RBMS3 (RNA binding motif single stranded interacting protein 3)

2012-01-01  

Identity

HGNC
LOCATION
3p24.1
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 27303
MIM: 605786
HGNC: 13427
Ensembl: ENSG00000144642

Variants:

dbSNP: 27303
ClinVar: 27303
TCGA: ENSG00000144642
COSMIC: RBMS3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144642ENST00000273139Q6XE24
ENSG00000144642ENST00000383766Q6XE24
ENSG00000144642ENST00000383767Q6XE24
ENSG00000144642ENST00000434693C9JIJ9
ENSG00000144642ENST00000445033C9J9B2
ENSG00000144642ENST00000452462Q6XE24
ENSG00000144642ENST00000456853Q6XE24
ENSG00000144642ENST00000636680A0A1B0GUW5
ENSG00000144642ENST00000637842A0A1B0GTI7

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA164712563BisphosphonatesChemicalClinicalAnnotationassociatedPD
PA445187OsteonecrosisDiseaseClinicalAnnotationassociatedPD

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
175865242007RNA-binding protein RBMS3 is expressed in activated hepatic stellate cells and liver fibrosis and increases expression of transcription factor Prx1.18
218441832011Downregulation of RBMS3 is associated with poor prognosis in esophageal squamous cell carcinoma.17
222678512012Genomewide pharmacogenetics of bisphosphonate-induced osteonecrosis of the jaw: the role of RBMS3.11
229570922012RBMS3 at 3p24 inhibits nasopharyngeal carcinoma development via inhibiting cell proliferation, angiogenesis, and inducing apoptosis.11
230451562013Gene-gene interaction between RBMS3 and ZNF516 influences bone mineral density.11
255889242015RBMS3 is a tumor suppressor gene that acts as a favorable prognostic marker in lung squamous cell carcinoma.9
302792312019Loss of RBMS3 Confers Platinum Resistance in Epithelial Ovarian Cancer via Activation of miR-126-5p/β-catenin/CBP signaling.8
275032882016Identification of susceptibility gene associated with female primary Sjögren's syndrome in Han Chinese by genome-wide association study.6
279024802017Down regulation of RNA binding motif, single-stranded interacting protein 3, along with up regulation of nuclear HIF1A correlates with poor prognosis in patients with gastric cancer.5

Citation

Dessen P

RBMS3 (RNA binding motif single stranded interacting protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2012-01-01

Online version: http://atlasgeneticsoncology.org/gene/52537/rbms3