RASSF8 (Ras association domain family member 8)

2007-02-01  

Identity

HGNC
LOCATION
12p12.1
LOCUSID
ALIAS
C12orf2,HOJ1
FUSION GENES

Other Information

Locus ID:

NCBI: 11228
MIM: 608231
HGNC: 13232
Ensembl: ENSG00000123094

Variants:

dbSNP: 11228
ClinVar: 11228
TCGA: ENSG00000123094
COSMIC: RASSF8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000123094ENST00000282884Q8NHQ8
ENSG00000123094ENST00000282884A0A024RB12
ENSG00000123094ENST00000381352Q8NHQ8
ENSG00000123094ENST00000405154Q8NHQ8
ENSG00000123094ENST00000405154A0A024RB12
ENSG00000123094ENST00000535907F5H8B9
ENSG00000123094ENST00000537946F5H343
ENSG00000123094ENST00000539545H0YG85
ENSG00000123094ENST00000541218F5H0S5
ENSG00000123094ENST00000541490Q8NHQ8
ENSG00000123094ENST00000541490A0A024RB12
ENSG00000123094ENST00000542004F5H7J1
ENSG00000123094ENST00000542315F5GYP8
ENSG00000123094ENST00000542865Q8NHQ8
ENSG00000123094ENST00000542865A0A024RB12
ENSG00000123094ENST00000545413F5H8C5
ENSG00000123094ENST00000611440Q6IB99
ENSG00000123094ENST00000615708Q8NHQ8

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
205140262010The RASSF8 candidate tumor suppressor inhibits cell growth and regulates the Wnt and NF-kappaB signaling pathways.29
281738032017Hypoxia-inducible microRNA-224 promotes the cell growth, migration and invasion by directly targeting RASSF8 in gastric cancer.27
164627602006Identification of RASSF8 as a candidate lung tumor suppressor gene.17
264396872015RASSF8 downregulation promotes lymphangiogenesis and metastasis in esophageal squamous cell carcinoma.10
287709612017The miR-224 promotes non-small cell lung cancer cell proliferation by directly targeting RASSF8.10
263345032015RASSF8 regulates progression of cutaneous melanoma through nuclear factor-κb.6
276269302016Over-Expressed miR-224 Promotes the Progression of Cervical Cancer via Targeting RASSF8.6
171944982007Common polymorphisms in D12S1034 flanking genes RASSF8 and BHLHB3 are not associated with lung adenocarcinoma risk.5
297260112018MiR-505 mediates methotrexate resistance in colorectal cancer by targeting RASSF8.2

Citation

Dessen P

RASSF8 (Ras association domain family member 8)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43852/rassf8