Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

RFPL1 (ret finger protein like 1)

Identity

Alias (NCBI)RNF78
HGNC (Hugo) RFPL1
HGNC Alias symbRNF78
LocusID (NCBI) 5988
Atlas_Id 57788
Location 22q12.2  [Link to chromosome band 22q12]
Location_base_pair Starts at 29438583 and ends at 29442455 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)RFPL1   9977
Cards
Entrez_Gene (NCBI)RFPL1    ret finger protein like 1
AliasesRNF78
GeneCards (Weizmann)RFPL1
Ensembl hg19 (Hinxton)ENSG00000128250 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000128250 [Gene_View]  ENSG00000128250 [Sequence]  chr22:29438583-29442455 [Contig_View]  RFPL1 [Vega]
ICGC DataPortalENSG00000128250
TCGA cBioPortalRFPL1
AceView (NCBI)RFPL1
Genatlas (Paris)RFPL1
SOURCE (Princeton)RFPL1
Genetics Home Reference (NIH)RFPL1
Genomic and cartography
GoldenPath hg38 (UCSC)RFPL1  -     chr22:29438583-29442455 +  22q12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RFPL1  -     22q12.2   [Description]    (hg19-Feb_2009)
GoldenPathRFPL1 - 22q12.2 [CytoView hg19]  RFPL1 - 22q12.2 [CytoView hg38]
ImmunoBaseENSG00000128250
genome Data Viewer NCBIRFPL1 [Mapview hg19]  
OMIM605968   
Gene and transcription
Genbank (Entrez)AJ010228 AJ010229 BC104768 CR456562
RefSeq transcript (Entrez)NM_021026
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RFPL1
Alternative Splicing GalleryENSG00000128250
Gene ExpressionRFPL1 [ NCBI-GEO ]   RFPL1 [ EBI - ARRAY_EXPRESS ]   RFPL1 [ SEEK ]   RFPL1 [ MEM ]
Gene Expression Viewer (FireBrowse)RFPL1 [ Firebrowse - Broad ]
GenevisibleExpression of RFPL1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5988
GTEX Portal (Tissue expression)RFPL1
Human Protein AtlasENSG00000128250-RFPL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75677   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75677  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75677
Splice isoforms : SwissVarO75677
PhosPhoSitePlusO75677
Domaine pattern : Prosite (Expaxy)B302_SPRY (PS50188)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)B30.2/SPRY    Butyrophylin_SPRY    ConA-like_dom_sf    PRY    RDM_domain_RFPL    RFPL    SPRY/PRY_RFPL    SPRY_dom    Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)PRY (PF13765)    RDM (PF11002)    SPRY (PF00622)   
Domain families : Pfam (NCBI)pfam13765    pfam11002    pfam00622   
Domain families : Smart (EMBL)PRY (SM00589)  SPRY (SM00449)  
Conserved Domain (NCBI)RFPL1
Blocks (Seattle)RFPL1
SuperfamilyO75677
Human Protein Atlas [tissue]ENSG00000128250-RFPL1 [tissue]
Peptide AtlasO75677
IPIIPI00465224   
Protein Interaction databases
DIP (DOE-UCLA)O75677
IntAct (EBI)O75677
BioGRIDRFPL1
STRING (EMBL)RFPL1
ZODIACRFPL1
Ontologies - Pathways
QuickGOO75677
Ontology : AmiGOchromatin  ubiquitin-protein transferase activity  nucleoplasm  cytoplasm  cell cycle  negative regulation of cell proliferation  negative regulation of G2/M transition of mitotic cell cycle  protein ubiquitination  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  positive regulation of apoptotic process  positive regulation of transcription, DNA-templated  negative regulation of mitotic cell cycle  metal ion binding  negative regulation of cell division  positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis  
Ontology : EGO-EBIchromatin  ubiquitin-protein transferase activity  nucleoplasm  cytoplasm  cell cycle  negative regulation of cell proliferation  negative regulation of G2/M transition of mitotic cell cycle  protein ubiquitination  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  positive regulation of apoptotic process  positive regulation of transcription, DNA-templated  negative regulation of mitotic cell cycle  metal ion binding  negative regulation of cell division  positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis  
NDEx NetworkRFPL1
Atlas of Cancer Signalling NetworkRFPL1
Wikipedia pathwaysRFPL1
Orthology - Evolution
OrthoDB5988
GeneTree (enSembl)ENSG00000128250
Phylogenetic Trees/Animal Genes : TreeFamRFPL1
HOGENOMO75677
Homologs : HomoloGeneRFPL1
Homology/Alignments : Family Browser (UCSC)RFPL1
Gene fusions - Rearrangements
Fusion : QuiverRFPL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRFPL1 [hg38]
dbVarRFPL1
ClinVarRFPL1
MonarchRFPL1
1000_GenomesRFPL1 
Exome Variant ServerRFPL1
GNOMAD BrowserENSG00000128250
Varsome BrowserRFPL1
Genomic Variants (DGV)RFPL1 [DGVbeta]
DECIPHERRFPL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRFPL1 
Mutations
ICGC Data PortalRFPL1 
TCGA Data PortalRFPL1 
Broad Tumor PortalRFPL1
OASIS PortalRFPL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRFPL1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRFPL1
Mutations and Diseases : HGMDRFPL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RFPL1
DgiDB (Drug Gene Interaction Database)RFPL1
DoCM (Curated mutations)RFPL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RFPL1 (select a term)
intoGenRFPL1
Cancer3DRFPL1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605968   
Orphanet
DisGeNETRFPL1
MedgenRFPL1
Genetic Testing Registry RFPL1
NextProtO75677 [Medical]
GENETestsRFPL1
Target ValidationRFPL1
Huge Navigator RFPL1 [HugePedia]
ClinGenRFPL1
Clinical trials, drugs, therapy
MyCancerGenomeRFPL1
Protein Interactions : CTD
Pharm GKB GenePA34346
PharosO75677
Clinical trialRFPL1
Miscellaneous
canSAR (ICR)RFPL1 (select the gene name)
HarmonizomeRFPL1
DataMed IndexRFPL1
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRFPL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jan 1 18:34:53 CET 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.