Atlas of Genetics and Cytogenetics in Oncology and Haematology


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RCOR1 (REST corepressor 1)

Identity

Alias_namesRCOR
REST corepressor
Alias_symbol (synonym)COREST
KIAA0071
Other alias
HGNC (Hugo) RCOR1
LocusID (NCBI) 23186
Atlas_Id 54578
Location 14q32.31  [Link to chromosome band 14q32]
Location_base_pair Starts at 102592659 and ends at 102730576 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CSF1R (5q32) / RCOR1 (14q32.31)RCOR1 (14q32.31) / EVL (14q32.2)RCOR1 (14q32.31) / KIT (4q12)
RCOR1 (14q32.31) / LMNA (1q22)RCOR1 (14q32.31) / PPM1E (17q22)RCOR1 (14q32.31) / PPP2R5C (14q32.31)
RCOR1 (14q32.31) / RCOR1 (14q32.31)RCOR1 (14q32.31) / TECPR2 (14q32.31)RCOR1 (14q32.31) / WDR70 (5p13.2)
TRAF3 (14q32.32) / RCOR1 (14q32.31)XPC (3p25.1) / RCOR1 (14q32.31)RCOR1 14q32.31 / KIT 4q12
RCOR1 14q32.31 / PPP2R5C 14q32.31RCOR1 14q32.31 / TECPR2 14q32.31TRAF3 14q32.32 / RCOR1 14q32.31
XPC 3p25.1 / RCOR1 14q32.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RCOR1   17441
Cards
Entrez_Gene (NCBI)RCOR1  23186  REST corepressor 1
AliasesCOREST; RCOR
GeneCards (Weizmann)RCOR1
Ensembl hg19 (Hinxton)ENSG00000089902 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000089902 [Gene_View]  chr14:102592659-102730576 [Contig_View]  RCOR1 [Vega]
ICGC DataPortalENSG00000089902
TCGA cBioPortalRCOR1
AceView (NCBI)RCOR1
Genatlas (Paris)RCOR1
WikiGenes23186
SOURCE (Princeton)RCOR1
Genetics Home Reference (NIH)RCOR1
Genomic and cartography
GoldenPath hg38 (UCSC)RCOR1  -     chr14:102592659-102730576 +  14q32.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RCOR1  -     14q32.31   [Description]    (hg19-Feb_2009)
EnsemblRCOR1 - 14q32.31 [CytoView hg19]  RCOR1 - 14q32.31 [CytoView hg38]
Mapping of homologs : NCBIRCOR1 [Mapview hg19]  RCOR1 [Mapview hg38]
OMIM607675   
Gene and transcription
Genbank (Entrez)AF070627 AF155595 AI337324 AK026612 BC051003
RefSeq transcript (Entrez)NM_015156
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RCOR1
Cluster EST : UnigeneHs.510521 [ NCBI ]
CGAP (NCI)Hs.510521
Alternative Splicing GalleryENSG00000089902
Gene ExpressionRCOR1 [ NCBI-GEO ]   RCOR1 [ EBI - ARRAY_EXPRESS ]   RCOR1 [ SEEK ]   RCOR1 [ MEM ]
Gene Expression Viewer (FireBrowse)RCOR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23186
GTEX Portal (Tissue expression)RCOR1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UKL0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UKL0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UKL0
Splice isoforms : SwissVarQ9UKL0
PhosPhoSitePlusQ9UKL0
Domaine pattern : Prosite (Expaxy)ELM2 (PS51156)    SANT (PS51293)   
Domains : Interpro (EBI)ELM2_dom    Homeobox-like    SANT/Myb    SANT_dom   
Domain families : Pfam (Sanger)ELM2 (PF01448)    Myb_DNA-binding (PF00249)   
Domain families : Pfam (NCBI)pfam01448    pfam00249   
Domain families : Smart (EMBL)ELM2 (SM01189)  SANT (SM00717)  
Conserved Domain (NCBI)RCOR1
DMDM Disease mutations23186
Blocks (Seattle)RCOR1
PDB (SRS)2IW5    2UXN    2UXX    2V1D    2X0L    2XAF    2XAG    2XAH    2XAJ    2XAQ    2XAS    2Y48    3ZMS    3ZMT    3ZMU    3ZMV    3ZMZ    3ZN0    3ZN1    4BAY    4KUM    4UV8    4UV9    4UVA    4UVB    4UVC    4UXN    4XBF    5L3B    5L3C    5L3D    5L3E    5L3F    5L3G    5LBQ   
PDB (PDBSum)2IW5    2UXN    2UXX    2V1D    2X0L    2XAF    2XAG    2XAH    2XAJ    2XAQ    2XAS    2Y48    3ZMS    3ZMT    3ZMU    3ZMV    3ZMZ    3ZN0    3ZN1    4BAY    4KUM    4UV8    4UV9    4UVA    4UVB    4UVC    4UXN    4XBF    5L3B    5L3C    5L3D    5L3E    5L3F    5L3G    5LBQ   
PDB (IMB)2IW5    2UXN    2UXX    2V1D    2X0L    2XAF    2XAG    2XAH    2XAJ    2XAQ    2XAS    2Y48    3ZMS    3ZMT    3ZMU    3ZMV    3ZMZ    3ZN0    3ZN1    4BAY    4KUM    4UV8    4UV9    4UVA    4UVB    4UVC    4UXN    4XBF    5L3B    5L3C    5L3D    5L3E    5L3F    5L3G    5LBQ   
PDB (RSDB)2IW5    2UXN    2UXX    2V1D    2X0L    2XAF    2XAG    2XAH    2XAJ    2XAQ    2XAS    2Y48    3ZMS    3ZMT    3ZMU    3ZMV    3ZMZ    3ZN0    3ZN1    4BAY    4KUM    4UV8    4UV9    4UVA    4UVB    4UVC    4UXN    4XBF    5L3B    5L3C    5L3D    5L3E    5L3F    5L3G    5LBQ   
Structural Biology KnowledgeBase2IW5    2UXN    2UXX    2V1D    2X0L    2XAF    2XAG    2XAH    2XAJ    2XAQ    2XAS    2Y48    3ZMS    3ZMT    3ZMU    3ZMV    3ZMZ    3ZN0    3ZN1    4BAY    4KUM    4UV8    4UV9    4UVA    4UVB    4UVC    4UXN    4XBF    5L3B    5L3C    5L3D    5L3E    5L3F    5L3G    5LBQ   
SCOP (Structural Classification of Proteins)2IW5    2UXN    2UXX    2V1D    2X0L    2XAF    2XAG    2XAH    2XAJ    2XAQ    2XAS    2Y48    3ZMS    3ZMT    3ZMU    3ZMV    3ZMZ    3ZN0    3ZN1    4BAY    4KUM    4UV8    4UV9    4UVA    4UVB    4UVC    4UXN    4XBF    5L3B    5L3C    5L3D    5L3E    5L3F    5L3G    5LBQ   
CATH (Classification of proteins structures)2IW5    2UXN    2UXX    2V1D    2X0L    2XAF    2XAG    2XAH    2XAJ    2XAQ    2XAS    2Y48    3ZMS    3ZMT    3ZMU    3ZMV    3ZMZ    3ZN0    3ZN1    4BAY    4KUM    4UV8    4UV9    4UVA    4UVB    4UVC    4UXN    4XBF    5L3B    5L3C    5L3D    5L3E    5L3F    5L3G    5LBQ   
SuperfamilyQ9UKL0
Human Protein AtlasENSG00000089902
Peptide AtlasQ9UKL0
HPRD09645
IPIIPI00008531   
Protein Interaction databases
DIP (DOE-UCLA)Q9UKL0
IntAct (EBI)Q9UKL0
FunCoupENSG00000089902
BioGRIDRCOR1
STRING (EMBL)RCOR1
ZODIACRCOR1
Ontologies - Pathways
QuickGOQ9UKL0
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcription corepressor activity  histone deacetylase activity  protein binding  nucleus  nucleus  nucleoplasm  transcription factor complex  transcription, DNA-templated  blood coagulation  transcription factor binding  viral process  transcriptional repressor complex  transcription regulatory region DNA binding  negative regulation of transcription, DNA-templated  histone H4 deacetylation  DNA repair complex  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcription corepressor activity  histone deacetylase activity  protein binding  nucleus  nucleus  nucleoplasm  transcription factor complex  transcription, DNA-templated  blood coagulation  transcription factor binding  viral process  transcriptional repressor complex  transcription regulatory region DNA binding  negative regulation of transcription, DNA-templated  histone H4 deacetylation  DNA repair complex  
Pathways : KEGGHuntington's disease   
NDEx NetworkRCOR1
Atlas of Cancer Signalling NetworkRCOR1
Wikipedia pathwaysRCOR1
Orthology - Evolution
OrthoDB23186
GeneTree (enSembl)ENSG00000089902
Phylogenetic Trees/Animal Genes : TreeFamRCOR1
HOVERGENQ9UKL0
HOGENOMQ9UKL0
Homologs : HomoloGeneRCOR1
Homology/Alignments : Family Browser (UCSC)RCOR1
Gene fusions - Rearrangements
Fusion : MitelmanRCOR1/KIT [14q32.31/4q12]  
Fusion : MitelmanRCOR1/PPP2R5C [14q32.31/14q32.31]  [t(14;14)(q32;q32)]  
Fusion : MitelmanRCOR1/TECPR2 [14q32.31/14q32.31]  [t(14;14)(q32;q32)]  
Fusion : MitelmanRCOR1/WDR70 [14q32.31/5p13.2]  [t(5;14)(p13;q32)]  
Fusion : MitelmanTRAF3/RCOR1 [14q32.32/14q32.31]  [t(14;14)(q32;q32)]  
Fusion : MitelmanXPC/RCOR1 [3p25.1/14q32.31]  [t(3;14)(p25;q32)]  
Fusion: TCGARCOR1 14q32.31 KIT 4q12 PRAD
Fusion: TCGARCOR1 14q32.31 PPP2R5C 14q32.31 OV
Fusion: TCGARCOR1 14q32.31 TECPR2 14q32.31 BLCA
Fusion: TCGATRAF3 14q32.32 RCOR1 14q32.31 BRCA
Fusion: TCGAXPC 3p25.1 RCOR1 14q32.31 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRCOR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RCOR1
dbVarRCOR1
ClinVarRCOR1
1000_GenomesRCOR1 
Exome Variant ServerRCOR1
ExAC (Exome Aggregation Consortium)RCOR1 (select the gene name)
Genetic variants : HAPMAP23186
Genomic Variants (DGV)RCOR1 [DGVbeta]
DECIPHERRCOR1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRCOR1 
Mutations
ICGC Data PortalRCOR1 
TCGA Data PortalRCOR1 
Broad Tumor PortalRCOR1
OASIS PortalRCOR1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRCOR1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRCOR1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RCOR1
DgiDB (Drug Gene Interaction Database)RCOR1
DoCM (Curated mutations)RCOR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RCOR1 (select a term)
intoGenRCOR1
Cancer3DRCOR1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607675   
Orphanet
MedgenRCOR1
Genetic Testing Registry RCOR1
NextProtQ9UKL0 [Medical]
TSGene23186
GENETestsRCOR1
Target ValidationRCOR1
Huge Navigator RCOR1 [HugePedia]
snp3D : Map Gene to Disease23186
BioCentury BCIQRCOR1
ClinGenRCOR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23186
Chemical/Pharm GKB GenePA34305
Clinical trialRCOR1
Miscellaneous
canSAR (ICR)RCOR1 (select the gene name)
Probes
Litterature
PubMed89 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRCOR1
EVEXRCOR1
GoPubMedRCOR1
iHOPRCOR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:52:53 CEST 2017

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