RENBP (renin binding protein)

2014-11-01  

Identity

HGNC
LOCATION
Xq28
LOCUSID
ALIAS
RBP,RNBP
FUSION GENES

Other Information

Locus ID:

NCBI: 5973
MIM: 312420
HGNC: 9959
Ensembl: ENSG00000102032

Variants:

dbSNP: 5973
ClinVar: 5973
TCGA: ENSG00000102032
COSMIC: RENBP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102032ENST00000369997A6NKZ2
ENSG00000102032ENST00000393700P51606
ENSG00000102032ENST00000423624F8WE83
ENSG00000102032ENST00000442361H7C1A7
ENSG00000102032ENST00000451114H7C317
ENSG00000102032ENST00000457282H7C2G7

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
Amino sugar and nucleotide sugar metabolismKEGGko00520
Amino sugar and nucleotide sugar metabolismKEGGhsa00520
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent proteinREACTOMER-HSA-446193
Synthesis of substrates in N-glycan biosythesisREACTOMER-HSA-446219
Synthesis of UDP-N-acetyl-glucosamineREACTOMER-HSA-446210

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
124993622003GlcNAc 2-epimerase can serve a catabolic role in sialic acid metabolism.25
204862822010Genetic variants in the renin-angiotensin-aldosterone system and salt sensitivity of blood pressure.25
240438782014Common variants on Xq28 conferring risk of schizophrenia in Han Chinese.16
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
124461922002Analysis of several hundred genetic polymorphisms may improve assessment of the individual genetic burden for coronary artery disease.7
119269992002Identification of a domain conferring nucleotide binding to the N-acetyl-d-glucosamine 2-epimerase (Renin binding protein).4
123949502002Angiotensin converting enzyme DD genotype is associated with hypertensive crisis.4
126128742003Selective activation of N-acyl-D-glucosamine 2-epimerase expression in failing human heart ventricular myocytes.0
239692522013Association of renin binding protein (RnBP) gene polymorphisms with essential hypertension in the Hani minority of southwestern China.0

Citation

Dessen P

RENBP (renin binding protein)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72578/renbp