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REG1A (regenerating family member 1 alpha)

Identity

Alias_namesREG
regenerating islet-derived 1 alpha (pancreatic stone protein
Alias_symbol (synonym)PSP
PTP
PSPS
PSPS1
Other aliasICRF
P19
HGNC (Hugo) REG1A
LocusID (NCBI) 5967
Atlas_Id 53311
Location 2p12  [Link to chromosome band 2p12]
Location_base_pair Starts at 79120458 and ends at 79123419 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GNA11 (19p13.3) / REG1A (2p12)REG1A (2p12) / GNA11 (19p13.3)REG1A (2p12) / REG1A (2p12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)REG1A   9951
Cards
Entrez_Gene (NCBI)REG1A  5967  regenerating family member 1 alpha
AliasesICRF; P19; PSP; PSPS; 
PSPS1; PTP; REG
GeneCards (Weizmann)REG1A
Ensembl hg19 (Hinxton)ENSG00000115386 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115386 [Gene_View]  chr2:79120458-79123419 [Contig_View]  REG1A [Vega]
ICGC DataPortalENSG00000115386
TCGA cBioPortalREG1A
AceView (NCBI)REG1A
Genatlas (Paris)REG1A
WikiGenes5967
SOURCE (Princeton)REG1A
Genetics Home Reference (NIH)REG1A
Genomic and cartography
GoldenPath hg38 (UCSC)REG1A  -     chr2:79120458-79123419 +  2p12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)REG1A  -     2p12   [Description]    (hg19-Feb_2009)
EnsemblREG1A - 2p12 [CytoView hg19]  REG1A - 2p12 [CytoView hg38]
Mapping of homologs : NCBIREG1A [Mapview hg19]  REG1A [Mapview hg38]
OMIM167770   
Gene and transcription
Genbank (Entrez)AF172331 AK291981 AK307292 AK311087 AW873911
RefSeq transcript (Entrez)NM_002909
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)REG1A
Cluster EST : UnigeneHs.49407 [ NCBI ]
CGAP (NCI)Hs.49407
Alternative Splicing GalleryENSG00000115386
Gene ExpressionREG1A [ NCBI-GEO ]   REG1A [ EBI - ARRAY_EXPRESS ]   REG1A [ SEEK ]   REG1A [ MEM ]
Gene Expression Viewer (FireBrowse)REG1A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5967
GTEX Portal (Tissue expression)REG1A
Protein : pattern, domain, 3D structure
UniProt/SwissProtP05451   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP05451  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP05451
Splice isoforms : SwissVarP05451
PhosPhoSitePlusP05451
Domaine pattern : Prosite (Expaxy)C_TYPE_LECTIN_1 (PS00615)    C_TYPE_LECTIN_2 (PS50041)   
Domains : Interpro (EBI)C-type_lectin-like    C-type_lectin-like/link    C-type_lectin_CS    CTDL_fold   
Domain families : Pfam (Sanger)Lectin_C (PF00059)   
Domain families : Pfam (NCBI)pfam00059   
Domain families : Smart (EMBL)CLECT (SM00034)  
Conserved Domain (NCBI)REG1A
DMDM Disease mutations5967
Blocks (Seattle)REG1A
PDB (SRS)1LIT    1QDD   
PDB (PDBSum)1LIT    1QDD   
PDB (IMB)1LIT    1QDD   
PDB (RSDB)1LIT    1QDD   
Structural Biology KnowledgeBase1LIT    1QDD   
SCOP (Structural Classification of Proteins)1LIT    1QDD   
CATH (Classification of proteins structures)1LIT    1QDD   
SuperfamilyP05451
Human Protein AtlasENSG00000115386
Peptide AtlasP05451
HPRD01338
IPIIPI00009027   
Protein Interaction databases
DIP (DOE-UCLA)P05451
IntAct (EBI)P05451
FunCoupENSG00000115386
BioGRIDREG1A
STRING (EMBL)REG1A
ZODIACREG1A
Ontologies - Pathways
QuickGOP05451
Ontology : AmiGOgrowth factor activity  positive regulation of cell proliferation  carbohydrate binding  extracellular exosome  
Ontology : EGO-EBIgrowth factor activity  positive regulation of cell proliferation  carbohydrate binding  extracellular exosome  
NDEx NetworkREG1A
Atlas of Cancer Signalling NetworkREG1A
Wikipedia pathwaysREG1A
Orthology - Evolution
OrthoDB5967
GeneTree (enSembl)ENSG00000115386
Phylogenetic Trees/Animal Genes : TreeFamREG1A
HOVERGENP05451
HOGENOMP05451
Homologs : HomoloGeneREG1A
Homology/Alignments : Family Browser (UCSC)REG1A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerREG1A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)REG1A
dbVarREG1A
ClinVarREG1A
1000_GenomesREG1A 
Exome Variant ServerREG1A
ExAC (Exome Aggregation Consortium)REG1A (select the gene name)
Genetic variants : HAPMAP5967
Genomic Variants (DGV)REG1A [DGVbeta]
DECIPHERREG1A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisREG1A 
Mutations
ICGC Data PortalREG1A 
TCGA Data PortalREG1A 
Broad Tumor PortalREG1A
OASIS PortalREG1A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICREG1A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDREG1A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch REG1A
DgiDB (Drug Gene Interaction Database)REG1A
DoCM (Curated mutations)REG1A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)REG1A (select a term)
intoGenREG1A
Cancer3DREG1A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM167770   
Orphanet
MedgenREG1A
Genetic Testing Registry REG1A
NextProtP05451 [Medical]
TSGene5967
GENETestsREG1A
Target ValidationREG1A
Huge Navigator REG1A [HugePedia]
snp3D : Map Gene to Disease5967
BioCentury BCIQREG1A
ClinGenREG1A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5967
Chemical/Pharm GKB GenePA34318
Clinical trialREG1A
Miscellaneous
canSAR (ICR)REG1A (select the gene name)
Probes
Litterature
PubMed86 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineREG1A
EVEXREG1A
GoPubMedREG1A
iHOPREG1A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:28:28 CEST 2017

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