RBM14 (RNA binding motif protein 14)

2004-04-01  

Identity

HGNC
RBM14
LOCATION
11q13.2
LOCUSID
10432
ALIAS
COAA,PSP2,SIP,SYTIP1,TMEM137
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10432
MIM: 612409
HGNC: 14219
Ensembl: ENSG00000239306

Variants:

dbSNP: 10432
ClinVar: 10432
TCGA: ENSG00000239306
COSMIC: RBM14

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000239306ENST00000310137Q96PK6
ENSG00000239306ENST00000310137A0A0S2Z4Z0
ENSG00000239306ENST00000393979Q96PK6
ENSG00000239306ENST00000393979A0A0S2Z567
ENSG00000239306ENST00000409372B8ZZ74
ENSG00000239306ENST00000409738Q96PK6
ENSG00000239306ENST00000409738A0A0S2Z5V2
ENSG00000239306ENST00000443702F8WDX3

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
262837962015Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles.76
146731762004CoAA, a nuclear receptor coactivator protein at the interface of transcriptional coactivation and RNA splicing.65
114431122001Identification and characterization of RRM-containing coactivator activator (CoAA) as TRBP-interacting protein, and its splice variant as a coactivator modulator (CoAM).52
162276272005The proto-oncoprotein SYT interacts with SYT-interacting protein/co-activator activator (SIP/CoAA), a human nuclear receptor co-activator with similarity to EWS and TLS/FUS family of proteins.16
255896582015Mining the human complexome database identifies RBM14 as an XPO1-associated protein involved in HIV-1 Rev function.15
194169632009Functional pre- mRNA trans-splicing of coactivator CoAA and corepressor RBM4 during stem/progenitor cell differentiation.14
248112422014RNA binding protein RBM14 promotes radio-resistance in glioblastoma by regulating DNA repair and cell differentiation.14
253858352015RBM14 prevents assembly of centriolar protein complexes and maintains mitotic spindle integrity.14
168781472007Gene amplification and associated loss of 5' regulatory sequences of CoAA in human cancers.12
173374382007Switched alternative splicing of oncogene CoAA during embryonal carcinoma stem cell differentiation.12

Citation

Dessen P

RBM14 (RNA binding motif protein 14)

Atlas Genet Cytogenet Oncol Haematol. 2004-04-01

Online version: http://atlasgeneticsoncology.org/gene/42068/rbm14