ENSG00000172819
COSMIC: RARG
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA130620651 | anthracyclines and related substances | Chemical | ClinicalAnnotation | associated | PD | ||
| PA166128121 | cardiotoxicity | Disease | ClinicalAnnotation | associated | PD | ||
| PA445062 | Neoplasms | Disease | ClinicalAnnotation | associated | PD | ||
| PA449212 | daunorubicin | Chemical | GuidelineAnnotation | associated | |||
| PA449412 | doxorubicin | Chemical | GuidelineAnnotation | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37828659 | 2024 | The Role of RARG rs2229774, SLC28A3 rs7853758, and UGT1A6*4 rs17863783 Single-nucleotide Polymorphisms in the Doxorubicin-induced Cardiotoxicity in Solid Childhood Tumors. | 0 |
| 38245869 | 2024 | Histone lactylation inhibits RARγ expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling. | 3 |
| 37828659 | 2024 | The Role of RARG rs2229774, SLC28A3 rs7853758, and UGT1A6*4 rs17863783 Single-nucleotide Polymorphisms in the Doxorubicin-induced Cardiotoxicity in Solid Childhood Tumors. | 0 |
| 38245869 | 2024 | Histone lactylation inhibits RARγ expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling. | 3 |
| 36183362 | 2023 | Retinoic acid receptor gamma is required for proliferation of pancreatic cancer cells. | 3 |
| 37897947 | 2023 | RARγ promotes the invasion and metastasis of thyroid carcinoma by activating the JAK1-STAT3-CD24/MMPs axis. | 0 |
| 36183362 | 2023 | Retinoic acid receptor gamma is required for proliferation of pancreatic cancer cells. | 3 |
| 37897947 | 2023 | RARγ promotes the invasion and metastasis of thyroid carcinoma by activating the JAK1-STAT3-CD24/MMPs axis. | 0 |
| 34470463 | 2021 | Polymorphisms in Vitamin A-Related Genes and Their Functions in Autoimmune Thyroid Disease. | 1 |
| 34470463 | 2021 | Polymorphisms in Vitamin A-Related Genes and Their Functions in Autoimmune Thyroid Disease. | 1 |
| 32587261 | 2020 | Variation in RARG increases susceptibility to doxorubicin-induced cardiotoxicity in patient specific induced pluripotent stem cell-derived cardiomyocytes. | 23 |
| 33252195 | 2020 | Temporal activation of LRH-1 and RAR-γ in human pluripotent stem cells induces a functional naïve-like state. | 8 |
| 32587261 | 2020 | Variation in RARG increases susceptibility to doxorubicin-induced cardiotoxicity in patient specific induced pluripotent stem cell-derived cardiomyocytes. | 23 |
| 33252195 | 2020 | Temporal activation of LRH-1 and RAR-γ in human pluripotent stem cells induces a functional naïve-like state. | 8 |
| 30120411 | 2019 | The miR-96 and RARγ signaling axis governs androgen signaling and prostate cancer progression. | 28 |
Citation
Dessen P
RARG (retinoic acid receptor gamma)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/42049/rarg
