| Nomenclature | | HGNC (Hugo) | RFC1 9969 |
| Entrez_Gene (NCBI) | RFC1 5981 replication factor C (activator 1) 1, 145kDa |
| Cards | | GeneCards (Weizmann) | RFC1 |
| Ensembl (Hinxton) | ENSG00000035928 [Gene_View] chr4:39289069-39368001 [Contig_View] RFC1 [Vega] |
| AceView (NCBI) | RFC1 |
| Genatlas (Paris) | RFC1 |
| SOURCE (Stanford) | NM_001204747 NM_002913 |
| Genomic and cartography | | GoldenPath (UCSC) | RFC1 - 4p14 chr4:39289069-39368001 - 4p14 [Description] (hg19-Feb_2009) |
| Ensembl | RFC1 - 4p14 [CytoView] |
| Mapping of homologs : NCBI | RFC1 [Mapview] |
| OMIM | 102579 |
| Gene and transcription |
| Genbank (Entrez) | AF040250 AJ564999 AK291612 BC010387 BC035297 |
| RefSeq transcript (SRS) | NM_001204747 NM_002913 |
| RefSeq transcript (Entrez) | NM_001204747 NM_002913 |
| RefSeq genomic (SRS) | AC_000136 NC_000004 NC_018915 NT_016297 NW_001838902 NW_004078018 |
| RefSeq genomic (Entrez) | AC_000136 NC_000004 NC_018915 NT_016297 NW_001838902 NW_004078018 |
| Consensus coding sequences : CCDS (NCBI) | RFC1 |
| Cluster EST : Unigene | Hs.507475 [ SRS ] Hs.507475 [ NCBI ] |
| CGAP (NCI) | Hs.507475 |
| Alternative Splicing : Fast-db (Paris) | GSHG0023204 |
| Alternative Splicing Gallery | ENSG00000035928 |
| Gene Expression | RFC1 [ NCBI-GEO ] RFC1 [ EBI - ARRAY_EXPRESS ] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P35251 (SRS) P35251 (Uniprot) |
| NextProt | P35251 |
| With graphics : InterPro | P35251 |
| Splice isoforms : SwissVar | P35251(Swissvar) |
| Domaine pattern : Prosite (SRS) | BRCT (PS50172) |
| Domaine pattern : Prosite (Expaxy) | BRCT (PS50172) |
| Domains : Interpro (SRS) | AAA+_ATPase ATPase_AAA_core BRCT_dom DNA_pol3_clamp-load_cplx_C DNA_replication_fac_C_lsu DNA_replication_fac_RFC1_C |
| Domains : Interpro (EBI) | AAA+_ATPase ATPase_AAA_core BRCT_dom DNA_pol3_clamp-load_cplx_C DNA_replication_fac_C_lsu DNA_replication_fac_RFC1_C |
| Related proteins : CluSTr | P35251 |
| Domain families : Pfam (SRS) | AAA (PF00004) BRCT (PF00533) RFC1 (PF08519) |
| Domain families : Pfam (Sanger) | AAA (PF00004) BRCT (PF00533) RFC1 (PF08519) |
| Domain families : Pfam (NCBI) | pfam00004 pfam00533 pfam08519 |
| Domain families : Smart (EMBL) | AAA (SM00382) BRCT (SM00292) |
| DMDM | 5981 |
| Blocks (Seattle) | P35251 |
| PDB (SRS) | 2EBU 2K6G 2K7F |
| PDB (PDBSum) | 2EBU 2K6G 2K7F |
| PDB (IMB) | 2EBU 2K6G 2K7F |
| PDB (RSDB) | 2EBU 2K6G 2K7F |
| Human Protein Atlas | ENSG00000035928 |
| HPRD | 00024 |
| IPI | IPI00375358 IPI00375359 IPI00382816 IPI00965714 IPI00964047 IPI00966063 IPI00965979 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P35251 |
| IntAct (EBI) | P35251 |
| FunCoup | ENSG00000035928 |
| REACTOME | RFC1 |
| Protein Interaction Database | 5981 |
| BioGRID | RFC1 |
| InParanoid | P35251 |
| Interologous Interaction database | P35251 |
| IntegromeDB | RFC1 |
| Polymorphism : SNP, mutations, diseases | | SNP Single Nucleotide Polymorphism (NCBI) | RFC1 |
| SNP (GeneSNP Utah) | RFC1 |
| SNP : HGBase | RFC1 |
| Genetic variants : HAPMAP | RFC1 |
| Somatic Mutations in Cancer : COSMIC | RFC1 |
| CONAN: Copy Number Analysis | RFC1 |
| Mutations and Diseases : HGMD | RFC1 |
| OMIM | 102579 |
| GENETests | 102579 |
| Disease Genetic Association | RFC1 |
| Huge Navigator |
RFC1 [HugePedia] RFC1 [HugeCancerGEM] |
| Genomic Variants | RFC1 RFC1 [DGVbeta] |
| ClinVar | RFC1 |
| snp3D : Map Gene to Disease | 5981 |
| General knowledge |
|---|
| Homologs : HomoloGene | RFC1 |
| Homology/Alignments : Family Browser (UCSC) | RFC1 |
| Phylogenetic Trees/Animal Genes : TreeFam | RFC1 |
| Chemical/Protein Interactions : CTD | 5981 |
| Chemical/Pharm GKB Gene | PA34338 |
| Clinical trial | RFC1 |
| Cancer Resource (Charite) | ENSG00000035928 |
| Ontology : AmiGO | S phase of mitotic cell cycle mitotic cell cycle telomere maintenance via recombination telomere maintenance DNA clamp loader activity protein binding ATP binding nucleoplasm DNA replication factor C complex DNA-dependent DNA replication DNA strand elongation involved in DNA replication DNA repair transcription-coupled nucleotide-excision repair nucleotide-excision repair nucleotide-excision repair, DNA gap filling transcription, DNA-dependent regulation of transcription, DNA-dependent telomere maintenance via telomerase enzyme activator activity telomere maintenance via semi-conservative replication positive regulation of catalytic activity |
| Ontology : EGO-EBI | S phase of mitotic cell cycle mitotic cell cycle telomere maintenance via recombination telomere maintenance DNA clamp loader activity protein binding ATP binding nucleoplasm DNA replication factor C complex DNA-dependent DNA replication DNA strand elongation involved in DNA replication DNA repair transcription-coupled nucleotide-excision repair nucleotide-excision repair nucleotide-excision repair, DNA gap filling transcription, DNA-dependent regulation of transcription, DNA-dependent telomere maintenance via telomerase enzyme activator activity telomere maintenance via semi-conservative replication positive regulation of catalytic activity |
| Pathways : BIOCARTA | ALK in cardiac myocytes [Genes] |
| Other databases |
| Probes |
|---|
| Litterature | | PubMed | 166 Pubmed reference(s) in Entrez |
| PubGene | RFC1 |
| iHOP | RFC1 |
