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RDH10 (retinol dehydrogenase 10)

Identity

Alias_namesmember 4
Alias_symbol (synonym)SDR16C4
Other alias
HGNC (Hugo) RDH10
LocusID (NCBI) 157506
Atlas_Id 49788
Location 8q21.11  [Link to chromosome band 8q21]
Location_base_pair Starts at 73294602 and ends at 73325285 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
JA040725 () / RDH10 (8q21.11)NEDD4 (15q21.3) / RDH10 (8q21.11)RDH10 (8q21.11) / NEDD4 (15q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)RDH10   19975
Cards
Entrez_Gene (NCBI)RDH10  157506  retinol dehydrogenase 10
AliasesSDR16C4
GeneCards (Weizmann)RDH10
Ensembl hg19 (Hinxton)ENSG00000121039 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000121039 [Gene_View]  chr8:73294602-73325285 [Contig_View]  RDH10 [Vega]
ICGC DataPortalENSG00000121039
TCGA cBioPortalRDH10
AceView (NCBI)RDH10
Genatlas (Paris)RDH10
WikiGenes157506
SOURCE (Princeton)RDH10
Genetics Home Reference (NIH)RDH10
Genomic and cartography
GoldenPath hg38 (UCSC)RDH10  -     chr8:73294602-73325285 +  8q21.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RDH10  -     8q21.11   [Description]    (hg19-Feb_2009)
EnsemblRDH10 - 8q21.11 [CytoView hg19]  RDH10 - 8q21.11 [CytoView hg38]
Mapping of homologs : NCBIRDH10 [Mapview hg19]  RDH10 [Mapview hg38]
OMIM607599   
Gene and transcription
Genbank (Entrez)AF456765 AY358270 BC067131 BM472905 BM804062
RefSeq transcript (Entrez)NM_172037
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RDH10
Cluster EST : UnigeneHs.244940 [ NCBI ]
CGAP (NCI)Hs.244940
Alternative Splicing GalleryENSG00000121039
Gene ExpressionRDH10 [ NCBI-GEO ]   RDH10 [ EBI - ARRAY_EXPRESS ]   RDH10 [ SEEK ]   RDH10 [ MEM ]
Gene Expression Viewer (FireBrowse)RDH10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)157506
GTEX Portal (Tissue expression)RDH10
Human Protein AtlasENSG00000121039-RDH10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IZV5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IZV5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IZV5
Splice isoforms : SwissVarQ8IZV5
Catalytic activity : Enzyme1.1.1.300 [ Enzyme-Expasy ]   1.1.1.3001.1.1.300 [ IntEnz-EBI ]   1.1.1.300 [ BRENDA ]   1.1.1.300 [ KEGG ]   
PhosPhoSitePlusQ8IZV5
Domaine pattern : Prosite (Expaxy)ADH_SHORT (PS00061)   
Domains : Interpro (EBI)NAD(P)-bd_dom    RDH10    Sc_DH/Rdtase_CS    SDR_fam   
Domain families : Pfam (Sanger)adh_short (PF00106)   
Domain families : Pfam (NCBI)pfam00106   
Conserved Domain (NCBI)RDH10
DMDM Disease mutations157506
Blocks (Seattle)RDH10
SuperfamilyQ8IZV5
Human Protein Atlas [tissue]ENSG00000121039-RDH10 [tissue]
Peptide AtlasQ8IZV5
HPRD07605
IPIIPI00218086   IPI00981424   IPI00982065   
Protein Interaction databases
DIP (DOE-UCLA)Q8IZV5
IntAct (EBI)Q8IZV5
FunCoupENSG00000121039
BioGRIDRDH10
STRING (EMBL)RDH10
ZODIACRDH10
Ontologies - Pathways
QuickGOQ8IZV5
Ontology : AmiGOretinoid metabolic process  metanephros development  in utero embryonic development  retinoic acid biosynthetic process  retinol dehydrogenase activity  retinol dehydrogenase activity  nucleus  cytoplasm  endoplasmic reticulum membrane  visual perception  gonad development  neural crest cell development  integral component of membrane  embryonic camera-type eye development  organelle membrane  embryonic forelimb morphogenesis  retinol metabolic process  retinol metabolic process  retinal metabolic process  ear development  nose development  cell body  embryonic viscerocranium morphogenesis  NADP-retinol dehydrogenase activity  oxidation-reduction process  primary lung bud formation  bud elongation involved in lung branching  
Ontology : EGO-EBIretinoid metabolic process  metanephros development  in utero embryonic development  retinoic acid biosynthetic process  retinol dehydrogenase activity  retinol dehydrogenase activity  nucleus  cytoplasm  endoplasmic reticulum membrane  visual perception  gonad development  neural crest cell development  integral component of membrane  embryonic camera-type eye development  organelle membrane  embryonic forelimb morphogenesis  retinol metabolic process  retinol metabolic process  retinal metabolic process  ear development  nose development  cell body  embryonic viscerocranium morphogenesis  NADP-retinol dehydrogenase activity  oxidation-reduction process  primary lung bud formation  bud elongation involved in lung branching  
Pathways : KEGGRetinol metabolism   
NDEx NetworkRDH10
Atlas of Cancer Signalling NetworkRDH10
Wikipedia pathwaysRDH10
Orthology - Evolution
OrthoDB157506
GeneTree (enSembl)ENSG00000121039
Phylogenetic Trees/Animal Genes : TreeFamRDH10
HOVERGENQ8IZV5
HOGENOMQ8IZV5
Homologs : HomoloGeneRDH10
Homology/Alignments : Family Browser (UCSC)RDH10
Gene fusions - Rearrangements
Fusion : MitelmanNEDD4/RDH10 [15q21.3/8q21.11]  [t(8;15)(q21;q21)]  
Fusion : MitelmanRDH10/NEDD4 [8q21.11/15q21.3]  [t(8;15)(q21;q21)]  
Tumor Fusion PortalRDH10
Fusion Cancer (Beijing)JA040725 [RDH10]  -  8q21.11 [FUSC001195]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRDH10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RDH10
dbVarRDH10
ClinVarRDH10
1000_GenomesRDH10 
Exome Variant ServerRDH10
ExAC (Exome Aggregation Consortium)ENSG00000121039
GNOMAD BrowserENSG00000121039
Genetic variants : HAPMAP157506
Genomic Variants (DGV)RDH10 [DGVbeta]
DECIPHERRDH10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRDH10 
Mutations
ICGC Data PortalRDH10 
TCGA Data PortalRDH10 
Broad Tumor PortalRDH10
OASIS PortalRDH10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRDH10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRDH10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RDH10
DgiDB (Drug Gene Interaction Database)RDH10
DoCM (Curated mutations)RDH10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RDH10 (select a term)
intoGenRDH10
Cancer3DRDH10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607599   
Orphanet
DisGeNETRDH10
MedgenRDH10
Genetic Testing Registry RDH10
NextProtQ8IZV5 [Medical]
TSGene157506
GENETestsRDH10
Target ValidationRDH10
Huge Navigator RDH10 [HugePedia]
snp3D : Map Gene to Disease157506
BioCentury BCIQRDH10
ClinGenRDH10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD157506
Chemical/Pharm GKB GenePA134989620
Clinical trialRDH10
Miscellaneous
canSAR (ICR)RDH10 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRDH10
EVEXRDH10
GoPubMedRDH10
iHOPRDH10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:32:03 CET 2017

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