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RASEF (RAS and EF-hand domain containing)

Identity

Alias_namesRAB45
RAB45
Alias_symbol (synonym)FLJ31614
Other alias
HGNC (Hugo) RASEF
LocusID (NCBI) 158158
Atlas_Id 41998
Location 9q21.32  [Link to chromosome band 9q21]
Location_base_pair Starts at 85594500 and ends at 85678043 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ENSA (1q21.3) / RASEF (9q21.32)NTRK2 (9q21.33) / RASEF (9q21.32)RASEF (9q21.32) / OSTF1 (9q21.13)
ZSWIM1 (20q13.12) / RASEF (9q21.32)NTRK2 9q21.33 / RASEF 9q21.32RASEF 9q21.32 / OSTF1 9q21.13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RASEF   26464
Cards
Entrez_Gene (NCBI)RASEF  158158  RAS and EF-hand domain containing
AliasesRAB45
GeneCards (Weizmann)RASEF
Ensembl hg19 (Hinxton)ENSG00000165105 [Gene_View]  chr9:85594500-85678043 [Contig_View]  RASEF [Vega]
Ensembl hg38 (Hinxton)ENSG00000165105 [Gene_View]  chr9:85594500-85678043 [Contig_View]  RASEF [Vega]
ICGC DataPortalENSG00000165105
TCGA cBioPortalRASEF
AceView (NCBI)RASEF
Genatlas (Paris)RASEF
WikiGenes158158
SOURCE (Princeton)RASEF
Genetics Home Reference (NIH)RASEF
Genomic and cartography
GoldenPath hg19 (UCSC)RASEF  -     chr9:85594500-85678043 -  9q21.32   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RASEF  -     9q21.32   [Description]    (hg38-Dec_2013)
EnsemblRASEF - 9q21.32 [CytoView hg19]  RASEF - 9q21.32 [CytoView hg38]
Mapping of homologs : NCBIRASEF [Mapview hg19]  RASEF [Mapview hg38]
OMIM611344   
Gene and transcription
Genbank (Entrez)AK056176 AK056882 AK057300 AK290986 BC023566
RefSeq transcript (Entrez)NM_152573
RefSeq genomic (Entrez)NC_000009 NC_018920 NT_008470 NW_004929366
Consensus coding sequences : CCDS (NCBI)RASEF
Cluster EST : UnigeneHs.677846 [ NCBI ]
CGAP (NCI)Hs.677846
Alternative Splicing GalleryENSG00000165105
Gene ExpressionRASEF [ NCBI-GEO ]   RASEF [ EBI - ARRAY_EXPRESS ]   RASEF [ SEEK ]   RASEF [ MEM ]
Gene Expression Viewer (FireBrowse)RASEF [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)158158
GTEX Portal (Tissue expression)RASEF
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IZ41   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IZ41  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IZ41
Splice isoforms : SwissVarQ8IZ41
PhosPhoSitePlusQ8IZ41
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)    RAB (PS51419)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom    P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase    Small_GTPase_Rab_type   
Domain families : Pfam (Sanger)EF-hand_7 (PF13499)    Ras (PF00071)   
Domain families : Pfam (NCBI)pfam13499    pfam00071   
Domain families : Smart (EMBL)EFh (SM00054)  RAB (SM00175)  
Conserved Domain (NCBI)RASEF
DMDM Disease mutations158158
Blocks (Seattle)RASEF
PDB (SRS)2P5S    2PMY   
PDB (PDBSum)2P5S    2PMY   
PDB (IMB)2P5S    2PMY   
PDB (RSDB)2P5S    2PMY   
Structural Biology KnowledgeBase2P5S    2PMY   
SCOP (Structural Classification of Proteins)2P5S    2PMY   
CATH (Classification of proteins structures)2P5S    2PMY   
SuperfamilyQ8IZ41
Human Protein AtlasENSG00000165105
Peptide AtlasQ8IZ41
HPRD08337
IPIIPI00412443   IPI00043268   
Protein Interaction databases
DIP (DOE-UCLA)Q8IZ41
IntAct (EBI)Q8IZ41
FunCoupENSG00000165105
BioGRIDRASEF
STRING (EMBL)RASEF
ZODIACRASEF
Ontologies - Pathways
QuickGOQ8IZ41
Ontology : AmiGOGTPase activity  calcium ion binding  GTP binding  intracellular protein transport  nucleocytoplasmic transport  small GTPase mediated signal transduction  metabolic process  membrane  perinuclear region of cytoplasm  
Ontology : EGO-EBIGTPase activity  calcium ion binding  GTP binding  intracellular protein transport  nucleocytoplasmic transport  small GTPase mediated signal transduction  metabolic process  membrane  perinuclear region of cytoplasm  
NDEx NetworkRASEF
Atlas of Cancer Signalling NetworkRASEF
Wikipedia pathwaysRASEF
Orthology - Evolution
OrthoDB158158
GeneTree (enSembl)ENSG00000165105
Phylogenetic Trees/Animal Genes : TreeFamRASEF
HOVERGENQ8IZ41
HOGENOMQ8IZ41
Homologs : HomoloGeneRASEF
Homology/Alignments : Family Browser (UCSC)RASEF
Gene fusions - Rearrangements
Fusion : MitelmanNTRK2/RASEF [9q21.33/9q21.32]  [t(9;9)(q21;q21)]  
Fusion : MitelmanRASEF/OSTF1 [9q21.32/9q21.13]  [t(9;9)(q21;q21)]  
Fusion: TCGANTRK2 9q21.33 RASEF 9q21.32 BRCA
Fusion: TCGARASEF 9q21.32 OSTF1 9q21.13 PRAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRASEF [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RASEF
dbVarRASEF
ClinVarRASEF
1000_GenomesRASEF 
Exome Variant ServerRASEF
ExAC (Exome Aggregation Consortium)RASEF (select the gene name)
Genetic variants : HAPMAP158158
Genomic Variants (DGV)RASEF [DGVbeta]
DECIPHER (Syndromes)9:85594500-85678043  ENSG00000165105
CONAN: Copy Number AnalysisRASEF 
Mutations
ICGC Data PortalRASEF 
TCGA Data PortalRASEF 
Broad Tumor PortalRASEF
OASIS PortalRASEF [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRASEF  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRASEF
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RASEF
DgiDB (Drug Gene Interaction Database)RASEF
DoCM (Curated mutations)RASEF (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RASEF (select a term)
intoGenRASEF
Cancer3DRASEF(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611344   
Orphanet
MedgenRASEF
Genetic Testing Registry RASEF
NextProtQ8IZ41 [Medical]
TSGene158158
GENETestsRASEF
Huge Navigator RASEF [HugePedia]
snp3D : Map Gene to Disease158158
BioCentury BCIQRASEF
ClinGenRASEF
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD158158
Chemical/Pharm GKB GenePA134867201
Clinical trialRASEF
Miscellaneous
canSAR (ICR)RASEF (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRASEF
EVEXRASEF
GoPubMedRASEF
iHOPRASEF
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:16:57 CEST 2017

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