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RBP4 (retinol binding protein 4)

Identity

Alias_namesretinol-binding protein 4
Other aliasMCOPCB10
RDCCAS
HGNC (Hugo) RBP4
LocusID (NCBI) 5950
Atlas_Id 50989
Location 10q23.33  [Link to chromosome band 10q23]
Location_base_pair Starts at 93591836 and ends at 93601513 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
HBG1 (11p15.4) / RBP4 (10q23.33)MYOF (10q23.33) / RBP4 (10q23.33)RBP4 (10q23.33) / ZDHHC17 (12q21.2)
SUCLG2 (3p14.1) / RBP4 (10q23.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RBP4   9922
Cards
Entrez_Gene (NCBI)RBP4  5950  retinol binding protein 4
AliasesMCOPCB10; RDCCAS
GeneCards (Weizmann)RBP4
Ensembl hg19 (Hinxton)ENSG00000138207 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138207 [Gene_View]  chr10:93591836-93601513 [Contig_View]  RBP4 [Vega]
ICGC DataPortalENSG00000138207
TCGA cBioPortalRBP4
AceView (NCBI)RBP4
Genatlas (Paris)RBP4
WikiGenes5950
SOURCE (Princeton)RBP4
Genetics Home Reference (NIH)RBP4
Genomic and cartography
GoldenPath hg38 (UCSC)RBP4  -     chr10:93591836-93601513 -  10q23.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RBP4  -     10q23.33   [Description]    (hg19-Feb_2009)
EnsemblRBP4 - 10q23.33 [CytoView hg19]  RBP4 - 10q23.33 [CytoView hg38]
Mapping of homologs : NCBIRBP4 [Mapview hg19]  RBP4 [Mapview hg38]
OMIM180250   615147   616428   
Gene and transcription
Genbank (Entrez)BC020633 BG565176 BI712834 BX495987 DQ891381
RefSeq transcript (Entrez)NM_001323517 NM_001323518 NM_006744
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RBP4
Cluster EST : UnigeneHs.50223 [ NCBI ]
CGAP (NCI)Hs.50223
Alternative Splicing GalleryENSG00000138207
Gene ExpressionRBP4 [ NCBI-GEO ]   RBP4 [ EBI - ARRAY_EXPRESS ]   RBP4 [ SEEK ]   RBP4 [ MEM ]
Gene Expression Viewer (FireBrowse)RBP4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5950
GTEX Portal (Tissue expression)RBP4
Protein : pattern, domain, 3D structure
UniProt/SwissProtP02753   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP02753  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP02753
Splice isoforms : SwissVarP02753
PhosPhoSitePlusP02753
Domaine pattern : Prosite (Expaxy)LIPOCALIN (PS00213)   
Domains : Interpro (EBI)Calycin    Calycin-like    Lipocalin    Lipocalin_ApoD    Lipocalin_CS    Lipocln_cytosolic_FA-bd_dom    Retinol-bd/Purpurin   
Domain families : Pfam (Sanger)Lipocalin (PF00061)   
Domain families : Pfam (NCBI)pfam00061   
Conserved Domain (NCBI)RBP4
DMDM Disease mutations5950
Blocks (Seattle)RBP4
PDB (SRS)1BRP    1BRQ    1JYD    1JYJ    1QAB    1RBP    1RLB    2WQ9    2WQA    2WR6    3BSZ    3FMZ    4O9S    4PSQ   
PDB (PDBSum)1BRP    1BRQ    1JYD    1JYJ    1QAB    1RBP    1RLB    2WQ9    2WQA    2WR6    3BSZ    3FMZ    4O9S    4PSQ   
PDB (IMB)1BRP    1BRQ    1JYD    1JYJ    1QAB    1RBP    1RLB    2WQ9    2WQA    2WR6    3BSZ    3FMZ    4O9S    4PSQ   
PDB (RSDB)1BRP    1BRQ    1JYD    1JYJ    1QAB    1RBP    1RLB    2WQ9    2WQA    2WR6    3BSZ    3FMZ    4O9S    4PSQ   
Structural Biology KnowledgeBase1BRP    1BRQ    1JYD    1JYJ    1QAB    1RBP    1RLB    2WQ9    2WQA    2WR6    3BSZ    3FMZ    4O9S    4PSQ   
SCOP (Structural Classification of Proteins)1BRP    1BRQ    1JYD    1JYJ    1QAB    1RBP    1RLB    2WQ9    2WQA    2WR6    3BSZ    3FMZ    4O9S    4PSQ   
CATH (Classification of proteins structures)1BRP    1BRQ    1JYD    1JYJ    1QAB    1RBP    1RLB    2WQ9    2WQA    2WR6    3BSZ    3FMZ    4O9S    4PSQ   
SuperfamilyP02753
Human Protein AtlasENSG00000138207
Peptide AtlasP02753
HPRD01580
IPIIPI00022420   IPI00844536   IPI00480192   
Protein Interaction databases
DIP (DOE-UCLA)P02753
IntAct (EBI)P02753
FunCoupENSG00000138207
BioGRIDRBP4
STRING (EMBL)RBP4
ZODIACRBP4
Ontologies - Pathways
QuickGOP02753
Ontology : AmiGOretinoid metabolic process  eye development  eye development  protein binding  extracellular region  extracellular space  extracellular space  cytosol  gluconeogenesis  gluconeogenesis  heart development  visual perception  retinal binding  retinol binding  maintenance of gastrointestinal epithelium  lung development  positive regulation of insulin secretion  response to retinoic acid  retinol transporter activity  retinol transport  retinol metabolic process  glucose homeostasis  protein complex  response to ethanol  protein heterodimerization activity  embryonic organ morphogenesis  embryonic skeletal system development  cardiac muscle tissue development  female genitalia morphogenesis  positive regulation of immunoglobulin secretion  negative regulation of cardiac muscle cell proliferation  embryonic retina morphogenesis in camera-type eye  uterus development  vagina development  urinary bladder development  heart trabecula formation  extracellular exosome  
Ontology : EGO-EBIretinoid metabolic process  eye development  eye development  protein binding  extracellular region  extracellular space  extracellular space  cytosol  gluconeogenesis  gluconeogenesis  heart development  visual perception  retinal binding  retinol binding  maintenance of gastrointestinal epithelium  lung development  positive regulation of insulin secretion  response to retinoic acid  retinol transporter activity  retinol transport  retinol metabolic process  glucose homeostasis  protein complex  response to ethanol  protein heterodimerization activity  embryonic organ morphogenesis  embryonic skeletal system development  cardiac muscle tissue development  female genitalia morphogenesis  positive regulation of immunoglobulin secretion  negative regulation of cardiac muscle cell proliferation  embryonic retina morphogenesis in camera-type eye  uterus development  vagina development  urinary bladder development  heart trabecula formation  extracellular exosome  
NDEx NetworkRBP4
Atlas of Cancer Signalling NetworkRBP4
Wikipedia pathwaysRBP4
Orthology - Evolution
OrthoDB5950
GeneTree (enSembl)ENSG00000138207
Phylogenetic Trees/Animal Genes : TreeFamRBP4
HOVERGENP02753
HOGENOMP02753
Homologs : HomoloGeneRBP4
Homology/Alignments : Family Browser (UCSC)RBP4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRBP4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RBP4
dbVarRBP4
ClinVarRBP4
1000_GenomesRBP4 
Exome Variant ServerRBP4
ExAC (Exome Aggregation Consortium)RBP4 (select the gene name)
Genetic variants : HAPMAP5950
Genomic Variants (DGV)RBP4 [DGVbeta]
DECIPHERRBP4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRBP4 
Mutations
ICGC Data PortalRBP4 
TCGA Data PortalRBP4 
Broad Tumor PortalRBP4
OASIS PortalRBP4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRBP4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRBP4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Eye diseases - LOVD
BioMutasearch RBP4
DgiDB (Drug Gene Interaction Database)RBP4
DoCM (Curated mutations)RBP4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RBP4 (select a term)
intoGenRBP4
Cancer3DRBP4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM180250    615147    616428   
Orphanet22106    13955   
MedgenRBP4
Genetic Testing Registry RBP4
NextProtP02753 [Medical]
TSGene5950
GENETestsRBP4
Target ValidationRBP4
Huge Navigator RBP4 [HugePedia]
snp3D : Map Gene to Disease5950
BioCentury BCIQRBP4
ClinGenRBP4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5950
Chemical/Pharm GKB GenePA34289
Clinical trialRBP4
Miscellaneous
canSAR (ICR)RBP4 (select the gene name)
Probes
Litterature
PubMed286 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRBP4
EVEXRBP4
GoPubMedRBP4
iHOPRBP4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:12:44 CEST 2017

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