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RECK (reversion inducing cysteine rich protein with kazal motifs)

Identity

Alias_namesST15
Alias_symbol (synonym)hRECK
Other alias
HGNC (Hugo) RECK
LocusID (NCBI) 8434
Atlas_Id 42081
Location 9p13.3  [Link to chromosome band 9p13]
Location_base_pair Starts at 36036913 and ends at 36124455 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
RECK (9p13.3) / ALX3 (1p13.3)RECK (9p13.3) / TMEM8B (9p13.3)WSB1 (17q11.1) / RECK (9p13.3)
RECK 9p13.3 / TMEM8B 9p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RECK   11345
Cards
Entrez_Gene (NCBI)RECK  8434  reversion inducing cysteine rich protein with kazal motifs
AliasesST15
GeneCards (Weizmann)RECK
Ensembl hg19 (Hinxton)ENSG00000122707 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000122707 [Gene_View]  chr9:36036913-36124455 [Contig_View]  RECK [Vega]
ICGC DataPortalENSG00000122707
TCGA cBioPortalRECK
AceView (NCBI)RECK
Genatlas (Paris)RECK
WikiGenes8434
SOURCE (Princeton)RECK
Genetics Home Reference (NIH)RECK
Genomic and cartography
GoldenPath hg38 (UCSC)RECK  -     chr9:36036913-36124455 +  9p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RECK  -     9p13.3   [Description]    (hg19-Feb_2009)
EnsemblRECK - 9p13.3 [CytoView hg19]  RECK - 9p13.3 [CytoView hg38]
Mapping of homologs : NCBIRECK [Mapview hg19]  RECK [Mapview hg38]
OMIM605227   
Gene and transcription
Genbank (Entrez)AF086228 AK022897 AK292653 AK315073 BC032240
RefSeq transcript (Entrez)NM_001316345 NM_001316346 NM_001316347 NM_001316348 NM_021111
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RECK
Cluster EST : UnigeneHs.388918 [ NCBI ]
CGAP (NCI)Hs.388918
Alternative Splicing GalleryENSG00000122707
Gene ExpressionRECK [ NCBI-GEO ]   RECK [ EBI - ARRAY_EXPRESS ]   RECK [ SEEK ]   RECK [ MEM ]
Gene Expression Viewer (FireBrowse)RECK [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8434
GTEX Portal (Tissue expression)RECK
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95980   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95980  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95980
Splice isoforms : SwissVarO95980
PhosPhoSitePlusO95980
Domaine pattern : Prosite (Expaxy)KAZAL_1 (PS00282)    KAZAL_2 (PS51465)   
Domains : Interpro (EBI)Kazal_dom   
Domain families : Pfam (Sanger)Kazal_2 (PF07648)   
Domain families : Pfam (NCBI)pfam07648   
Domain families : Smart (EMBL)KAZAL (SM00280)  
Conserved Domain (NCBI)RECK
DMDM Disease mutations8434
Blocks (Seattle)RECK
SuperfamilyO95980
Human Protein AtlasENSG00000122707
Peptide AtlasO95980
HPRD05567
IPIIPI00028082   IPI00844242   
Protein Interaction databases
DIP (DOE-UCLA)O95980
IntAct (EBI)O95980
FunCoupENSG00000122707
BioGRIDRECK
STRING (EMBL)RECK
ZODIACRECK
Ontologies - Pathways
QuickGOO95980
Ontology : AmiGOblood vessel maturation  endopeptidase inhibitor activity  serine-type endopeptidase inhibitor activity  protein binding  extracellular region  plasma membrane  plasma membrane  C-terminal protein lipidation  embryo implantation  metalloendopeptidase inhibitor activity  membrane  extracellular matrix organization  negative regulation of cell migration  anchored component of membrane  embryonic forelimb morphogenesis  negative regulation of metalloendopeptidase activity  
Ontology : EGO-EBIblood vessel maturation  endopeptidase inhibitor activity  serine-type endopeptidase inhibitor activity  protein binding  extracellular region  plasma membrane  plasma membrane  C-terminal protein lipidation  embryo implantation  metalloendopeptidase inhibitor activity  membrane  extracellular matrix organization  negative regulation of cell migration  anchored component of membrane  embryonic forelimb morphogenesis  negative regulation of metalloendopeptidase activity  
Pathways : BIOCARTAInhibition of Matrix Metalloproteinases [Genes]   
Pathways : KEGGMicroRNAs in cancer   
NDEx NetworkRECK
Atlas of Cancer Signalling NetworkRECK
Wikipedia pathwaysRECK
Orthology - Evolution
OrthoDB8434
GeneTree (enSembl)ENSG00000122707
Phylogenetic Trees/Animal Genes : TreeFamRECK
HOVERGENO95980
HOGENOMO95980
Homologs : HomoloGeneRECK
Homology/Alignments : Family Browser (UCSC)RECK
Gene fusions - Rearrangements
Fusion : MitelmanRECK/ALX3 [9p13.3/1p13.3]  
Fusion : MitelmanRECK/TMEM8B [9p13.3/9p13.3]  [t(9;9)(p13;p13)]  
Fusion: TCGARECK 9p13.3 TMEM8B 9p13.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRECK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RECK
dbVarRECK
ClinVarRECK
1000_GenomesRECK 
Exome Variant ServerRECK
ExAC (Exome Aggregation Consortium)RECK (select the gene name)
Genetic variants : HAPMAP8434
Genomic Variants (DGV)RECK [DGVbeta]
DECIPHERRECK [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRECK 
Mutations
ICGC Data PortalRECK 
TCGA Data PortalRECK 
Broad Tumor PortalRECK
OASIS PortalRECK [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRECK  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRECK
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RECK
DgiDB (Drug Gene Interaction Database)RECK
DoCM (Curated mutations)RECK (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RECK (select a term)
intoGenRECK
Cancer3DRECK(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605227   
Orphanet
MedgenRECK
Genetic Testing Registry RECK
NextProtO95980 [Medical]
TSGene8434
GENETestsRECK
Target ValidationRECK
Huge Navigator RECK [HugePedia]
snp3D : Map Gene to Disease8434
BioCentury BCIQRECK
ClinGenRECK
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8434
Chemical/Pharm GKB GenePA34314
Clinical trialRECK
Miscellaneous
canSAR (ICR)RECK (select the gene name)
Probes
Litterature
PubMed127 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRECK
EVEXRECK
GoPubMedRECK
iHOPRECK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:12:49 CEST 2017

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