RCVRN (recoverin)

2003-02-01  

Identity

HGNC
RCVRN
LOCATION
17p13.1
LOCUSID
5957
ALIAS
RCV1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 5957
MIM: 179618
HGNC: 9937
Ensembl: ENSG00000109047

Variants:

dbSNP: 5957
ClinVar: 5957
TCGA: ENSG00000109047
COSMIC: RCVRN

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000109047ENST00000226193P35243

Expression (GTEx)

0
1
2
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
PhototransductionKEGGko04744
PhototransductionKEGGhsa04744
Signal TransductionREACTOMER-HSA-162582
Visual phototransductionREACTOMER-HSA-2187338
The phototransduction cascadeREACTOMER-HSA-2514856
Inactivation, recovery and regulation of the phototransduction cascadeREACTOMER-HSA-2514859

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
retina
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
213441772012Oxidation mimicking substitution of conservative cysteine in recoverin suppresses its membrane association.14
125969182002Pathological roles of recoverin in cancer-associated retinopathy.6
268135652016The cancer-retina antigen recoverin as a potential biomarker for renal tumors.6
182668172008Amino acid residues in GRK1/GRK7 responsible for interaction with S-modulin/recoverin.4
208129672010Aberrant demethylation of the recoverin gene is involved in the aberrant expression of recoverin in cancer cells.4
127895332003Functional analysis of the human recoverin gene promoter.2
173744192007Establishment of a novel small cell lung carcinoma cell line with specific recoverin expression from a patient with cancer-associated retinopathy.1
265840242015Crystal Structure of Recoverin with Calcium Ions Bound to Both Functional EF Hands.1
316586392019Effects of Membrane and Biological Target on the Structural and Allosteric Properties of Recoverin: A Computational Approach.1
312884442019Experimental Insight into the Structural and Functional Roles of the 'Black' and 'Gray' Clusters in Recoverin, a Calcium Binding Protein with Four EF-Hand Motifs.0

Citation

Dessen P

RCVRN (recoverin)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42079/rcvrn