RASGRP1 (RAS guanyl releasing protein 1 (calcium and DAG-regulated))

Identity

Other names	CALDAG-GEFI
	CALDAG-GEFII
	MGC129998
	MGC129999
	RASGRP
	V
	hRasGRP1
HGNC	RASGRP1
Location	15q15
Location_base_pair	Starts at 36567594 and ends at 36644299 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	RASGRP1   9878
Entrez_Gene	RASGRP1  10125  RAS guanyl releasing protein 1 (calcium and DAG-regulated)
	Cards
GeneCards	RASGRP1
Ensembl	RASGRP1 [Search_View]   ENSG00000122644 [Gene_View]
Genatlas	RASGRP1
GeneLynx	RASGRP1
eGenome	RASGRP1
euGene	10125
	Genomic and cartography
GoldenPath	RASGRP1  -  15q15   chr15:36567594-36644299 -  15q14   [Description]    (hg18-March_2006)
Ensembl	RASGRP1 - 15q14 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	RASGRP1
	Gene and transcription
Genbank	AA742351 [ ENTREZ ]
Genbank	AB208848 [ ENTREZ ]
Genbank	AF081195 [ ENTREZ ]
Genbank	AF081197 [ ENTREZ ]
Genbank	AF106071 [ ENTREZ ]
RefSeq	NM_001128602 [ SRS ]    NM_001128602 [ ENTREZ ]
RefSeq	NM_005739 [ SRS ]    NM_005739 [ ENTREZ ]
RefSeq	AC_000058 [ SRS ]    AC_000058 [ ENTREZ ]
RefSeq	AC_000147 [ SRS ]    AC_000147 [ ENTREZ ]
RefSeq	NC_000015 [ SRS ]    NC_000015 [ ENTREZ ]
RefSeq	NT_010194 [ SRS ]    NT_010194 [ ENTREZ ]
RefSeq	NW_001838214 [ SRS ]    NW_001838214 [ ENTREZ ]
RefSeq	NW_925840 [ SRS ]    NW_925840 [ ENTREZ ]
AceView	RASGRP1 AceView - NCBI
Unigene	Hs.591127 [ SRS ]    Hs.591127 [ NCBI ]     HS591127 [ spliceNest ]
Fast-db	1943 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O95267 [ SRS]    O95267 [ EXPASY ]     O95267 [ INTERPRO ]     O95267 [ UNIPROT ]
Prosite	PS00018 EF_HAND_1 [ SRS ]    PS00018 EF_HAND_1 [ Expasy ]
Prosite	PS50222 EF_HAND_2 [ SRS ]    PS50222 EF_HAND_2 [ Expasy ]
Prosite	PS00720 RASGEF [ SRS ]    PS00720 RASGEF [ Expasy ]
Prosite	PS50009 RASGEF_CAT [ SRS ]    PS50009 RASGEF_CAT [ Expasy ]
Prosite	PS50212 RASGEF_NTER [ SRS ]    PS50212 RASGEF_NTER [ Expasy ]
Prosite	PS00479 ZF_DAG_PE_1 [ SRS ]    PS00479 ZF_DAG_PE_1 [ Expasy ]
Prosite	PS50081 ZF_DAG_PE_2 [ SRS ]    PS50081 ZF_DAG_PE_2 [ Expasy ]
Interpro	IPR002219 DAG_PE_bd [ SRS ]    IPR002219 DAG_PE_bd [ EBI ]
Interpro	IPR011992 EF-Hand_type [ SRS ]    IPR011992 EF-Hand_type [ EBI ]
Interpro	IPR002048 EF_hand_Ca_bd [ SRS ]    IPR002048 EF_hand_Ca_bd [ EBI ]
Interpro	IPR008937 Ras_GEF [ SRS ]    IPR008937 Ras_GEF [ EBI ]
Interpro	IPR000651 RasGef_N [ SRS ]    IPR000651 RasGef_N [ EBI ]
Interpro	IPR001895 RasGRF_CDC25 [ SRS ]    IPR001895 RasGRF_CDC25 [ EBI ]
CluSTr	O95267
Pfam	PF00130 C1_1 [ SRS ]    PF00130 C1_1 [ Sanger ]    pfam00130 [ NCBI-CDD ]
Pfam	PF00036 efhand [ SRS ]    PF00036 efhand [ Sanger ]    pfam00036 [ NCBI-CDD ]
Pfam	PF00617 RasGEF [ SRS ]    PF00617 RasGEF [ Sanger ]    pfam00617 [ NCBI-CDD ]
Pfam	PF00618 RasGEF_N [ SRS ]    PF00618 RasGEF_N [ Sanger ]    pfam00618 [ NCBI-CDD ]
Smart	SM00109 C1 [EMBL]
Smart	SM00147 RasGEF [EMBL]
Smart	SM00229 RasGEFN [EMBL]
Blocks	O95267
HPRD	04909
	Protein Interaction databases
DIP	O95267
IntAct	O95267
	Polymorphism : SNP, mutations, diseases
OMIM	603962    [ map ]
GENECLINICS	603962
SNP	RASGRP1 [dbSNP-NCBI]
SNP	NM_001128602 [SNP-NCI]
SNP	NM_005739 [SNP-NCI]
SNP	RASGRP1 [GeneSNPs - Utah]  RASGRP1] [HGBASE - SRS]
HAPMAP	RASGRP1 [HAPMAP]
COSMIC	RASGRP1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	RASGRP1
	General knowledge
Family Browser	RASGRP1 [UCSC Family Browser]
SOURCE	NM_001128602
SOURCE	NM_005739
SMD	Hs.591127
SAGE	Hs.591127
GO	Golgi membrane [Amigo]  Golgi membrane
GO	guanyl-nucleotide exchange factor activity [Amigo]  guanyl-nucleotide exchange factor activity
GO	calcium ion binding [Amigo]  calcium ion binding
GO	protein binding [Amigo]  protein binding
GO	intracellular [Amigo]  intracellular
GO	membrane fraction [Amigo]  membrane fraction
GO	cytoplasm [Amigo]  cytoplasm
GO	endoplasmic reticulum [Amigo]  endoplasmic reticulum
GO	endoplasmic reticulum membrane [Amigo]  endoplasmic reticulum membrane
GO	Golgi apparatus [Amigo]  Golgi apparatus
GO	plasma membrane [Amigo]  plasma membrane
GO	Ras protein signal transduction [Amigo]  Ras protein signal transduction
GO	zinc ion binding [Amigo]  zinc ion binding
GO	diacylglycerol binding [Amigo]  diacylglycerol binding
GO	cell differentiation [Amigo]  cell differentiation
GO	regulation of small GTPase mediated signal transduction [Amigo]  regulation of small GTPase mediated signal transduction
KEGG	MAPK signaling pathway
KEGG	T cell receptor signaling pathway
PubGene	RASGRP1
TreeFam	RASGRP1
CTD	10125 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	RASGRP1 Related clones (RZPD - Berlin)
	PubMed
PubMed	16 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Tue Oct 14 20:51:41 2008