Atlas of Genetics and Cytogenetics in Oncology and Haematology


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RBKS (ribokinase)

Identity

Alias_symbol (synonym)DKFZp686G13268
RBSK
Other aliasRK
HGNC (Hugo) RBKS
LocusID (NCBI) 64080
Atlas_Id 54575
Location 2p23.2  [Link to chromosome band 2p23]
Location_base_pair Starts at 27781364 and ends at 27890396 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CA13 (8q21.2) / RBKS (2p23.2)DTNB (2p23.3) / RBKS (2p23.2)HADHB (2p23.3) / RBKS (2p23.2)
KIF3C (2p23.3) / RBKS (2p23.2)MRPL33 (2p23.2) / RBKS (2p23.2)PPL (16p13.3) / RBKS (2p23.2)
SUPT7L (2p23.3) / RBKS (2p23.2)CA13 8q21.2 / RBKS 2p23.2DTNB 2p23.3 / RBKS 2p23.2
KIF3C 2p23.3 / RBKS 2p23.2MRPL33 2p23.2 / RBKS 2p23.2SUPT7L 2p23.3 / RBKS 2p23.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 7 ]
  t(1;2)(q25;p23) RABGAP1L/RBKS
DTNB/RBKS (2p23)
KIF3C/RBKS (2p23)
MRPL33/RBKS (2p23)
SUPT7L/RBKS (2p23)
t(2;8)(p23;q21) CA13/RBKS
t(2;16)(p23;p13) PPL/RBKS


External links

Nomenclature
HGNC (Hugo)RBKS   30325
Cards
Entrez_Gene (NCBI)RBKS  64080  ribokinase
AliasesRBSK; RK
GeneCards (Weizmann)RBKS
Ensembl hg19 (Hinxton)ENSG00000171174 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171174 [Gene_View]  ENSG00000171174 [Sequence]  chr2:27781364-27890396 [Contig_View]  RBKS [Vega]
ICGC DataPortalENSG00000171174
TCGA cBioPortalRBKS
AceView (NCBI)RBKS
Genatlas (Paris)RBKS
WikiGenes64080
SOURCE (Princeton)RBKS
Genetics Home Reference (NIH)RBKS
Genomic and cartography
GoldenPath hg38 (UCSC)RBKS  -     chr2:27781364-27890396 -  2p23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RBKS  -     2p23.2   [Description]    (hg19-Feb_2009)
EnsemblRBKS - 2p23.2 [CytoView hg19]  RBKS - 2p23.2 [CytoView hg38]
Mapping of homologs : NCBIRBKS [Mapview hg19]  RBKS [Mapview hg38]
OMIM611132   
Gene and transcription
Genbank (Entrez)AJ404857 AK300989 AY643715 BC017425 BF436282
RefSeq transcript (Entrez)NM_001287580 NM_022128
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RBKS
Cluster EST : UnigeneHs.11916 [ NCBI ]
CGAP (NCI)Hs.11916
Alternative Splicing GalleryENSG00000171174
Gene ExpressionRBKS [ NCBI-GEO ]   RBKS [ EBI - ARRAY_EXPRESS ]   RBKS [ SEEK ]   RBKS [ MEM ]
Gene Expression Viewer (FireBrowse)RBKS [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64080
GTEX Portal (Tissue expression)RBKS
Human Protein AtlasENSG00000171174-RBKS [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H477   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H477  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H477
Splice isoforms : SwissVarQ9H477
PhosPhoSitePlusQ9H477
Domaine pattern : Prosite (Expaxy)PFKB_KINASES_2 (PS00584)   
Domains : Interpro (EBI)Carboh/pur_kinase_PfkB_CS    D_ribokin    PfkB_dom    Ribo/fructo_kinase    Ribokinase-like   
Domain families : Pfam (Sanger)PfkB (PF00294)   
Domain families : Pfam (NCBI)pfam00294   
Conserved Domain (NCBI)RBKS
DMDM Disease mutations64080
Blocks (Seattle)RBKS
PDB (SRS)2FV7    5BYC    5BYD    5BYE    5BYF    5C3Y    5C3Z    5C40    5C41   
PDB (PDBSum)2FV7    5BYC    5BYD    5BYE    5BYF    5C3Y    5C3Z    5C40    5C41   
PDB (IMB)2FV7    5BYC    5BYD    5BYE    5BYF    5C3Y    5C3Z    5C40    5C41   
PDB (RSDB)2FV7    5BYC    5BYD    5BYE    5BYF    5C3Y    5C3Z    5C40    5C41   
Structural Biology KnowledgeBase2FV7    5BYC    5BYD    5BYE    5BYF    5C3Y    5C3Z    5C40    5C41   
SCOP (Structural Classification of Proteins)2FV7    5BYC    5BYD    5BYE    5BYF    5C3Y    5C3Z    5C40    5C41   
CATH (Classification of proteins structures)2FV7    5BYC    5BYD    5BYE    5BYF    5C3Y    5C3Z    5C40    5C41   
SuperfamilyQ9H477
Human Protein Atlas [tissue]ENSG00000171174-RBKS [tissue]
Peptide AtlasQ9H477
HPRD15222
IPIIPI00005487   IPI00894412   IPI00893648   IPI00894063   
Protein Interaction databases
DIP (DOE-UCLA)Q9H477
IntAct (EBI)Q9H477
FunCoupENSG00000171174
BioGRIDRBKS
STRING (EMBL)RBKS
ZODIACRBKS
Ontologies - Pathways
QuickGOQ9H477
Ontology : AmiGOribokinase activity  protein binding  ATP binding  nucleus  cytoplasm  cytosol  pentose-phosphate shunt  carbohydrate kinase activity  D-ribose catabolic process  carbohydrate phosphorylation  metal ion binding  
Ontology : EGO-EBIribokinase activity  protein binding  ATP binding  nucleus  cytoplasm  cytosol  pentose-phosphate shunt  carbohydrate kinase activity  D-ribose catabolic process  carbohydrate phosphorylation  metal ion binding  
Pathways : KEGGPentose phosphate pathway   
NDEx NetworkRBKS
Atlas of Cancer Signalling NetworkRBKS
Wikipedia pathwaysRBKS
Orthology - Evolution
OrthoDB64080
GeneTree (enSembl)ENSG00000171174
Phylogenetic Trees/Animal Genes : TreeFamRBKS
HOVERGENQ9H477
HOGENOMQ9H477
Homologs : HomoloGeneRBKS
Homology/Alignments : Family Browser (UCSC)RBKS
Gene fusions - Rearrangements
Fusion : MitelmanCA13/RBKS [8q21.2/2p23.2]  [t(2;8)(p23;q21)]  
Fusion : MitelmanDTNB/RBKS [2p23.3/2p23.2]  [t(2;2)(p23;p23)]  
Fusion : MitelmanKIF3C/RBKS [2p23.3/2p23.2]  [t(2;2)(p23;p23)]  
Fusion : MitelmanMRPL33/RBKS [2p23.2/2p23.2]  [t(2;2)(p23;p23)]  
Fusion : MitelmanPPL/RBKS [16p13.3/2p23.2]  [t(2;16)(p23;p13)]  
Fusion : MitelmanSUPT7L/RBKS [2p23.3/2p23.2]  [t(2;2)(p23;p23)]  
Fusion PortalCA13 8q21.2 RBKS 2p23.2 BRCA
Fusion PortalDTNB 2p23.3 RBKS 2p23.2 BRCA
Fusion PortalKIF3C 2p23.3 RBKS 2p23.2 OV
Fusion PortalMRPL33 2p23.2 RBKS 2p23.2 LUAD
Fusion PortalSUPT7L 2p23.3 RBKS 2p23.2 HNSC
Fusion Cancer (Beijing)HADHB [2p23.3]  -  RBKS [2p23.2]  [FUSC000172]  [FUSC000172]  [FUSC000172]
Fusion : QuiverRBKS
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRBKS [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RBKS
dbVarRBKS
ClinVarRBKS
1000_GenomesRBKS 
Exome Variant ServerRBKS
ExAC (Exome Aggregation Consortium)ENSG00000171174
GNOMAD BrowserENSG00000171174
Varsome BrowserRBKS
Genetic variants : HAPMAP64080
Genomic Variants (DGV)RBKS [DGVbeta]
DECIPHERRBKS [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRBKS 
Mutations
ICGC Data PortalRBKS 
TCGA Data PortalRBKS 
Broad Tumor PortalRBKS
OASIS PortalRBKS [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRBKS  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRBKS
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RBKS
DgiDB (Drug Gene Interaction Database)RBKS
DoCM (Curated mutations)RBKS (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RBKS (select a term)
intoGenRBKS
Cancer3DRBKS(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611132   
Orphanet
DisGeNETRBKS
MedgenRBKS
Genetic Testing Registry RBKS
NextProtQ9H477 [Medical]
TSGene64080
GENETestsRBKS
Target ValidationRBKS
Huge Navigator RBKS [HugePedia]
snp3D : Map Gene to Disease64080
BioCentury BCIQRBKS
ClinGenRBKS
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64080
Chemical/Pharm GKB GenePA134951602
Clinical trialRBKS
Miscellaneous
canSAR (ICR)RBKS (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRBKS
EVEXRBKS
GoPubMedRBKS
iHOPRBKS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Aug 27 11:48:29 CEST 2018

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