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RCC2 (regulator of chromosome condensation 2)

Identity

Alias (NCBI)TD-60
HGNC (Hugo) RCC2
HGNC Alias symbTD-60
LocusID (NCBI) 55920
Atlas_Id 53610
Location 1p36.13  [Link to chromosome band 1p36]
Location_base_pair Starts at 17406760 and ends at 17439677 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CD68 (17p13.1) / RCC2 (1p36.13)MINOS1 (1p36.13) / RCC2 (1p36.13)RCC2 (1p36.13) / PADI4 (1p36.13)
RCC2 1p36.13 / PADI4 1p36.13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)RCC2   30297
Cards
Entrez_Gene (NCBI)RCC2    regulator of chromosome condensation 2
AliasesTD-60
GeneCards (Weizmann)RCC2
Ensembl hg19 (Hinxton)ENSG00000179051 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000179051 [Gene_View]  ENSG00000179051 [Sequence]  chr1:17406760-17439677 [Contig_View]  RCC2 [Vega]
ICGC DataPortalENSG00000179051
TCGA cBioPortalRCC2
AceView (NCBI)RCC2
Genatlas (Paris)RCC2
SOURCE (Princeton)RCC2
Genetics Home Reference (NIH)RCC2
Genomic and cartography
GoldenPath hg38 (UCSC)RCC2  -     chr1:17406760-17439677 -  1p36.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RCC2  -     1p36.13   [Description]    (hg19-Feb_2009)
GoldenPathRCC2 - 1p36.13 [CytoView hg19]  RCC2 - 1p36.13 [CytoView hg38]
ImmunoBaseENSG00000179051
Genome Data Viewer NCBIRCC2 [Mapview hg19]  
OMIM609587   
Gene and transcription
Genbank (Entrez)AB040903 AJ421269 AK026005 AK126021 AL359612
RefSeq transcript (Entrez)NM_001136204 NM_018715
Consensus coding sequences : CCDS (NCBI)RCC2
Gene ExpressionRCC2 [ NCBI-GEO ]   RCC2 [ EBI - ARRAY_EXPRESS ]   RCC2 [ SEEK ]   RCC2 [ MEM ]
Gene Expression Viewer (FireBrowse)RCC2 [ Firebrowse - Broad ]
GenevisibleExpression of RCC2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55920
GTEX Portal (Tissue expression)RCC2
Human Protein AtlasENSG00000179051-RCC2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P258   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9P258  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P258
PhosPhoSitePlusQ9P258
Domaine pattern : Prosite (Expaxy)RCC1_2 (PS00626)    RCC1_3 (PS50012)   
Domains : Interpro (EBI)RCC1/BLIP-II    RCC2    Reg_chr_condens   
Domain families : Pfam (Sanger)RCC1 (PF00415)   
Domain families : Pfam (NCBI)pfam00415   
Conserved Domain (NCBI)RCC2
PDB (RSDB)5GWN   
PDB Europe5GWN   
PDB (PDBSum)5GWN   
PDB (IMB)5GWN   
Structural Biology KnowledgeBase5GWN   
SCOP (Structural Classification of Proteins)5GWN   
CATH (Classification of proteins structures)5GWN   
SuperfamilyQ9P258
AlphaFold pdb e-kbQ9P258   
Human Protein Atlas [tissue]ENSG00000179051-RCC2 [tissue]
HPRD18171
Protein Interaction databases
DIP (DOE-UCLA)Q9P258
IntAct (EBI)Q9P258
BioGRIDRCC2
STRING (EMBL)RCC2
ZODIACRCC2
Ontologies - Pathways
QuickGOQ9P258
Ontology : AmiGORNA binding  guanyl-nucleotide exchange factor activity  protein binding  nucleolus  cytosol  microtubule  plasma membrane  mitotic spindle organization  integrin-mediated signaling pathway  microtubule binding  regulation of fibroblast migration  positive regulation of G2/M transition of mitotic cell cycle  membrane  protein kinase binding  protein domain specific binding  regulation of cell migration  midbody  small GTPase binding  early endosome membrane  negative regulation of GTPase activity  negative regulation of GTPase activity  chromosome, centromeric core domain  establishment of protein localization  focal adhesion assembly  cell division  negative regulation of focal adhesion assembly  positive regulation of attachment of spindle microtubules to kinetochore  chromosome passenger complex localization to kinetochore  activation of GTPase activity  negative regulation of substrate adhesion-dependent cell spreading  regulation of ruffle assembly  mitotic spindle midzone  
Ontology : EGO-EBIRNA binding  guanyl-nucleotide exchange factor activity  protein binding  nucleolus  cytosol  microtubule  plasma membrane  mitotic spindle organization  integrin-mediated signaling pathway  microtubule binding  regulation of fibroblast migration  positive regulation of G2/M transition of mitotic cell cycle  membrane  protein kinase binding  protein domain specific binding  regulation of cell migration  midbody  small GTPase binding  early endosome membrane  negative regulation of GTPase activity  negative regulation of GTPase activity  chromosome, centromeric core domain  establishment of protein localization  focal adhesion assembly  cell division  negative regulation of focal adhesion assembly  positive regulation of attachment of spindle microtubules to kinetochore  chromosome passenger complex localization to kinetochore  activation of GTPase activity  negative regulation of substrate adhesion-dependent cell spreading  regulation of ruffle assembly  mitotic spindle midzone  
NDEx NetworkRCC2
Atlas of Cancer Signalling NetworkRCC2
Wikipedia pathwaysRCC2
Orthology - Evolution
OrthoDB55920
GeneTree (enSembl)ENSG00000179051
Phylogenetic Trees/Animal Genes : TreeFamRCC2
Homologs : HomoloGeneRCC2
Homology/Alignments : Family Browser (UCSC)RCC2
Gene fusions - Rearrangements
Fusion : MitelmanMINOS1/RCC2 [1p36.13/1p36.13]  
Fusion : MitelmanRCC2/PADI4 [1p36.13/1p36.13]  
Fusion : QuiverRCC2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRCC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RCC2
dbVarRCC2
ClinVarRCC2
MonarchRCC2
1000_GenomesRCC2 
Exome Variant ServerRCC2
GNOMAD BrowserENSG00000179051
Varsome BrowserRCC2
ACMGRCC2 variants
VarityQ9P258
Genomic Variants (DGV)RCC2 [DGVbeta]
DECIPHERRCC2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRCC2 
Mutations
ICGC Data PortalRCC2 
TCGA Data PortalRCC2 
Broad Tumor PortalRCC2
OASIS PortalRCC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRCC2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRCC2
Mutations and Diseases : HGMDRCC2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaRCC2
DgiDB (Drug Gene Interaction Database)RCC2
DoCM (Curated mutations)RCC2
CIViC (Clinical Interpretations of Variants in Cancer)RCC2
Cancer3DRCC2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609587   
Orphanet
DisGeNETRCC2
MedgenRCC2
Genetic Testing Registry RCC2
NextProtQ9P258 [Medical]
GENETestsRCC2
Target ValidationRCC2
Huge Navigator RCC2 [HugePedia]
ClinGenRCC2
Clinical trials, drugs, therapy
MyCancerGenomeRCC2
Protein Interactions : CTDRCC2
Pharm GKB GenePA142671091
PharosQ9P258
Clinical trialRCC2
Miscellaneous
canSAR (ICR)RCC2
HarmonizomeRCC2
DataMed IndexRCC2
Probes
Litterature
PubMed98 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRCC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:28:34 CEST 2021

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