RASD1 (ras related dexamethasone induced 1)

2003-02-01  

Identity

HGNC
LOCATION
17p11.2
LOCUSID
ALIAS
AGS1,DEXRAS1,MGC:26290
FUSION GENES

Other Information

Locus ID:

NCBI: 51655
MIM: 605550
HGNC: 15828
Ensembl: ENSG00000108551

Variants:

dbSNP: 51655
ClinVar: 51655
TCGA: ENSG00000108551
COSMIC: RASD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000108551ENST00000225688Q9Y272
ENSG00000108551ENST00000579152Q9Y272

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
500

Pathways

PathwaySourceExternal ID
Circadian entrainmentKEGGhsa04713
Circadian entrainmentKEGGko04713

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
151848692004The Ras-related protein AGS1/RASD1 suppresses cell growth.37
171670882006The molecular gatekeeper Dexras1 sculpts the photic responsiveness of the mammalian circadian clock.24
195497722009Genomic screening for genes silenced by DNA methylation revealed an association between RASD1 inactivation and dexamethasone resistance in multiple myeloma.24
189227982008Dexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcription.21
128184262003Identification of a glucocorticoid response element in the 3'-flanking region of the human Dexras1 gene.9
164891242006Dexamethasone-induced Ras protein 1 negatively regulates protein kinase C delta: implications for adenylyl cyclase 2 signaling.9
247619102014Up-regulating of RASD1 and apoptosis of DU-145 human prostate cancer cells induced by formononetin in vitro.9
286005282017Overexpression of RASD1 inhibits glioma cell migration/invasion and inactivates the AKT/mTOR signaling pathway.8
297220682018Differential ability of formononetin to stimulate proliferation of endothelial cells and breast cancer cells via a feedback loop involving MicroRNA-375, RASD1, and ERα.7
212474192011Rasd1 interacts with Ear2 (Nr2f6) to regulate renin transcription.6

Citation

Dessen P

RASD1 (ras related dexamethasone induced 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42055/rasd1