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RDH8 (retinol dehydrogenase 8 (all-trans))

Identity

Alias_symbol (synonym)PRRDH
SDR28C2
Other alias
HGNC (Hugo) RDH8
LocusID (NCBI) 50700
Atlas_Id 72566
Location 19p13.2  [Link to chromosome band 19p13]
Location_base_pair Starts at 10013249 and ends at 10022278 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ELOF1 (19p13.2) / RDH8 (19p13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RDH8   14423
Cards
Entrez_Gene (NCBI)RDH8  50700  retinol dehydrogenase 8 (all-trans)
AliasesPRRDH; SDR28C2
GeneCards (Weizmann)RDH8
Ensembl hg19 (Hinxton)ENSG00000080511 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000080511 [Gene_View]  chr19:10013249-10022278 [Contig_View]  RDH8 [Vega]
ICGC DataPortalENSG00000080511
TCGA cBioPortalRDH8
AceView (NCBI)RDH8
Genatlas (Paris)RDH8
WikiGenes50700
SOURCE (Princeton)RDH8
Genetics Home Reference (NIH)RDH8
Genomic and cartography
GoldenPath hg38 (UCSC)RDH8  -     chr19:10013249-10022278 +  19p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RDH8  -     19p13.2   [Description]    (hg19-Feb_2009)
EnsemblRDH8 - 19p13.2 [CytoView hg19]  RDH8 - 19p13.2 [CytoView hg38]
Mapping of homologs : NCBIRDH8 [Mapview hg19]  RDH8 [Mapview hg38]
OMIM608575   
Gene and transcription
Genbank (Entrez)AF229845 AK024022 BC140328 BC146479 DQ426888
RefSeq transcript (Entrez)NM_015725
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RDH8
Cluster EST : UnigeneHs.675522 [ NCBI ]
CGAP (NCI)Hs.675522
Alternative Splicing GalleryENSG00000080511
Gene ExpressionRDH8 [ NCBI-GEO ]   RDH8 [ EBI - ARRAY_EXPRESS ]   RDH8 [ SEEK ]   RDH8 [ MEM ]
Gene Expression Viewer (FireBrowse)RDH8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)50700
GTEX Portal (Tissue expression)RDH8
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NYR8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NYR8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NYR8
Splice isoforms : SwissVarQ9NYR8
Catalytic activity : Enzyme1.1.1.300 [ Enzyme-Expasy ]   1.1.1.3001.1.1.300 [ IntEnz-EBI ]   1.1.1.300 [ BRENDA ]   1.1.1.300 [ KEGG ]   
PhosPhoSitePlusQ9NYR8
Domaine pattern : Prosite (Expaxy)ADH_SHORT (PS00061)   
Domains : Interpro (EBI)17beta_DH    NAD(P)-bd_dom    Sc_DH/Rdtase_CS    SDR_fam   
Domain families : Pfam (Sanger)adh_short (PF00106)   
Domain families : Pfam (NCBI)pfam00106   
Conserved Domain (NCBI)RDH8
DMDM Disease mutations50700
Blocks (Seattle)RDH8
SuperfamilyQ9NYR8
Human Protein AtlasENSG00000080511
Peptide AtlasQ9NYR8
HPRD16350
IPIIPI00024598   
Protein Interaction databases
DIP (DOE-UCLA)Q9NYR8
IntAct (EBI)Q9NYR8
FunCoupENSG00000080511
BioGRIDRDH8
STRING (EMBL)RDH8
ZODIACRDH8
Ontologies - Pathways
QuickGOQ9NYR8
Ontology : AmiGOestradiol 17-beta-dehydrogenase activity  retinol dehydrogenase activity  cytoplasm  integral component of plasma membrane  steroid biosynthetic process  estrogen biosynthetic process  visual perception  retinol metabolic process  response to stimulus  NADP-retinol dehydrogenase activity  oxidation-reduction process  
Ontology : EGO-EBIestradiol 17-beta-dehydrogenase activity  retinol dehydrogenase activity  cytoplasm  integral component of plasma membrane  steroid biosynthetic process  estrogen biosynthetic process  visual perception  retinol metabolic process  response to stimulus  NADP-retinol dehydrogenase activity  oxidation-reduction process  
Pathways : KEGGRetinol metabolism   
NDEx NetworkRDH8
Atlas of Cancer Signalling NetworkRDH8
Wikipedia pathwaysRDH8
Orthology - Evolution
OrthoDB50700
GeneTree (enSembl)ENSG00000080511
Phylogenetic Trees/Animal Genes : TreeFamRDH8
HOVERGENQ9NYR8
HOGENOMQ9NYR8
Homologs : HomoloGeneRDH8
Homology/Alignments : Family Browser (UCSC)RDH8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRDH8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RDH8
dbVarRDH8
ClinVarRDH8
1000_GenomesRDH8 
Exome Variant ServerRDH8
ExAC (Exome Aggregation Consortium)RDH8 (select the gene name)
Genetic variants : HAPMAP50700
Genomic Variants (DGV)RDH8 [DGVbeta]
DECIPHERRDH8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRDH8 
Mutations
ICGC Data PortalRDH8 
TCGA Data PortalRDH8 
Broad Tumor PortalRDH8
OASIS PortalRDH8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRDH8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRDH8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RDH8
DgiDB (Drug Gene Interaction Database)RDH8
DoCM (Curated mutations)RDH8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RDH8 (select a term)
intoGenRDH8
Cancer3DRDH8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608575   
Orphanet
MedgenRDH8
Genetic Testing Registry RDH8
NextProtQ9NYR8 [Medical]
TSGene50700
GENETestsRDH8
Target ValidationRDH8
Huge Navigator RDH8 [HugePedia]
snp3D : Map Gene to Disease50700
BioCentury BCIQRDH8
ClinGenRDH8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD50700
Chemical/Pharm GKB GenePA34309
Clinical trialRDH8
Miscellaneous
canSAR (ICR)RDH8 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRDH8
EVEXRDH8
GoPubMedRDH8
iHOPRDH8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:38:27 CEST 2017

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