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RCC1 (regulator of chromosome condensation 1)

Identity

Alias_namesCHC1
chromosome condensation 1
Other aliasRCC1-I
SNHG3-RCC1
HGNC (Hugo) RCC1
LocusID (NCBI) 1104
Atlas_Id 40069
Location 1p35.3  [Link to chromosome band 1p35]
Location_base_pair Starts at 28844745 and ends at 28865708 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DIRC1 (2q32.2) / RCC1 (1p35.3)MYC (8q24.21) / RCC1 (1p35.3)PHACTR4 (1p35.3) / RCC1 (1p35.3)
RCC1 (1p35.3) / DIRC1 (2q32.2)RCC1 (1p35.3) / MYC (8q24.21)RCC1 (1p35.3) / PICALM (11q14.2)
RCC1 (1p35.3) / RCC1 (1p35.3)RCC1 (1p35.3) / SERINC2 (1p35.2)RCC1 (1p35.3) / UBE2D2 (5q31.2)
SNHG3 (1p35.3) / RCC1 (1p35.3)TRNAU1AP (1p35.3) / RCC1 (1p35.3)RCC1 1p35.3 / SERINC2 1p35.2
TRNAU1AP 1p35.3 / RCC1 1p35.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RCC1   1913
Cards
Entrez_Gene (NCBI)RCC1  1104  regulator of chromosome condensation 1
AliasesCHC1; RCC1-I; SNHG3-RCC1
GeneCards (Weizmann)RCC1
Ensembl hg19 (Hinxton)ENSG00000180198 [Gene_View]  chr1:28844745-28865708 [Contig_View]  RCC1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000180198 [Gene_View]  chr1:28844745-28865708 [Contig_View]  RCC1 [Vega]
ICGC DataPortalENSG00000180198
TCGA cBioPortalRCC1
AceView (NCBI)RCC1
Genatlas (Paris)RCC1
WikiGenes1104
SOURCE (Princeton)RCC1
Genetics Home Reference (NIH)RCC1
Genomic and cartography
GoldenPath hg19 (UCSC)RCC1  -     chr1:28844745-28865708 +  1p35.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RCC1  -     1p35.3   [Description]    (hg38-Dec_2013)
EnsemblRCC1 - 1p35.3 [CytoView hg19]  RCC1 - 1p35.3 [CytoView hg38]
Mapping of homologs : NCBIRCC1 [Mapview hg19]  RCC1 [Mapview hg38]
OMIM179710   
Gene and transcription
Genbank (Entrez)AF498924 AI198971 BC001589 BC010067 BC069198
RefSeq transcript (Entrez)NM_001048194 NM_001048195 NM_001048199 NM_001269
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_032977 NW_004929289
Consensus coding sequences : CCDS (NCBI)RCC1
Cluster EST : UnigeneHs.469723 [ NCBI ]
CGAP (NCI)Hs.469723
Alternative Splicing GalleryENSG00000180198
Gene ExpressionRCC1 [ NCBI-GEO ]   RCC1 [ EBI - ARRAY_EXPRESS ]   RCC1 [ SEEK ]   RCC1 [ MEM ]
Gene Expression Viewer (FireBrowse)RCC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1104
GTEX Portal (Tissue expression)RCC1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP18754   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP18754  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP18754
Splice isoforms : SwissVarP18754
PhosPhoSitePlusP18754
Domaine pattern : Prosite (Expaxy)RCC1_1 (PS00625)    RCC1_2 (PS00626)    RCC1_3 (PS50012)   
Domains : Interpro (EBI)RCC1/BLIP-II    Reg_chr_condens   
Domain families : Pfam (Sanger)RCC1 (PF00415)   
Domain families : Pfam (NCBI)pfam00415   
Conserved Domain (NCBI)RCC1
DMDM Disease mutations1104
Blocks (Seattle)RCC1
PDB (SRS)1A12    1I2M    5E1B    5E1D    5E1M    5E1O    5E2A    5E2B   
PDB (PDBSum)1A12    1I2M    5E1B    5E1D    5E1M    5E1O    5E2A    5E2B   
PDB (IMB)1A12    1I2M    5E1B    5E1D    5E1M    5E1O    5E2A    5E2B   
PDB (RSDB)1A12    1I2M    5E1B    5E1D    5E1M    5E1O    5E2A    5E2B   
Structural Biology KnowledgeBase1A12    1I2M    5E1B    5E1D    5E1M    5E1O    5E2A    5E2B   
SCOP (Structural Classification of Proteins)1A12    1I2M    5E1B    5E1D    5E1M    5E1O    5E2A    5E2B   
CATH (Classification of proteins structures)1A12    1I2M    5E1B    5E1D    5E1M    5E1O    5E2A    5E2B   
SuperfamilyP18754
Human Protein AtlasENSG00000180198
Peptide AtlasP18754
HPRD01559
IPIIPI00747309   IPI00001661   IPI00787306   IPI00927389   IPI00925317   IPI00926548   IPI00925791   IPI00925570   
Protein Interaction databases
DIP (DOE-UCLA)P18754
IntAct (EBI)P18754
FunCoupENSG00000180198
BioGRIDRCC1
STRING (EMBL)RCC1
ZODIACRCC1
Ontologies - Pathways
QuickGOP18754
Ontology : AmiGOG1/S transition of mitotic cell cycle  nuclear chromatin  condensed nuclear chromosome  chromatin binding  Ran guanyl-nucleotide exchange factor activity  Ran guanyl-nucleotide exchange factor activity  protein binding  nucleus  nucleoplasm  nucleoplasm  cytoplasm  mitotic spindle organization  chromosome segregation  mitotic nuclear division  regulation of mitotic nuclear division  viral process  nucleosomal DNA binding  nuclear membrane  histone binding  positive regulation of GTPase activity  positive regulation of GTPase activity  positive regulation of GTPase activity  spindle assembly  cell division  
Ontology : EGO-EBIG1/S transition of mitotic cell cycle  nuclear chromatin  condensed nuclear chromosome  chromatin binding  Ran guanyl-nucleotide exchange factor activity  Ran guanyl-nucleotide exchange factor activity  protein binding  nucleus  nucleoplasm  nucleoplasm  cytoplasm  mitotic spindle organization  chromosome segregation  mitotic nuclear division  regulation of mitotic nuclear division  viral process  nucleosomal DNA binding  nuclear membrane  histone binding  positive regulation of GTPase activity  positive regulation of GTPase activity  positive regulation of GTPase activity  spindle assembly  cell division  
Pathways : BIOCARTACycling of Ran in nucleocytoplasmic transport [Genes]    Mechanism of Protein Import into the Nucleus [Genes]    Role of Ran in mitotic spindle regulation [Genes]   
NDEx NetworkRCC1
Atlas of Cancer Signalling NetworkRCC1
Wikipedia pathwaysRCC1
Orthology - Evolution
OrthoDB1104
GeneTree (enSembl)ENSG00000180198
Phylogenetic Trees/Animal Genes : TreeFamRCC1
HOVERGENP18754
HOGENOMP18754
Homologs : HomoloGeneRCC1
Homology/Alignments : Family Browser (UCSC)RCC1
Gene fusions - Rearrangements
Fusion : MitelmanPHACTR4/RCC1 [1p35.3/1p35.3]  [t(1;1)(p35;p35)]  
Fusion : MitelmanRCC1/PICALM [1p35.3/11q14.2]  [t(1;11)(p35;q14)]  
Fusion : MitelmanRCC1/SERINC2 [1p35.3/1p35.2]  [t(1;1)(p35;p35)]  
Fusion : MitelmanRCC1/UBE2D2 [1p35.3/5q31.2]  [t(1;5)(p35;q31)]  
Fusion : MitelmanTRNAU1AP/RCC1 [1p35.3/1p35.3]  [t(1;1)(p35;p35)]  
Fusion: TCGARCC1 1p35.3 SERINC2 1p35.2 HNSC
Fusion: TCGATRNAU1AP 1p35.3 RCC1 1p35.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRCC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RCC1
dbVarRCC1
ClinVarRCC1
1000_GenomesRCC1 
Exome Variant ServerRCC1
ExAC (Exome Aggregation Consortium)RCC1 (select the gene name)
Genetic variants : HAPMAP1104
Genomic Variants (DGV)RCC1 [DGVbeta]
DECIPHER (Syndromes)1:28844745-28865708  ENSG00000180198
CONAN: Copy Number AnalysisRCC1 
Mutations
ICGC Data PortalRCC1 
TCGA Data PortalRCC1 
Broad Tumor PortalRCC1
OASIS PortalRCC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRCC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRCC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RCC1
DgiDB (Drug Gene Interaction Database)RCC1
DoCM (Curated mutations)RCC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RCC1 (select a term)
intoGenRCC1
Cancer3DRCC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM179710   
Orphanet
MedgenRCC1
Genetic Testing Registry RCC1
NextProtP18754 [Medical]
TSGene1104
GENETestsRCC1
Huge Navigator RCC1 [HugePedia]
snp3D : Map Gene to Disease1104
BioCentury BCIQRCC1
ClinGenRCC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1104
Chemical/Pharm GKB GenePA26449
Clinical trialRCC1
Miscellaneous
canSAR (ICR)RCC1 (select the gene name)
Probes
Litterature
PubMed75 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRCC1
EVEXRCC1
GoPubMedRCC1
iHOPRCC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:17:08 CEST 2017

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