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REXO2 (RNA exonuclease 2)

Identity

Alias_namesREX2
Alias_symbol (synonym)DKFZP566E144
SFN
CGI-114
Other aliasRFN
HGNC (Hugo) REXO2
LocusID (NCBI) 25996
Atlas_Id 40321
Location 11q23.2  [Link to chromosome band 11q23]
Location_base_pair Starts at 114439386 and ends at 114450278 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
REXO2 (11q23.2) / MPHOSPH8 (13q12.11)REXO2 (11q23.2) / SARM1 (17q11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)REXO2   17851
Cards
Entrez_Gene (NCBI)REXO2  25996  RNA exonuclease 2
AliasesCGI-114; REX2; RFN; SFN
GeneCards (Weizmann)REXO2
Ensembl hg19 (Hinxton)ENSG00000076043 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000076043 [Gene_View]  chr11:114439386-114450278 [Contig_View]  REXO2 [Vega]
ICGC DataPortalENSG00000076043
TCGA cBioPortalREXO2
AceView (NCBI)REXO2
Genatlas (Paris)REXO2
WikiGenes25996
SOURCE (Princeton)REXO2
Genetics Home Reference (NIH)REXO2
Genomic and cartography
GoldenPath hg38 (UCSC)REXO2  -     chr11:114439386-114450278 +  11q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)REXO2  -     11q23.2   [Description]    (hg19-Feb_2009)
EnsemblREXO2 - 11q23.2 [CytoView hg19]  REXO2 - 11q23.2 [CytoView hg38]
Mapping of homologs : NCBIREXO2 [Mapview hg19]  REXO2 [Mapview hg38]
OMIM607149   
Gene and transcription
Genbank (Entrez)AF151872 AI249345 AK023498 AK223200 AK312042
RefSeq transcript (Entrez)NM_015523
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)REXO2
Cluster EST : UnigeneHs.714231 [ NCBI ]
CGAP (NCI)Hs.714231
Alternative Splicing GalleryENSG00000076043
Gene ExpressionREXO2 [ NCBI-GEO ]   REXO2 [ EBI - ARRAY_EXPRESS ]   REXO2 [ SEEK ]   REXO2 [ MEM ]
Gene Expression Viewer (FireBrowse)REXO2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25996
GTEX Portal (Tissue expression)REXO2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y3B8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y3B8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y3B8
Splice isoforms : SwissVarQ9Y3B8
Catalytic activity : Enzyme3.1.-.- [ Enzyme-Expasy ]   3.1.-.-3.1.-.- [ IntEnz-EBI ]   3.1.-.- [ BRENDA ]   3.1.-.- [ KEGG ]   
PhosPhoSitePlusQ9Y3B8
Domains : Interpro (EBI)Exonuclease_RNaseT/DNA_pol3    Oligoribonuclease    RNaseH-like_dom   
Domain families : Pfam (Sanger)RNase_T (PF00929)   
Domain families : Pfam (NCBI)pfam00929   
Domain families : Smart (EMBL)EXOIII (SM00479)  
Conserved Domain (NCBI)REXO2
DMDM Disease mutations25996
Blocks (Seattle)REXO2
SuperfamilyQ9Y3B8
Human Protein AtlasENSG00000076043
Peptide AtlasQ9Y3B8
HPRD06192
IPIIPI00032830   IPI00217330   IPI01012443   IPI01009259   IPI01009750   IPI01010096   IPI01010568   IPI01014414   IPI01014883   IPI01012701   IPI01011224   IPI01011749   IPI01012069   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y3B8
IntAct (EBI)Q9Y3B8
FunCoupENSG00000076043
BioGRIDREXO2
STRING (EMBL)REXO2
ZODIACREXO2
Ontologies - Pathways
QuickGOQ9Y3B8
Ontology : AmiGOnucleic acid binding  nucleus  nucleolus  mitochondrion  mitochondrial intermembrane space  mitochondrial matrix  focal adhesion  nucleobase-containing compound metabolic process  3'-5' exonuclease activity  nucleotide metabolic process  nucleic acid phosphodiester bond hydrolysis  
Ontology : EGO-EBInucleic acid binding  nucleus  nucleolus  mitochondrion  mitochondrial intermembrane space  mitochondrial matrix  focal adhesion  nucleobase-containing compound metabolic process  3'-5' exonuclease activity  nucleotide metabolic process  nucleic acid phosphodiester bond hydrolysis  
Pathways : KEGGRibosome biogenesis in eukaryotes   
NDEx NetworkREXO2
Atlas of Cancer Signalling NetworkREXO2
Wikipedia pathwaysREXO2
Orthology - Evolution
OrthoDB25996
GeneTree (enSembl)ENSG00000076043
Phylogenetic Trees/Animal Genes : TreeFamREXO2
HOVERGENQ9Y3B8
HOGENOMQ9Y3B8
Homologs : HomoloGeneREXO2
Homology/Alignments : Family Browser (UCSC)REXO2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerREXO2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)REXO2
dbVarREXO2
ClinVarREXO2
1000_GenomesREXO2 
Exome Variant ServerREXO2
ExAC (Exome Aggregation Consortium)REXO2 (select the gene name)
Genetic variants : HAPMAP25996
Genomic Variants (DGV)REXO2 [DGVbeta]
DECIPHERREXO2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisREXO2 
Mutations
ICGC Data PortalREXO2 
TCGA Data PortalREXO2 
Broad Tumor PortalREXO2
OASIS PortalREXO2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICREXO2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDREXO2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch REXO2
DgiDB (Drug Gene Interaction Database)REXO2
DoCM (Curated mutations)REXO2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)REXO2 (select a term)
intoGenREXO2
Cancer3DREXO2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607149   
Orphanet
MedgenREXO2
Genetic Testing Registry REXO2
NextProtQ9Y3B8 [Medical]
TSGene25996
GENETestsREXO2
Huge Navigator REXO2 [HugePedia]
snp3D : Map Gene to Disease25996
BioCentury BCIQREXO2
ClinGenREXO2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD25996
Chemical/Pharm GKB GenePA142671085
Clinical trialREXO2
Miscellaneous
canSAR (ICR)REXO2 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineREXO2
EVEXREXO2
GoPubMedREXO2
iHOPREXO2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:34:44 CEST 2017

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