| Nomenclature |
|---|
| HGNC (Hugo) | RARG 9866 |
| Cards |
|---|
| Entrez_Gene (NCBI) | RARG 5916 retinoic acid receptor gamma |
| Aliases | NR1B3; RARC |
| GeneCards (Weizmann) | RARG |
| Ensembl hg19 (Hinxton) | ENSG00000172819 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000172819 [Gene_View] ENSG00000172819 [Sequence] chr12:53210566-53220413 [Contig_View] RARG [Vega] |
| ICGC DataPortal | ENSG00000172819 |
| TCGA cBioPortal | RARG |
| AceView (NCBI) | RARG |
| Genatlas (Paris) | RARG |
| WikiGenes | 5916 |
| SOURCE (Princeton) | RARG |
| Genetics Home Reference (NIH) | RARG |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | RARG - chr12:53210566-53220413 - 3p24.2 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | RARG - 3p24.2 [Description] (hg19-Feb_2009) |
| Ensembl | RARG - 3p24.2 [CytoView hg19] RARG - 3p24.2 [CytoView hg38] |
| Mapping of homologs : NCBI | RARG [Mapview hg19] RARG [Mapview hg38] |
| OMIM | 180190 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AB307689 AK290588 AK297023 AK297110 AK297277 |
| RefSeq transcript (Entrez) | NM_000966 NM_001042728 NM_001243730 NM_001243731 NM_001243732 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | RARG |
| Cluster EST : Unigene | Hs.733399 [ NCBI ] |
| CGAP (NCI) | Hs.733399 |
| Alternative Splicing Gallery | ENSG00000172819 |
| Gene Expression | RARG [ NCBI-GEO ] RARG [ EBI - ARRAY_EXPRESS ]
RARG [ SEEK ] RARG [ MEM ] |
| Gene Expression Viewer (FireBrowse) | RARG [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 5916 |
| GTEX Portal (Tissue expression) | RARG |
| Human Protein Atlas | ENSG00000172819-RARG [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P13631 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P13631 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P13631 |
| Splice isoforms : SwissVar | P13631 |
| PhosPhoSitePlus | P13631 |
| Domaine pattern : Prosite (Expaxy) | NR_LBD (PS51843) NUCLEAR_REC_DBD_1 (PS00031) NUCLEAR_REC_DBD_2 (PS51030) |
| Domains : Interpro (EBI) | NHR_like_dom_sf Nucl_hrmn_rcpt_lig-bd Nuclear_hrmn_rcpt Retinoic_acid_rcpt Znf_hrmn_rcpt Znf_NHR/GATA |
| Domain families : Pfam (Sanger) | Hormone_recep (PF00104) zf-C4 (PF00105) |
| Domain families : Pfam (NCBI) | pfam00104 pfam00105 |
| Domain families : Smart (EMBL) | HOLI (SM00430) ZnF_C4 (SM00399) |
| Conserved Domain (NCBI) | RARG |
| DMDM Disease mutations | 5916 |
| Blocks (Seattle) | RARG |
| PDB (SRS) | 1EXA 1EXX 1FCX 1FCY 1FCZ 1FD0 2LBD 3LBD 4LBD 5M24 |
| PDB (PDBSum) | 1EXA 1EXX 1FCX 1FCY 1FCZ 1FD0 2LBD 3LBD 4LBD 5M24 |
| PDB (IMB) | 1EXA 1EXX 1FCX 1FCY 1FCZ 1FD0 2LBD 3LBD 4LBD 5M24 |
| PDB (RSDB) | 1EXA 1EXX 1FCX 1FCY 1FCZ 1FD0 2LBD 3LBD 4LBD 5M24 |
| Structural Biology KnowledgeBase | 1EXA 1EXX 1FCX 1FCY 1FCZ 1FD0 2LBD 3LBD 4LBD 5M24 |
| SCOP (Structural Classification of Proteins) | 1EXA 1EXX 1FCX 1FCY 1FCZ 1FD0 2LBD 3LBD 4LBD 5M24 |
| CATH (Classification of proteins structures) | 1EXA 1EXX 1FCX 1FCY 1FCZ 1FD0 2LBD 3LBD 4LBD 5M24 |
| Superfamily | P13631 |
| Human Protein Atlas [tissue] | ENSG00000172819-RARG [tissue] |
| Peptide Atlas | P13631 |
| HPRD | 01573 |
| IPI | IPI00465344 IPI00427809 IPI00788710 IPI01020715 IPI01016077 IPI00921806 IPI00984457 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P13631 |
| IntAct (EBI) | P13631 |
| FunCoup | ENSG00000172819 |
| BioGRID | RARG |
| STRING (EMBL) | RARG |
| ZODIAC | RARG |
| Ontologies - Pathways |
|---|
| QuickGO | P13631 |
| Ontology : AmiGO | negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II nuclear chromatin transcription regulatory region sequence-specific DNA binding RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding neural tube closure liver development glandular epithelial cell development retinal pigment epithelium development growth plate cartilage chondrocyte growth DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity steroid hormone receptor activity retinoic acid receptor activity retinoic acid receptor activity nuclear receptor activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm transcription factor complex transcription initiation from RNA polymerase II promoter multicellular organism development brain development heart development transcription factor binding zinc ion binding positive regulation of cell proliferation negative regulation of cell proliferation regulation of cell size hormone-mediated signaling pathway anterior/posterior pattern specification integral component of membrane cell differentiation nuclear receptor transcription coactivator activity epithelial cell differentiation embryonic camera-type eye development regulation of myelination negative regulation of chondrocyte differentiation response to retinoic acid response to retinoic acid response to lipid embryonic hindlimb morphogenesis multicellular organism growth positive regulation of apoptotic process negative regulation of apoptotic process positive regulation of programmed cell death steroid hormone mediated signaling pathway regulation of myeloid cell differentiation positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II retinoid X receptor binding embryonic eye morphogenesis retinoic acid receptor signaling pathway retinoic acid receptor signaling pathway embryonic organ development gland development canonical Wnt signaling pathway face development bone morphogenesis epithelium development trachea cartilage development prostate gland epithelium morphogenesis Harderian gland development cellular response to retinoic acid cellular response to retinoic acid RNA polymerase II transcription factor complex transcription factor activity, direct ligand regulated sequence-specific DNA binding cellular response to leukemia inhibitory factor |
| Ontology : EGO-EBI | negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II nuclear chromatin transcription regulatory region sequence-specific DNA binding RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding neural tube closure liver development glandular epithelial cell development retinal pigment epithelium development growth plate cartilage chondrocyte growth DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity steroid hormone receptor activity retinoic acid receptor activity retinoic acid receptor activity nuclear receptor activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm transcription factor complex transcription initiation from RNA polymerase II promoter multicellular organism development brain development heart development transcription factor binding zinc ion binding positive regulation of cell proliferation negative regulation of cell proliferation regulation of cell size hormone-mediated signaling pathway anterior/posterior pattern specification integral component of membrane cell differentiation nuclear receptor transcription coactivator activity epithelial cell differentiation embryonic camera-type eye development regulation of myelination negative regulation of chondrocyte differentiation response to retinoic acid response to retinoic acid response to lipid embryonic hindlimb morphogenesis multicellular organism growth positive regulation of apoptotic process negative regulation of apoptotic process positive regulation of programmed cell death steroid hormone mediated signaling pathway regulation of myeloid cell differentiation positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II retinoid X receptor binding embryonic eye morphogenesis retinoic acid receptor signaling pathway retinoic acid receptor signaling pathway embryonic organ development gland development canonical Wnt signaling pathway face development bone morphogenesis epithelium development trachea cartilage development prostate gland epithelium morphogenesis Harderian gland development cellular response to retinoic acid cellular response to retinoic acid RNA polymerase II transcription factor complex transcription factor activity, direct ligand regulated sequence-specific DNA binding cellular response to leukemia inhibitory factor |
| NDEx Network | RARG |
| Atlas of Cancer Signalling Network | RARG |
| Wikipedia pathways | RARG |
| Orthology - Evolution |
|---|
| OrthoDB | 5916 |
| GeneTree (enSembl) | ENSG00000172819 |
| Phylogenetic Trees/Animal Genes : TreeFam | RARG |
| HOVERGEN | P13631 |
| HOGENOM | P13631 |
| Homologs : HomoloGene | RARG |
| Homology/Alignments : Family Browser (UCSC) | RARG |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | NUP98/RARG [11p15.4/12q13.13] [t(11;12)(p15;q13)] |
| Fusion : Mitelman | RARG/BCAS1 [12q13.13/20q13.2] [t(12;20)(q13;q13)] |
| Fusion Portal | RARG 12q13.13 BCAS1 20q13.2 BLCA |
| Fusion : Quiver | RARG |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | RARG [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | RARG |
| dbVar | RARG |
| ClinVar | RARG |
| 1000_Genomes | RARG |
| Exome Variant Server | RARG |
| ExAC (Exome Aggregation Consortium) | ENSG00000172819 |
| GNOMAD Browser | ENSG00000172819 |
| Varsome Browser | RARG |
| Genetic variants : HAPMAP | 5916 |
| Genomic Variants (DGV) | RARG [DGVbeta] |
| DECIPHER | RARG [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | RARG |
| Mutations |
|---|
| ICGC Data Portal | RARG |
| TCGA Data Portal | RARG |
| Broad Tumor Portal | RARG |
| OASIS Portal | RARG [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | RARG [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | RARG |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search RARG |
| DgiDB (Drug Gene Interaction Database) | RARG |
| DoCM (Curated mutations) | RARG (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | RARG (select a term) |
| intoGen | RARG |
| Cancer3D | RARG(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 180190 |
| Orphanet | |
| DisGeNET | RARG |
| Medgen | RARG |
| Genetic Testing Registry | RARG
|
| NextProt | P13631 [Medical] |
| TSGene | 5916 |
| GENETests | RARG |
| Target Validation | RARG |
| Huge Navigator |
RARG [HugePedia] |
| snp3D : Map Gene to Disease | 5916 |
| BioCentury BCIQ | RARG |
| ClinGen | RARG |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 5916 |
| Chemical/Pharm GKB Gene | PA34227 |
| Clinical trial | RARG |
| Miscellaneous |
|---|
| canSAR (ICR) | RARG (select the gene name) |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 91 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | RARG |
| EVEX | RARG |
| GoPubMed | RARG |
| iHOP | RARG |
