Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 222546
MIM: 612659
HGNC: 21478
Ensembl: ENSG00000185002
Variants:
dbSNP: 222546
ClinVar: 222546
TCGA: ENSG00000185002
COSMIC: RFX6
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000185002 | ENST00000332958 | Q8HWS3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38064570 | 2024 | RFX6 Maintains Gene Expression and Function of Adult Human Islet α-Cells. | 1 |
| 38587174 | 2024 | RFX6 regulates human intestinal patterning and function upstream of PDX1. | 0 |
| 38064570 | 2024 | RFX6 Maintains Gene Expression and Function of Adult Human Islet α-Cells. | 1 |
| 38587174 | 2024 | RFX6 regulates human intestinal patterning and function upstream of PDX1. | 0 |
| 38093528 | 2023 | RFX6 facilitates aerobic glycolysis-mediated growth and metastasis of hepatocellular carcinoma through targeting PGAM1. | 5 |
| 38093528 | 2023 | RFX6 facilitates aerobic glycolysis-mediated growth and metastasis of hepatocellular carcinoma through targeting PGAM1. | 5 |
| 33721395 | 2021 | A novel RFX6 heterozygous mutation (p.R652X) in maturity-onset diabetes mellitus: A case report. | 2 |
| 33721395 | 2021 | A novel RFX6 heterozygous mutation (p.R652X) in maturity-onset diabetes mellitus: A case report. | 2 |
| 33033118 | 2020 | Mitchell-Riley syndrome iPSCs exhibit reduced pancreatic endoderm differentiation due to a mutation in RFX6. | 6 |
| 33033118 | 2020 | Mitchell-Riley syndrome iPSCs exhibit reduced pancreatic endoderm differentiation due to a mutation in RFX6. | 6 |
| 29026101 | 2017 | Heterozygous RFX6 protein truncating variants are associated with MODY with reduced penetrance. | 55 |
| 29026101 | 2017 | Heterozygous RFX6 protein truncating variants are associated with MODY with reduced penetrance. | 55 |
| 26264437 | 2015 | Biallelic RFX6 mutations can cause childhood as well as neonatal onset diabetes mellitus. | 16 |
| 26537068 | 2015 | Association of THADA, FOXP4, GPRC6A/RFX6 genes and 8q24 risk alleles with prostate cancer in Northern Chinese men. | 5 |
| 26264437 | 2015 | Biallelic RFX6 mutations can cause childhood as well as neonatal onset diabetes mellitus. | 16 |
Citation
Dessen P
RFX6 (regulatory factor X6)
Atlas Genet Cytogenet Oncol Haematol. 2013-01-01
Online version: http://atlasgeneticsoncology.org/gene/53133/rfx6
