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REXO4 (REX4 homolog, 3'-5' exonuclease)

Identity

Alias_namesXPMC2H
Xenopus prevents mitotic catatrophe 2 homolog
XPMC2 prevents mitotic catastrophe 2 homolog (Xenopus laevis)
REX4, RNA exonuclease 4 homolog (S. cerevisiae)
Alias_symbol (synonym)hPMC2
Other aliasREX4
XPMC2
HGNC (Hugo) REXO4
LocusID (NCBI) 57109
Atlas_Id 52560
Location 9q34.2  [Link to chromosome band 9q34]
Location_base_pair Starts at 133406058 and ends at 133418096 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)REXO4   12820
Cards
Entrez_Gene (NCBI)REXO4  57109  REX4 homolog, 3'-5' exonuclease
AliasesREX4; XPMC2; XPMC2H
GeneCards (Weizmann)REXO4
Ensembl hg19 (Hinxton)ENSG00000148300 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148300 [Gene_View]  chr9:133406058-133418096 [Contig_View]  REXO4 [Vega]
ICGC DataPortalENSG00000148300
TCGA cBioPortalREXO4
AceView (NCBI)REXO4
Genatlas (Paris)REXO4
WikiGenes57109
SOURCE (Princeton)REXO4
Genetics Home Reference (NIH)REXO4
Genomic and cartography
GoldenPath hg38 (UCSC)REXO4  -     chr9:133406058-133418096 -  9q34.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)REXO4  -     9q34.2   [Description]    (hg19-Feb_2009)
EnsemblREXO4 - 9q34.2 [CytoView hg19]  REXO4 - 9q34.2 [CytoView hg38]
Mapping of homologs : NCBIREXO4 [Mapview hg19]  REXO4 [Mapview hg38]
OMIM602930   
Gene and transcription
Genbank (Entrez)AF273304 AF295774 AK000247 AK025493 AK295982
RefSeq transcript (Entrez)NM_001279349 NM_001279350 NM_001279351 NM_020385
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)REXO4
Cluster EST : UnigeneHs.438409 [ NCBI ]
CGAP (NCI)Hs.438409
Alternative Splicing GalleryENSG00000148300
Gene ExpressionREXO4 [ NCBI-GEO ]   REXO4 [ EBI - ARRAY_EXPRESS ]   REXO4 [ SEEK ]   REXO4 [ MEM ]
Gene Expression Viewer (FireBrowse)REXO4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57109
GTEX Portal (Tissue expression)REXO4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9GZR2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9GZR2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9GZR2
Splice isoforms : SwissVarQ9GZR2
Catalytic activity : Enzyme3.1.-.- [ Enzyme-Expasy ]   3.1.-.-3.1.-.- [ IntEnz-EBI ]   3.1.-.- [ BRENDA ]   3.1.-.- [ KEGG ]   
PhosPhoSitePlusQ9GZR2
Domains : Interpro (EBI)Exonuclease_RNaseT/DNA_pol3    RNaseH-like_dom   
Domain families : Pfam (Sanger)RNase_T (PF00929)   
Domain families : Pfam (NCBI)pfam00929   
Domain families : Smart (EMBL)EXOIII (SM00479)  
Conserved Domain (NCBI)REXO4
DMDM Disease mutations57109
Blocks (Seattle)REXO4
SuperfamilyQ9GZR2
Human Protein AtlasENSG00000148300
Peptide AtlasQ9GZR2
HPRD04239
IPIIPI00010653   IPI00513877   IPI00642137   IPI00643219   
Protein Interaction databases
DIP (DOE-UCLA)Q9GZR2
IntAct (EBI)Q9GZR2
FunCoupENSG00000148300
BioGRIDREXO4
STRING (EMBL)REXO4
ZODIACREXO4
Ontologies - Pathways
QuickGOQ9GZR2
Ontology : AmiGOtranscription factor activity, sequence-specific DNA binding  RNA binding  exonuclease activity  nucleus  nucleus  nucleolus  regulation of transcription, DNA-templated  nuclear speck  nucleic acid phosphodiester bond hydrolysis  
Ontology : EGO-EBItranscription factor activity, sequence-specific DNA binding  RNA binding  exonuclease activity  nucleus  nucleus  nucleolus  regulation of transcription, DNA-templated  nuclear speck  nucleic acid phosphodiester bond hydrolysis  
NDEx NetworkREXO4
Atlas of Cancer Signalling NetworkREXO4
Wikipedia pathwaysREXO4
Orthology - Evolution
OrthoDB57109
GeneTree (enSembl)ENSG00000148300
Phylogenetic Trees/Animal Genes : TreeFamREXO4
HOVERGENQ9GZR2
HOGENOMQ9GZR2
Homologs : HomoloGeneREXO4
Homology/Alignments : Family Browser (UCSC)REXO4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerREXO4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)REXO4
dbVarREXO4
ClinVarREXO4
1000_GenomesREXO4 
Exome Variant ServerREXO4
ExAC (Exome Aggregation Consortium)REXO4 (select the gene name)
Genetic variants : HAPMAP57109
Genomic Variants (DGV)REXO4 [DGVbeta]
DECIPHERREXO4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisREXO4 
Mutations
ICGC Data PortalREXO4 
TCGA Data PortalREXO4 
Broad Tumor PortalREXO4
OASIS PortalREXO4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICREXO4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDREXO4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch REXO4
DgiDB (Drug Gene Interaction Database)REXO4
DoCM (Curated mutations)REXO4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)REXO4 (select a term)
intoGenREXO4
Cancer3DREXO4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602930   
Orphanet
MedgenREXO4
Genetic Testing Registry REXO4
NextProtQ9GZR2 [Medical]
TSGene57109
GENETestsREXO4
Target ValidationREXO4
Huge Navigator REXO4 [HugePedia]
snp3D : Map Gene to Disease57109
BioCentury BCIQREXO4
ClinGenREXO4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57109
Chemical/Pharm GKB GenePA37414
Clinical trialREXO4
Miscellaneous
canSAR (ICR)REXO4 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineREXO4
EVEXREXO4
GoPubMedREXO4
iHOPREXO4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:53:01 CEST 2017

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