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REN (renin)

Identity

Other namesHNFJ2
HGNC (Hugo) REN
LocusID (NCBI) 5972
Location 1q32.1
Location_base_pair Starts at 204123944 and ends at 204135465 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)REN   9958
Cards
Entrez_Gene (NCBI)REN  5972  renin
GeneCards (Weizmann)REN
Ensembl (Hinxton)ENSG00000143839 [Gene_View]  chr1:204123944-204135465 [Contig_View]  REN [Vega]
ICGC DataPortalENSG00000143839
AceView (NCBI)REN
Genatlas (Paris)REN
WikiGenes5972
SOURCE (Princeton)NM_000537
Genomic and cartography
GoldenPath (UCSC)REN  -  1q32.1   chr1:204123944-204135465 -  1q32.1   [Description]    (hg19-Feb_2009)
EnsemblREN - 1q32.1 [CytoView]
Mapping of homologs : NCBIREN [Mapview]
OMIM179820   267430   613092   
Gene and transcription
Genbank (Entrez)AF117822 BC033474 BC047752 BP321283 CR536498
RefSeq transcript (Entrez)NM_000537
RefSeq genomic (Entrez)AC_000133 NC_000001 NC_018912 NG_012122 NT_004487 NW_001838533 NW_004929293
Consensus coding sequences : CCDS (NCBI)REN
Cluster EST : UnigeneHs.3210 [ NCBI ]
CGAP (NCI)Hs.3210
Alternative Splicing : Fast-db (Paris)GSHG0002874
Alternative Splicing GalleryENSG00000143839
Gene ExpressionREN [ NCBI-GEO ]     REN [ SEEK ]   REN [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP00797 (Uniprot)
NextProtP00797  [Medical]
With graphics : InterProP00797
Splice isoforms : SwissVarP00797 (Swissvar)
Catalytic activity : Enzyme3.4.23.15 [ Enzyme-Expasy ]   3.4.23.153.4.23.15 [ IntEnz-EBI ]   3.4.23.15 [ BRENDA ]   3.4.23.15 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)ASP_PROTEASE (PS00141)   
Domains : Interpro (EBI)Aspartic_peptidase    Aspartic_peptidase_AS    Aspartic_peptidase_N    Peptidase_aspartic_dom   
Related proteins : CluSTrP00797
Domain families : Pfam (Sanger)A1_Propeptide (PF07966)    Asp (PF00026)   
Domain families : Pfam (NCBI)pfam07966    pfam00026   
DMDM Disease mutations5972
Blocks (Seattle)P00797
PDB (SRS)1BBS    1BIL    1BIM    1HRN    1RNE    2BKS    2BKT    2FS4    2G1N    2G1O    2G1R    2G1S    2G1Y    2G20    2G21    2G22    2G24    2G26    2G27    2I4Q    2IKO    2IKU    2IL2    2REN    2V0Z    2V10    2V11    2V12    2V13    2V16    2X0B    3D91    3G6Z    3G70    3G72    3GW5    3K1W    3KM4    3O9L    3OAD    3OAG    3OOT    3OQF    3OQK    3OWN    3Q3T    3Q4B    3Q5H    3SFC    3VCM    3VSW    3VSX    3VUC    3VYD    3VYE    3VYF    4AMT    4GJ5    4GJ6    4GJ7    4GJ8    4GJ9    4GJA    4GJB    4GJC    4GJD   
PDB (PDBSum)1BBS    1BIL    1BIM    1HRN    1RNE    2BKS    2BKT    2FS4    2G1N    2G1O    2G1R    2G1S    2G1Y    2G20    2G21    2G22    2G24    2G26    2G27    2I4Q    2IKO    2IKU    2IL2    2REN    2V0Z    2V10    2V11    2V12    2V13    2V16    2X0B    3D91    3G6Z    3G70    3G72    3GW5    3K1W    3KM4    3O9L    3OAD    3OAG    3OOT    3OQF    3OQK    3OWN    3Q3T    3Q4B    3Q5H    3SFC    3VCM    3VSW    3VSX    3VUC    3VYD    3VYE    3VYF    4AMT    4GJ5    4GJ6    4GJ7    4GJ8    4GJ9    4GJA    4GJB    4GJC    4GJD   
PDB (IMB)1BBS    1BIL    1BIM    1HRN    1RNE    2BKS    2BKT    2FS4    2G1N    2G1O    2G1R    2G1S    2G1Y    2G20    2G21    2G22    2G24    2G26    2G27    2I4Q    2IKO    2IKU    2IL2    2REN    2V0Z    2V10    2V11    2V12    2V13    2V16    2X0B    3D91    3G6Z    3G70    3G72    3GW5    3K1W    3KM4    3O9L    3OAD    3OAG    3OOT    3OQF    3OQK    3OWN    3Q3T    3Q4B    3Q5H    3SFC    3VCM    3VSW    3VSX    3VUC    3VYD    3VYE    3VYF    4AMT    4GJ5    4GJ6    4GJ7    4GJ8    4GJ9    4GJA    4GJB    4GJC    4GJD   
PDB (RSDB)1BBS    1BIL    1BIM    1HRN    1RNE    2BKS    2BKT    2FS4    2G1N    2G1O    2G1R    2G1S    2G1Y    2G20    2G21    2G22    2G24    2G26    2G27    2I4Q    2IKO    2IKU    2IL2    2REN    2V0Z    2V10    2V11    2V12    2V13    2V16    2X0B    3D91    3G6Z    3G70    3G72    3GW5    3K1W    3KM4    3O9L    3OAD    3OAG    3OOT    3OQF    3OQK    3OWN    3Q3T    3Q4B    3Q5H    3SFC    3VCM    3VSW    3VSX    3VUC    3VYD    3VYE    3VYF    4AMT    4GJ5    4GJ6    4GJ7    4GJ8    4GJ9    4GJA    4GJB    4GJC    4GJD   
Human Protein AtlasENSG00000143839
Peptide AtlasP00797
HPRD01564
IPIIPI00019644   IPI00552207   IPI01012588   
Protein Interaction databases
DIP (DOE-UCLA)P00797
IntAct (EBI)P00797
FunCoupENSG00000143839
BioGRIDREN
InParanoidP00797
Interologous Interaction database P00797
IntegromeDBREN
STRING (EMBL)REN
Ontologies - Pathways
Ontology : AmiGOkidney development  mesonephros development  angiotensin maturation  angiotensin maturation  renin-angiotensin regulation of aldosterone production  aspartic-type endopeptidase activity  aspartic-type endopeptidase activity  receptor binding  insulin-like growth factor receptor binding  extracellular region  extracellular space  intracellular  plasma membrane  proteolysis  regulation of blood pressure  peptidase activity  male gonad development  hormone-mediated signaling pathway  response to lipopolysaccharide  cellular response to drug  drinking behavior  regulation of MAPK cascade  cellular protein metabolic process  cell maturation  beta-amyloid metabolic process  response to cAMP  response to cGMP  
Ontology : EGO-EBIkidney development  mesonephros development  angiotensin maturation  angiotensin maturation  renin-angiotensin regulation of aldosterone production  aspartic-type endopeptidase activity  aspartic-type endopeptidase activity  receptor binding  insulin-like growth factor receptor binding  extracellular region  extracellular space  intracellular  plasma membrane  proteolysis  regulation of blood pressure  peptidase activity  male gonad development  hormone-mediated signaling pathway  response to lipopolysaccharide  cellular response to drug  drinking behavior  regulation of MAPK cascade  cellular protein metabolic process  cell maturation  beta-amyloid metabolic process  response to cAMP  response to cGMP  
Pathways : BIOCARTAAngiotensin-converting enzyme 2 regulates heart function [Genes]   
Pathways : KEGGRenin-angiotensin system   
Protein Interaction DatabaseREN
Wikipedia pathwaysREN
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)REN
SNP (GeneSNP Utah)REN
SNP : HGBaseREN
Genetic variants : HAPMAPREN
1000_GenomesREN 
ICGC programENSG00000143839 
CONAN: Copy Number AnalysisREN 
Somatic Mutations in Cancer : COSMICREN 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Mutations and Diseases : HGMDREN
OMIM179820    267430    613092   
MedgenREN
GENETestsREN
Disease Genetic AssociationREN
Huge Navigator REN [HugePedia]  REN [HugeCancerGEM]
Genomic VariantsREN  REN [DGVbeta]
Exome VariantREN
dbVarREN
ClinVarREN
snp3D : Map Gene to Disease5972
General knowledge
Homologs : HomoloGeneREN
Homology/Alignments : Family Browser (UCSC)REN
Phylogenetic Trees/Animal Genes : TreeFamREN
Chemical/Protein Interactions : CTD5972
Chemical/Pharm GKB GenePA297
Clinical trialREN
Cancer Resource (Charite)ENSG00000143839
Other databases
Probes
Litterature
PubMed201 Pubmed reference(s) in Entrez
CoreMineREN
iHOPREN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 13 13:13:00 CEST 2014

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