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RASSF4 (Ras association domain family member 4)

Identity

Alias (NCBI)AD037
HGNC (Hugo) RASSF4
HGNC Alias symbAD037
MGC44914
HGNC Previous nameRas association (RalGDS/AF-6) domain family member 4
LocusID (NCBI) 83937
Atlas_Id 42058
Location 10q11.21  [Link to chromosome band 10q11]
Location_base_pair Starts at 44959802 and ends at 44995890 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
APBB3 (5q31.3) / RASSF4 (10q11.21)FCGRT (19q13.33) / RASSF4 (10q11.21)NMRAL1 (16p13.3) / RASSF4 (10q11.21)
RASSF4 (10q11.21) / BPGM (7q33)RASSF4 (10q11.21) / DDB1 (11q12.2)RASSF4 (10q11.21) / DES (2q35)
RASSF4 (10q11.21) / RASSF4 (10q11.21)RASSF4 (10q11.21) / RFC3 (13q13.2)RASSF4 (10q11.21) / TMEM72 (10q11.21)
RASSF4 (10q11.21) / ZNF22 (10q11.21)RASSF4 10q11.21 / TMEM72 10q11.21

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

 

Nomenclature
HGNC (Hugo)RASSF4   20793
Cards
Entrez_Gene (NCBI)RASSF4    Ras association domain family member 4
AliasesAD037
GeneCards (Weizmann)RASSF4
Ensembl hg19 (Hinxton)ENSG00000107551 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000107551 [Gene_View]  ENSG00000107551 [Sequence]  chr10:44959802-44995890 [Contig_View]  RASSF4 [Vega]
ICGC DataPortalENSG00000107551
TCGA cBioPortalRASSF4
AceView (NCBI)RASSF4
Genatlas (Paris)RASSF4
SOURCE (Princeton)RASSF4
Genetics Home Reference (NIH)RASSF4
Genomic and cartography
GoldenPath hg38 (UCSC)RASSF4  -     chr10:44959802-44995890 +  10q11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RASSF4  -     10q11.21   [Description]    (hg19-Feb_2009)
GoldenPathRASSF4 - 10q11.21 [CytoView hg19]  RASSF4 - 10q11.21 [CytoView hg38]
ImmunoBaseENSG00000107551
Genome Data Viewer NCBIRASSF4 [Mapview hg19]  
OMIM610559   
Gene and transcription
Genbank (Entrez)AB209446 AF260335 AK055763 AK092770 AK097272
RefSeq transcript (Entrez)NM_032023 NM_178145
Consensus coding sequences : CCDS (NCBI)RASSF4
Gene ExpressionRASSF4 [ NCBI-GEO ]   RASSF4 [ EBI - ARRAY_EXPRESS ]   RASSF4 [ SEEK ]   RASSF4 [ MEM ]
Gene Expression Viewer (FireBrowse)RASSF4 [ Firebrowse - Broad ]
GenevisibleExpression of RASSF4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)83937
GTEX Portal (Tissue expression)RASSF4
Human Protein AtlasENSG00000107551-RASSF4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H2L5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H2L5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H2L5
PhosPhoSitePlusQ9H2L5
Domaine pattern : Prosite (Expaxy)RA (PS50200)    SARAH (PS50951)   
Domains : Interpro (EBI)C-RASSF    RA_dom    RASSF4    SARAH_dom    Ubiquitin-like_domsf   
Domain families : Pfam (Sanger)Nore1-SARAH (PF16517)    RA (PF00788)   
Domain families : Pfam (NCBI)pfam16517    pfam00788   
Domain families : Smart (EMBL)RA (SM00314)  
Conserved Domain (NCBI)RASSF4
SuperfamilyQ9H2L5
AlphaFold pdb e-kbQ9H2L5   
Human Protein Atlas [tissue]ENSG00000107551-RASSF4 [tissue]
HPRD15219
Protein Interaction databases
DIP (DOE-UCLA)Q9H2L5
IntAct (EBI)Q9H2L5
BioGRIDRASSF4
STRING (EMBL)RASSF4
ZODIACRASSF4
Ontologies - Pathways
QuickGOQ9H2L5
Ontology : AmiGOprotein binding  cell cycle  signal transduction  
Ontology : EGO-EBIprotein binding  cell cycle  signal transduction  
NDEx NetworkRASSF4
Atlas of Cancer Signalling NetworkRASSF4
Wikipedia pathwaysRASSF4
Orthology - Evolution
OrthoDB83937
GeneTree (enSembl)ENSG00000107551
Phylogenetic Trees/Animal Genes : TreeFamRASSF4
Homologs : HomoloGeneRASSF4
Homology/Alignments : Family Browser (UCSC)RASSF4
Gene fusions - Rearrangements
Fusion : MitelmanRASSF4/TMEM72 [10q11.21/10q11.21]  
Fusion : QuiverRASSF4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRASSF4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RASSF4
dbVarRASSF4
ClinVarRASSF4
MonarchRASSF4
1000_GenomesRASSF4 
Exome Variant ServerRASSF4
GNOMAD BrowserENSG00000107551
Varsome BrowserRASSF4
ACMGRASSF4 variants
VarityQ9H2L5
Genomic Variants (DGV)RASSF4 [DGVbeta]
DECIPHERRASSF4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRASSF4 
Mutations
ICGC Data PortalRASSF4 
TCGA Data PortalRASSF4 
Broad Tumor PortalRASSF4
OASIS PortalRASSF4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRASSF4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRASSF4
Mutations and Diseases : HGMDRASSF4
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaRASSF4
DgiDB (Drug Gene Interaction Database)RASSF4
DoCM (Curated mutations)RASSF4
CIViC (Clinical Interpretations of Variants in Cancer)RASSF4
Cancer3DRASSF4
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610559   
Orphanet
DisGeNETRASSF4
MedgenRASSF4
Genetic Testing Registry RASSF4
NextProtQ9H2L5 [Medical]
GENETestsRASSF4
Target ValidationRASSF4
Huge Navigator RASSF4 [HugePedia]
ClinGenRASSF4
Clinical trials, drugs, therapy
MyCancerGenomeRASSF4
Protein Interactions : CTDRASSF4
Pharm GKB GenePA134951366
PharosQ9H2L5
Clinical trialRASSF4
Miscellaneous
canSAR (ICR)RASSF4
HarmonizomeRASSF4
DataMed IndexRASSF4
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRASSF4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:28:22 CEST 2021
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