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RBM3 (RNA binding motif protein 3)

Identity

Alias (NCBI)IS1-RNPL
RNPL
HGNC (Hugo) RBM3
HGNC Alias symbIS1-RNPL
LocusID (NCBI) 5935
Atlas_Id 43710
Location Xp11.23  [Link to chromosome band Xp11]
Location_base_pair Starts at 48574484 and ends at 48581161 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NEGR1 (1p31.1)::RBM3 (Xp11.23)RBM3 (Xp11.23)::F3 (1p21.3)RBM3 (Xp11.23)::IGF1 (12q23.2)
RBM3 (Xp11.23)::ILK (11p15.4)RBM3 (Xp11.23)::NME7 (1q24.2)RBM3 (Xp11.23)::RBM3 (Xp11.23)
RBM3 (Xp11.23)::SIKE1 (1p13.2)SECISBP2 (9q22.2)::RBM3 (Xp11.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(X;6)(p11;q21) CD24::RBM3


External links

 

Nomenclature
HGNC (Hugo)RBM3   9900
Cards
Entrez_Gene (NCBI)RBM3    RNA binding motif protein 3
AliasesIS1-RNPL; RNPL
GeneCards (Weizmann)RBM3
Ensembl hg19 (Hinxton)ENSG00000102317 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000102317 [Gene_View]  ENSG00000102317 [Sequence]  chrX:48574484-48581161 [Contig_View]  RBM3 [Vega]
ICGC DataPortalENSG00000102317
TCGA cBioPortalRBM3
AceView (NCBI)RBM3
Genatlas (Paris)RBM3
SOURCE (Princeton)RBM3
Genetics Home Reference (NIH)RBM3
Genomic and cartography
GoldenPath hg38 (UCSC)RBM3  -     chrX:48574484-48581161 +  Xp11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RBM3  -     Xp11.23   [Description]    (hg19-Feb_2009)
GoldenPathRBM3 - Xp11.23 [CytoView hg19]  RBM3 - Xp11.23 [CytoView hg38]
ImmunoBaseENSG00000102317
Genome Data Viewer NCBIRBM3 [Mapview hg19]  
OMIM300027   
Gene and transcription
Genbank (Entrez)AA460548 AK000859 AK026664 AK289614 AK309137
RefSeq transcript (Entrez)NM_001017430 NM_001017431 NM_006743
Consensus coding sequences : CCDS (NCBI)RBM3
Gene ExpressionRBM3 [ NCBI-GEO ]   RBM3 [ EBI - ARRAY_EXPRESS ]   RBM3 [ SEEK ]   RBM3 [ MEM ]
Gene Expression Viewer (FireBrowse)RBM3 [ Firebrowse - Broad ]
GenevisibleExpression of RBM3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5935
GTEX Portal (Tissue expression)RBM3
Human Protein AtlasENSG00000102317-RBM3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP98179   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP98179  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP98179
PhosPhoSitePlusP98179
Domaine pattern : Prosite (Expaxy)RRM (PS50102)   
Domains : Interpro (EBI)Nucleotide-bd_a/b_plait_sf    RBD_domain_sf    RBM3/CIRBP_RRM    RRM_dom   
Domain families : Pfam (Sanger)RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam00076   
Domain families : Smart (EMBL)RRM (SM00360)  
Conserved Domain (NCBI)RBM3
SuperfamilyP98179
AlphaFold pdb e-kbP98179   
Human Protein Atlas [tissue]ENSG00000102317-RBM3 [tissue]
HPRD02067
Protein Interaction databases
DIP (DOE-UCLA)P98179
IntAct (EBI)P98179
BioGRIDRBM3
STRING (EMBL)RBM3
ZODIACRBM3
Ontologies - Pathways
QuickGOP98179
Ontology : AmiGORNA binding  protein binding  nucleus  nucleoplasm  spliceosomal complex  cytoplasm  RNA processing  regulation of translation  regulation of translation  dendrite  ribosomal large subunit binding  positive regulation of translation  positive regulation of mRNA splicing, via spliceosome  
Ontology : EGO-EBIRNA binding  protein binding  nucleus  nucleoplasm  spliceosomal complex  cytoplasm  RNA processing  regulation of translation  regulation of translation  dendrite  ribosomal large subunit binding  positive regulation of translation  positive regulation of mRNA splicing, via spliceosome  
NDEx NetworkRBM3
Atlas of Cancer Signalling NetworkRBM3
Wikipedia pathwaysRBM3
Orthology - Evolution
OrthoDB5935
GeneTree (enSembl)ENSG00000102317
Phylogenetic Trees/Animal Genes : TreeFamRBM3
Homologs : HomoloGeneRBM3
Homology/Alignments : Family Browser (UCSC)RBM3
Gene fusions - Rearrangements
Fusion : QuiverRBM3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRBM3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RBM3
dbVarRBM3
ClinVarRBM3
MonarchRBM3
1000_GenomesRBM3 
Exome Variant ServerRBM3
GNOMAD BrowserENSG00000102317
Varsome BrowserRBM3
ACMGRBM3 variants
VarityP98179
Genomic Variants (DGV)RBM3 [DGVbeta]
DECIPHERRBM3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRBM3 
Mutations
ICGC Data PortalRBM3 
TCGA Data PortalRBM3 
Broad Tumor PortalRBM3
OASIS PortalRBM3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRBM3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRBM3
Mutations and Diseases : HGMDRBM3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaRBM3
DgiDB (Drug Gene Interaction Database)RBM3
DoCM (Curated mutations)RBM3
CIViC (Clinical Interpretations of Variants in Cancer)RBM3
Cancer3DRBM3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300027   
Orphanet
DisGeNETRBM3
MedgenRBM3
Genetic Testing Registry RBM3
NextProtP98179 [Medical]
GENETestsRBM3
Target ValidationRBM3
Huge Navigator RBM3 [HugePedia]
ClinGenRBM3
Clinical trials, drugs, therapy
MyCancerGenomeRBM3
Protein Interactions : CTDRBM3
Pharm GKB GenePA34265
PharosP98179
Clinical trialRBM3
Miscellaneous
canSAR (ICR)RBM3
HarmonizomeRBM3
ARCHS4RBM3
DataMed IndexRBM3
Probes
Litterature
PubMed90 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRBM3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Sun Jan 16 18:30:43 CET 2022

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