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RASGEF1C (RasGEF domain family member 1C)

Identity

Alias_symbol (synonym)FLJ35841
Other alias-
HGNC (Hugo) RASGEF1C
LocusID (NCBI) 255426
Atlas_Id 43452
Location 5q35.3  [Link to chromosome band 5q35]
Location_base_pair Starts at 180100795 and ends at 180209130 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
RNF130 (5q35.3) / RASGEF1C (5q35.3)SLC12A7 (5p15.33) / RASGEF1C (5q35.3)RNF130 5q35.3 / RASGEF1C 5q35.3
SLC12A7 5p15.33 / RASGEF1C 5q35.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RASGEF1C   27400
Cards
Entrez_Gene (NCBI)RASGEF1C  255426  RasGEF domain family member 1C
Aliases
GeneCards (Weizmann)RASGEF1C
Ensembl hg19 (Hinxton)ENSG00000146090 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000146090 [Gene_View]  chr5:180100795-180209130 [Contig_View]  RASGEF1C [Vega]
ICGC DataPortalENSG00000146090
TCGA cBioPortalRASGEF1C
AceView (NCBI)RASGEF1C
Genatlas (Paris)RASGEF1C
WikiGenes255426
SOURCE (Princeton)RASGEF1C
Genetics Home Reference (NIH)RASGEF1C
Genomic and cartography
GoldenPath hg38 (UCSC)RASGEF1C  -     chr5:180100795-180209130 -  5q35.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RASGEF1C  -     5q35.3   [Description]    (hg19-Feb_2009)
EnsemblRASGEF1C - 5q35.3 [CytoView hg19]  RASGEF1C - 5q35.3 [CytoView hg38]
Mapping of homologs : NCBIRASGEF1C [Mapview hg19]  RASGEF1C [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF449764 AK093160 BC036802 BC057759 BF967301
RefSeq transcript (Entrez)NM_001031799 NM_175062
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RASGEF1C
Cluster EST : UnigeneHs.190559 [ NCBI ]
CGAP (NCI)Hs.190559
Alternative Splicing GalleryENSG00000146090
Gene ExpressionRASGEF1C [ NCBI-GEO ]   RASGEF1C [ EBI - ARRAY_EXPRESS ]   RASGEF1C [ SEEK ]   RASGEF1C [ MEM ]
Gene Expression Viewer (FireBrowse)RASGEF1C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)255426
GTEX Portal (Tissue expression)RASGEF1C
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N431   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N431  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N431
Splice isoforms : SwissVarQ8N431
PhosPhoSitePlusQ8N431
Domaine pattern : Prosite (Expaxy)RASGEF (PS00720)    RASGEF_CAT (PS50009)    RASGEF_NTER (PS50212)   
Domains : Interpro (EBI)Ras-like_Gua-exchang_fac_N    Ras_G-nucl-exch_fac_CS    Ras_GEF_dom    RASGEF_cat_dom   
Domain families : Pfam (Sanger)RasGEF (PF00617)    RasGEF_N (PF00618)   
Domain families : Pfam (NCBI)pfam00617    pfam00618   
Domain families : Smart (EMBL)RasGEF (SM00147)  
Conserved Domain (NCBI)RASGEF1C
DMDM Disease mutations255426
Blocks (Seattle)RASGEF1C
SuperfamilyQ8N431
Human Protein AtlasENSG00000146090
Peptide AtlasQ8N431
HPRD15212
IPIIPI00300415   IPI00413049   IPI00978877   
Protein Interaction databases
DIP (DOE-UCLA)Q8N431
IntAct (EBI)Q8N431
FunCoupENSG00000146090
BioGRIDRASGEF1C
STRING (EMBL)RASGEF1C
ZODIACRASGEF1C
Ontologies - Pathways
QuickGOQ8N431
Ontology : AmiGOguanyl-nucleotide exchange factor activity  intracellular  small GTPase mediated signal transduction  positive regulation of GTPase activity  
Ontology : EGO-EBIguanyl-nucleotide exchange factor activity  intracellular  small GTPase mediated signal transduction  positive regulation of GTPase activity  
NDEx NetworkRASGEF1C
Atlas of Cancer Signalling NetworkRASGEF1C
Wikipedia pathwaysRASGEF1C
Orthology - Evolution
OrthoDB255426
GeneTree (enSembl)ENSG00000146090
Phylogenetic Trees/Animal Genes : TreeFamRASGEF1C
HOVERGENQ8N431
HOGENOMQ8N431
Homologs : HomoloGeneRASGEF1C
Homology/Alignments : Family Browser (UCSC)RASGEF1C
Gene fusions - Rearrangements
Fusion : MitelmanRNF130/RASGEF1C [5q35.3/5q35.3]  [t(5;5)(q35;q35)]  
Fusion : MitelmanSLC12A7/RASGEF1C [5p15.33/5q35.3]  [t(5;5)(p15;q35)]  
Fusion: TCGARNF130 5q35.3 RASGEF1C 5q35.3 LUAD
Fusion: TCGASLC12A7 5p15.33 RASGEF1C 5q35.3 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRASGEF1C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RASGEF1C
dbVarRASGEF1C
ClinVarRASGEF1C
1000_GenomesRASGEF1C 
Exome Variant ServerRASGEF1C
ExAC (Exome Aggregation Consortium)RASGEF1C (select the gene name)
Genetic variants : HAPMAP255426
Genomic Variants (DGV)RASGEF1C [DGVbeta]
DECIPHERRASGEF1C [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRASGEF1C 
Mutations
ICGC Data PortalRASGEF1C 
TCGA Data PortalRASGEF1C 
Broad Tumor PortalRASGEF1C
OASIS PortalRASGEF1C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRASGEF1C  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRASGEF1C
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RASGEF1C
DgiDB (Drug Gene Interaction Database)RASGEF1C
DoCM (Curated mutations)RASGEF1C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RASGEF1C (select a term)
intoGenRASGEF1C
Cancer3DRASGEF1C(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenRASGEF1C
Genetic Testing Registry RASGEF1C
NextProtQ8N431 [Medical]
TSGene255426
GENETestsRASGEF1C
Target ValidationRASGEF1C
Huge Navigator RASGEF1C [HugePedia]
snp3D : Map Gene to Disease255426
BioCentury BCIQRASGEF1C
ClinGenRASGEF1C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD255426
Chemical/Pharm GKB GenePA134895897
Clinical trialRASGEF1C
Miscellaneous
canSAR (ICR)RASGEF1C (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRASGEF1C
EVEXRASGEF1C
GoPubMedRASGEF1C
iHOPRASGEF1C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:28:09 CEST 2017

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