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RDH11 (retinol dehydrogenase 11 (all-trans/9-cis/11-cis))

Identity

Other namesARSDR1
CGI82
HCBP12
MDT1
PSDR1
RALR1
RDJCSS
SCALD
SDR7C1
HGNC (Hugo) RDH11
LocusID (NCBI) 51109
Atlas_Id 42080
Location 14q24.1  [Link to chromosome band 14q24]
Location_base_pair Starts at 68143519 and ends at 68162510 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CYCS (7p15.3) / RDH11 (14q24.1)E2F1 (20q11.22) / RDH11 (14q24.1)EPOR (19p13.2) / RDH11 (14q24.1)
HNRNPH3 (10q21.3) / RDH11 (14q24.1)KLK2 (19q13.33) / RDH11 (14q24.1)MPP5 (14q23.3) / RDH11 (14q24.1)
RDH11 (14q24.1) / IPO7 (11p15.4)RDH11 (14q24.1) / PRSS23 (11q14.2)VTI1B (14q24.1) / RDH11 (14q24.1)
MPP5 14q23.3 / RDH11 14q24.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RDH11   17964
Cards
Entrez_Gene (NCBI)RDH11  51109  retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
AliasesARSDR1; CGI82; HCBP12; MDT1; 
PSDR1; RALR1; RDJCSS; SCALD; SDR7C1
GeneCards (Weizmann)RDH11
Ensembl hg19 (Hinxton)ENSG00000072042 [Gene_View]  chr14:68143519-68162510 [Contig_View]  RDH11 [Vega]
Ensembl hg38 (Hinxton)ENSG00000072042 [Gene_View]  chr14:68143519-68162510 [Contig_View]  RDH11 [Vega]
ICGC DataPortalENSG00000072042
TCGA cBioPortalRDH11
AceView (NCBI)RDH11
Genatlas (Paris)RDH11
WikiGenes51109
SOURCE (Princeton)RDH11
Genomic and cartography
GoldenPath hg19 (UCSC)RDH11  -     chr14:68143519-68162510 -  14q24.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RDH11  -     14q24.1   [Description]    (hg38-Dec_2013)
EnsemblRDH11 - 14q24.1 [CytoView hg19]  RDH11 - 14q24.1 [CytoView hg38]
Mapping of homologs : NCBIRDH11 [Mapview hg19]  RDH11 [Mapview hg38]
OMIM607849   616108   
Gene and transcription
Genbank (Entrez)AB209223 AF151840 AF167438 AF395068 AI382141
RefSeq transcript (Entrez)NM_001252650 NM_016026
RefSeq genomic (Entrez)NC_000014 NC_018925 NG_042282 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)RDH11
Cluster EST : UnigeneHs.719925 [ NCBI ]
CGAP (NCI)Hs.719925
Alternative Splicing GalleryENSG00000072042
Gene ExpressionRDH11 [ NCBI-GEO ]   RDH11 [ EBI - ARRAY_EXPRESS ]   RDH11 [ SEEK ]   RDH11 [ MEM ]
Gene Expression Viewer (FireBrowse)RDH11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51109
GTEX Portal (Tissue expression)RDH11
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TC12 (Uniprot)
NextProtQ8TC12  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TC12
Splice isoforms : SwissVarQ8TC12 (Swissvar)
Catalytic activity : Enzyme1.1.1.300 [ Enzyme-Expasy ]   1.1.1.3001.1.1.300 [ IntEnz-EBI ]   1.1.1.300 [ BRENDA ]   1.1.1.300 [ KEGG ]   
PhosPhoSitePlusQ8TC12
Domains : Interpro (EBI)DH_sc/Rdtase_SDR    Glc/ribitol_DH    NAD(P)-bd_dom   
Domain families : Pfam (Sanger)adh_short (PF00106)   
Domain families : Pfam (NCBI)pfam00106   
DMDM Disease mutations51109
Blocks (Seattle)RDH11
SuperfamilyQ8TC12
Human Protein AtlasENSG00000072042
Peptide AtlasQ8TC12
HPRD09707
IPIIPI00339384   IPI00339385   IPI00910248   IPI00555948   IPI01025768   IPI01026108   IPI01026000   IPI01025203   IPI01025555   
Protein Interaction databases
DIP (DOE-UCLA)Q8TC12
IntAct (EBI)Q8TC12
FunCoupENSG00000072042
BioGRIDRDH11
STRING (EMBL)RDH11
ZODIACRDH11
Ontologies - Pathways
QuickGOQ8TC12
Ontology : AmiGOretinoid metabolic process  photoreceptor inner segment  retinol dehydrogenase activity  retinol dehydrogenase activity  intracellular  endoplasmic reticulum membrane  integral component of membrane  adaptation of rhodopsin mediated signaling  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor  retinol metabolic process  retinal metabolic process  NADP-retinol dehydrogenase activity  NADP-retinol dehydrogenase activity  oxidation-reduction process  
Ontology : EGO-EBIretinoid metabolic process  photoreceptor inner segment  retinol dehydrogenase activity  retinol dehydrogenase activity  intracellular  endoplasmic reticulum membrane  integral component of membrane  adaptation of rhodopsin mediated signaling  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor  retinol metabolic process  retinal metabolic process  NADP-retinol dehydrogenase activity  NADP-retinol dehydrogenase activity  oxidation-reduction process  
Pathways : KEGGRetinol metabolism   
NDEx NetworkRDH11
Atlas of Cancer Signalling NetworkRDH11
Wikipedia pathwaysRDH11
Orthology - Evolution
OrthoDB51109
GeneTree (enSembl)ENSG00000072042
Phylogenetic Trees/Animal Genes : TreeFamRDH11
Homologs : HomoloGeneRDH11
Homology/Alignments : Family Browser (UCSC)RDH11
Gene fusions - Rearrangements
Fusion: TCGAMPP5 14q23.3 RDH11 14q24.1 BRCA
Polymorphisms : SNP, variants
NCBI Variation ViewerRDH11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RDH11
dbVarRDH11
ClinVarRDH11
1000_GenomesRDH11 
Exome Variant ServerRDH11
ExAC (Exome Aggregation Consortium)RDH11 (select the gene name)
Genetic variants : HAPMAP51109
Genomic Variants (DGV)RDH11 [DGVbeta]
Mutations
ICGC Data PortalRDH11 
TCGA Data PortalRDH11 
Broad Tumor PortalRDH11
OASIS PortalRDH11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRDH11 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RDH11
DgiDB (Drug Gene Interaction Database)RDH11
DoCM (Curated mutations)RDH11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RDH11 (select a term)
intoGenRDH11
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)14:68143519-68162510  ENSG00000072042
CONAN: Copy Number AnalysisRDH11 
Mutations and Diseases : HGMDRDH11
OMIM607849    616108   
MedgenRDH11
Genetic Testing Registry RDH11
NextProtQ8TC12 [Medical]
TSGene51109
GENETestsRDH11
Huge Navigator RDH11 [HugePedia]
snp3D : Map Gene to Disease51109
BioCentury BCIQRDH11
ClinGenRDH11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51109
Chemical/Pharm GKB GenePA134981588
Clinical trialRDH11
Miscellaneous
canSAR (ICR)RDH11 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRDH11
EVEXRDH11
GoPubMedRDH11
iHOPRDH11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 19 19:10:29 CEST 2016

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