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RFTN1 (raftlin, lipid raft linker 1)

Identity

Alias_symbol (synonym)MIG2
KIAA0084
FLJ23866
Raftlin
Other aliasPIB10
PIG9
RAFTLIN
HGNC (Hugo) RFTN1
LocusID (NCBI) 23180
Atlas_Id 53450
Location 3p24.3  [Link to chromosome band 3p24]
Location_base_pair Starts at 16315845 and ends at 16513715 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ANKRD28 (3p25.1) / RFTN1 (3p25.1)RFTN1 (3p25.1) / DAZL (3p24.3)RFTN1 (3p25.1) / MAPK9 (5q35.3)
RFTN1 (3p25.1) / PVT1 (8q24.21)RFTN1 (3p25.1) / RFTN1 (3p25.1)ANKRD28 3p25.1 / RFTN1 3p25.1
RFTN1 3p25.1 / DAZL 3p24.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RFTN1   30278
Cards
Entrez_Gene (NCBI)RFTN1  23180  raftlin, lipid raft linker 1
AliasesMIG2; PIB10; PIG9; RAFTLIN
GeneCards (Weizmann)RFTN1
Ensembl hg19 (Hinxton)ENSG00000131378 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000131378 [Gene_View]  chr3:16315845-16513715 [Contig_View]  RFTN1 [Vega]
ICGC DataPortalENSG00000131378
TCGA cBioPortalRFTN1
AceView (NCBI)RFTN1
Genatlas (Paris)RFTN1
WikiGenes23180
SOURCE (Princeton)RFTN1
Genetics Home Reference (NIH)RFTN1
Genomic and cartography
GoldenPath hg38 (UCSC)RFTN1  -     chr3:16315845-16513715 -  3p24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RFTN1  -     3p24.3   [Description]    (hg19-Feb_2009)
EnsemblRFTN1 - 3p24.3 [CytoView hg19]  RFTN1 - 3p24.3 [CytoView hg38]
Mapping of homologs : NCBIRFTN1 [Mapview hg19]  RFTN1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK074446 AK301024 AK303846 AK310258 AU138240
RefSeq transcript (Entrez)NM_015150
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RFTN1
Cluster EST : UnigeneHs.98910 [ NCBI ]
CGAP (NCI)Hs.98910
Alternative Splicing GalleryENSG00000131378
Gene ExpressionRFTN1 [ NCBI-GEO ]   RFTN1 [ EBI - ARRAY_EXPRESS ]   RFTN1 [ SEEK ]   RFTN1 [ MEM ]
Gene Expression Viewer (FireBrowse)RFTN1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23180
GTEX Portal (Tissue expression)RFTN1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14699   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14699  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14699
Splice isoforms : SwissVarQ14699
PhosPhoSitePlusQ14699
Domains : Interpro (EBI)Raftlin   
Domain families : Pfam (Sanger)Raftlin (PF15250)   
Domain families : Pfam (NCBI)pfam15250   
Conserved Domain (NCBI)RFTN1
DMDM Disease mutations23180
Blocks (Seattle)RFTN1
SuperfamilyQ14699
Human Protein AtlasENSG00000131378
Peptide AtlasQ14699
HPRD17950
IPIIPI00749454   IPI00643829   IPI00797188   IPI00926693   IPI00926502   IPI00926130   IPI00925899   
Protein Interaction databases
DIP (DOE-UCLA)Q14699
IntAct (EBI)Q14699
FunCoupENSG00000131378
BioGRIDRFTN1
STRING (EMBL)RFTN1
ZODIACRFTN1
Ontologies - Pathways
QuickGOQ14699
Ontology : AmiGOmembrane raft assembly  T cell antigen processing and presentation  double-stranded RNA binding  cytoplasm  endosome  plasma membrane  protein transport into membrane raft  protein transport into membrane raft  interleukin-17 production  dsRNA transport  toll-like receptor 3 signaling pathway  growth  protein complex  response to exogenous dsRNA  membrane raft  T cell receptor signaling pathway  B cell receptor signaling pathway  extracellular exosome  protein localization to membrane raft  
Ontology : EGO-EBImembrane raft assembly  T cell antigen processing and presentation  double-stranded RNA binding  cytoplasm  endosome  plasma membrane  protein transport into membrane raft  protein transport into membrane raft  interleukin-17 production  dsRNA transport  toll-like receptor 3 signaling pathway  growth  protein complex  response to exogenous dsRNA  membrane raft  T cell receptor signaling pathway  B cell receptor signaling pathway  extracellular exosome  protein localization to membrane raft  
NDEx NetworkRFTN1
Atlas of Cancer Signalling NetworkRFTN1
Wikipedia pathwaysRFTN1
Orthology - Evolution
OrthoDB23180
GeneTree (enSembl)ENSG00000131378
Phylogenetic Trees/Animal Genes : TreeFamRFTN1
HOVERGENQ14699
HOGENOMQ14699
Homologs : HomoloGeneRFTN1
Homology/Alignments : Family Browser (UCSC)RFTN1
Gene fusions - Rearrangements
Fusion : MitelmanANKRD28/RFTN1 [3p25.1/3p25.1]  [t(3;3)(p24;p25)]  
Fusion : MitelmanRFTN1/DAZL [3p25.1/3p24.3]  [t(3;3)(p24;p24)]  
Fusion : MitelmanRFTN1/PVT1 [3p25.1/8q24.21]  [t(3;8)(p24;q24)]  
Fusion: TCGAANKRD28 3p25.1 RFTN1 3p25.1 LUSC
Fusion: TCGARFTN1 3p25.1 DAZL 3p24.3 BRCA LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRFTN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RFTN1
dbVarRFTN1
ClinVarRFTN1
1000_GenomesRFTN1 
Exome Variant ServerRFTN1
ExAC (Exome Aggregation Consortium)RFTN1 (select the gene name)
Genetic variants : HAPMAP23180
Genomic Variants (DGV)RFTN1 [DGVbeta]
DECIPHERRFTN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRFTN1 
Mutations
ICGC Data PortalRFTN1 
TCGA Data PortalRFTN1 
Broad Tumor PortalRFTN1
OASIS PortalRFTN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRFTN1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRFTN1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RFTN1
DgiDB (Drug Gene Interaction Database)RFTN1
DoCM (Curated mutations)RFTN1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RFTN1 (select a term)
intoGenRFTN1
Cancer3DRFTN1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenRFTN1
Genetic Testing Registry RFTN1
NextProtQ14699 [Medical]
TSGene23180
GENETestsRFTN1
Huge Navigator RFTN1 [HugePedia]
snp3D : Map Gene to Disease23180
BioCentury BCIQRFTN1
ClinGenRFTN1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23180
Chemical/Pharm GKB GenePA162401206
Clinical trialRFTN1
Miscellaneous
canSAR (ICR)RFTN1 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRFTN1
EVEXRFTN1
GoPubMedRFTN1
iHOPRFTN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:34:47 CEST 2017

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