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REM2 (RRAD and GEM like GTPase 2)

Identity

Alias_namesRAS (RAD and GEM) like GTP binding 2
Alias_symbol (synonym)FLJ38964
Other alias-
HGNC (Hugo) REM2
LocusID (NCBI) 161253
Atlas_Id 43267
Location 14q11.2  [Link to chromosome band 14q11]
Location_base_pair Starts at 22883223 and ends at 22887680 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LRP10 (14q11.2) / REM2 (14q11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)REM2   20248
Cards
Entrez_Gene (NCBI)REM2  161253  RRAD and GEM like GTPase 2
Aliases
GeneCards (Weizmann)REM2
Ensembl hg19 (Hinxton)ENSG00000139890 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000139890 [Gene_View]  chr14:22883223-22887680 [Contig_View]  REM2 [Vega]
ICGC DataPortalENSG00000139890
TCGA cBioPortalREM2
AceView (NCBI)REM2
Genatlas (Paris)REM2
WikiGenes161253
SOURCE (Princeton)REM2
Genetics Home Reference (NIH)REM2
Genomic and cartography
GoldenPath hg38 (UCSC)REM2  -     chr14:22883223-22887680 +  14q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)REM2  -     14q11.2   [Description]    (hg19-Feb_2009)
EnsemblREM2 - 14q11.2 [CytoView hg19]  REM2 - 14q11.2 [CytoView hg38]
Mapping of homologs : NCBIREM2 [Mapview hg19]  REM2 [Mapview hg38]
OMIM616955   
Gene and transcription
Genbank (Entrez)AK096283 AK299238 BC035663 KU178879 KU178880
RefSeq transcript (Entrez)NM_173527
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)REM2
Cluster EST : UnigeneHs.444911 [ NCBI ]
CGAP (NCI)Hs.444911
Alternative Splicing GalleryENSG00000139890
Gene ExpressionREM2 [ NCBI-GEO ]   REM2 [ EBI - ARRAY_EXPRESS ]   REM2 [ SEEK ]   REM2 [ MEM ]
Gene Expression Viewer (FireBrowse)REM2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)161253
GTEX Portal (Tissue expression)REM2
Human Protein AtlasENSG00000139890-REM2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IYK8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IYK8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IYK8
Splice isoforms : SwissVarQ8IYK8
PhosPhoSitePlusQ8IYK8
Domaine pattern : Prosite (Expaxy)RAS (PS51421)   
Domains : Interpro (EBI)P-loop_NTPase    Sigma_54_int_dom_ATP-bd_1    Small_GTPase    Small_GTPase_Ras   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Conserved Domain (NCBI)REM2
DMDM Disease mutations161253
Blocks (Seattle)REM2
PDB (SRS)3CBQ   
PDB (PDBSum)3CBQ   
PDB (IMB)3CBQ   
PDB (RSDB)3CBQ   
Structural Biology KnowledgeBase3CBQ   
SCOP (Structural Classification of Proteins)3CBQ   
CATH (Classification of proteins structures)3CBQ   
SuperfamilyQ8IYK8
Human Protein Atlas [tissue]ENSG00000139890-REM2 [tissue]
Peptide AtlasQ8IYK8
HPRD08248
IPIIPI00793200   IPI00922713   
Protein Interaction databases
DIP (DOE-UCLA)Q8IYK8
IntAct (EBI)Q8IYK8
FunCoupENSG00000139890
BioGRIDREM2
STRING (EMBL)REM2
ZODIACREM2
Ontologies - Pathways
QuickGOQ8IYK8
Ontology : AmiGOGTPase activity  GTP binding  plasma membrane  signal transduction  
Ontology : EGO-EBIGTPase activity  GTP binding  plasma membrane  signal transduction  
NDEx NetworkREM2
Atlas of Cancer Signalling NetworkREM2
Wikipedia pathwaysREM2
Orthology - Evolution
OrthoDB161253
GeneTree (enSembl)ENSG00000139890
Phylogenetic Trees/Animal Genes : TreeFamREM2
HOVERGENQ8IYK8
HOGENOMQ8IYK8
Homologs : HomoloGeneREM2
Homology/Alignments : Family Browser (UCSC)REM2
Gene fusions - Rearrangements
Tumor Fusion PortalREM2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerREM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)REM2
dbVarREM2
ClinVarREM2
1000_GenomesREM2 
Exome Variant ServerREM2
ExAC (Exome Aggregation Consortium)ENSG00000139890
GNOMAD BrowserENSG00000139890
Genetic variants : HAPMAP161253
Genomic Variants (DGV)REM2 [DGVbeta]
DECIPHERREM2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisREM2 
Mutations
ICGC Data PortalREM2 
TCGA Data PortalREM2 
Broad Tumor PortalREM2
OASIS PortalREM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICREM2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDREM2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch REM2
DgiDB (Drug Gene Interaction Database)REM2
DoCM (Curated mutations)REM2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)REM2 (select a term)
intoGenREM2
Cancer3DREM2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616955   
Orphanet
DisGeNETREM2
MedgenREM2
Genetic Testing Registry REM2
NextProtQ8IYK8 [Medical]
TSGene161253
GENETestsREM2
Target ValidationREM2
Huge Navigator REM2 [HugePedia]
snp3D : Map Gene to Disease161253
BioCentury BCIQREM2
ClinGenREM2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD161253
Chemical/Pharm GKB GenePA134916581
Clinical trialREM2
Miscellaneous
canSAR (ICR)REM2 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineREM2
EVEXREM2
GoPubMedREM2
iHOPREM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Nov 21 14:32:07 CET 2017

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