Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

RBBP5 (RB binding protein 5, histone lysine methyltransferase complex subunit)

Identity

Alias_namesSet1c WD40 repeat protein
homolog (S. cerevisiae)
Alias_symbol (synonym)RBQ3
SWD1
Other alias
HGNC (Hugo) RBBP5
LocusID (NCBI) 5929
Atlas_Id 42063
Location 1q32.1  [Link to chromosome band 1q32]
Location_base_pair Starts at 205086142 and ends at 205122022 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
RBBP5 (1q32.1) / GSPT1 (16p13.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RBBP5   9888
Cards
Entrez_Gene (NCBI)RBBP5  5929  RB binding protein 5, histone lysine methyltransferase complex subunit
AliasesRBQ3; SWD1
GeneCards (Weizmann)RBBP5
Ensembl hg19 (Hinxton)ENSG00000117222 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000117222 [Gene_View]  chr1:205086142-205122022 [Contig_View]  RBBP5 [Vega]
ICGC DataPortalENSG00000117222
TCGA cBioPortalRBBP5
AceView (NCBI)RBBP5
Genatlas (Paris)RBBP5
WikiGenes5929
SOURCE (Princeton)RBBP5
Genetics Home Reference (NIH)RBBP5
Genomic and cartography
GoldenPath hg38 (UCSC)RBBP5  -     chr1:205086142-205122022 -  1q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RBBP5  -     1q32.1   [Description]    (hg19-Feb_2009)
EnsemblRBBP5 - 1q32.1 [CytoView hg19]  RBBP5 - 1q32.1 [CytoView hg38]
Mapping of homologs : NCBIRBBP5 [Mapview hg19]  RBBP5 [Mapview hg38]
OMIM600697   
Gene and transcription
Genbank (Entrez)AA235403 AK290137 AK296978 AK297540 AU099032
RefSeq transcript (Entrez)NM_001193272 NM_001193273 NM_005057
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RBBP5
Cluster EST : UnigeneHs.519230 [ NCBI ]
CGAP (NCI)Hs.519230
Alternative Splicing GalleryENSG00000117222
Gene ExpressionRBBP5 [ NCBI-GEO ]   RBBP5 [ EBI - ARRAY_EXPRESS ]   RBBP5 [ SEEK ]   RBBP5 [ MEM ]
Gene Expression Viewer (FireBrowse)RBBP5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5929
GTEX Portal (Tissue expression)RBBP5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15291   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15291  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15291
Splice isoforms : SwissVarQ15291
PhosPhoSitePlusQ15291
Domaine pattern : Prosite (Expaxy)WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_dom   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)RBBP5
DMDM Disease mutations5929
Blocks (Seattle)RBBP5
PDB (SRS)3P4F    4X8N    4X8P    5F6K    5F6L   
PDB (PDBSum)3P4F    4X8N    4X8P    5F6K    5F6L   
PDB (IMB)3P4F    4X8N    4X8P    5F6K    5F6L   
PDB (RSDB)3P4F    4X8N    4X8P    5F6K    5F6L   
Structural Biology KnowledgeBase3P4F    4X8N    4X8P    5F6K    5F6L   
SCOP (Structural Classification of Proteins)3P4F    4X8N    4X8P    5F6K    5F6L   
CATH (Classification of proteins structures)3P4F    4X8N    4X8P    5F6K    5F6L   
SuperfamilyQ15291
Human Protein AtlasENSG00000117222
Peptide AtlasQ15291
HPRD02826
IPIIPI00645975   IPI00478230   IPI00978359   
Protein Interaction databases
DIP (DOE-UCLA)Q15291
IntAct (EBI)Q15291
FunCoupENSG00000117222
BioGRIDRBBP5
STRING (EMBL)RBBP5
ZODIACRBBP5
Ontologies - Pathways
QuickGOQ15291
Ontology : AmiGOprotein binding  nucleus  nucleoplasm  nucleolus  transcription, DNA-templated  regulation of transcription, DNA-templated  cellular response to DNA damage stimulus  histone-lysine N-methyltransferase activity  methylated histone binding  histone methyltransferase complex  histone methyltransferase complex  histone methyltransferase activity (H3-K4 specific)  response to estrogen  transcription regulatory region DNA binding  MLL3/4 complex  Set1C/COMPASS complex  histone H3-K4 methylation  MLL1 complex  beta-catenin-TCF complex assembly  
Ontology : EGO-EBIprotein binding  nucleus  nucleoplasm  nucleolus  transcription, DNA-templated  regulation of transcription, DNA-templated  cellular response to DNA damage stimulus  histone-lysine N-methyltransferase activity  methylated histone binding  histone methyltransferase complex  histone methyltransferase complex  histone methyltransferase activity (H3-K4 specific)  response to estrogen  transcription regulatory region DNA binding  MLL3/4 complex  Set1C/COMPASS complex  histone H3-K4 methylation  MLL1 complex  beta-catenin-TCF complex assembly  
NDEx NetworkRBBP5
Atlas of Cancer Signalling NetworkRBBP5
Wikipedia pathwaysRBBP5
Orthology - Evolution
OrthoDB5929
GeneTree (enSembl)ENSG00000117222
Phylogenetic Trees/Animal Genes : TreeFamRBBP5
HOVERGENQ15291
HOGENOMQ15291
Homologs : HomoloGeneRBBP5
Homology/Alignments : Family Browser (UCSC)RBBP5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRBBP5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RBBP5
dbVarRBBP5
ClinVarRBBP5
1000_GenomesRBBP5 
Exome Variant ServerRBBP5
ExAC (Exome Aggregation Consortium)RBBP5 (select the gene name)
Genetic variants : HAPMAP5929
Genomic Variants (DGV)RBBP5 [DGVbeta]
DECIPHERRBBP5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRBBP5 
Mutations
ICGC Data PortalRBBP5 
TCGA Data PortalRBBP5 
Broad Tumor PortalRBBP5
OASIS PortalRBBP5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRBBP5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRBBP5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RBBP5
DgiDB (Drug Gene Interaction Database)RBBP5
DoCM (Curated mutations)RBBP5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RBBP5 (select a term)
intoGenRBBP5
Cancer3DRBBP5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600697   
Orphanet
MedgenRBBP5
Genetic Testing Registry RBBP5
NextProtQ15291 [Medical]
TSGene5929
GENETestsRBBP5
Target ValidationRBBP5
Huge Navigator RBBP5 [HugePedia]
snp3D : Map Gene to Disease5929
BioCentury BCIQRBBP5
ClinGenRBBP5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5929
Chemical/Pharm GKB GenePA34252
Clinical trialRBBP5
Miscellaneous
canSAR (ICR)RBBP5 (select the gene name)
Probes
Litterature
PubMed89 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRBBP5
EVEXRBBP5
GoPubMedRBBP5
iHOPRBBP5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:28:14 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.