Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

RGL1 (ral guanine nucleotide dissociation stimulator like 1)

Identity

Alias_symbol (synonym)RGL
Other alias
HGNC (Hugo) RGL1
LocusID (NCBI) 23179
Atlas_Id 47090
Location 1q25.3  [Link to chromosome band 1q25]
Location_base_pair Starts at 183636047 and ends at 183928551 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BACE2 (21q22.2) / RGL1 (1q25.3)DENND1B (1q31.3) / RGL1 (1q25.3)MAL (2q11.1) / RGL1 (1q25.3)
RGL1 (1q25.3) / HMCN1 (1q25.3)RGL1 (1q25.3) / PSMF1 (20p13)RGL1 (1q25.3) / RTN4 (2p16.1)
VAV3 (1p13.3) / RGL1 (1q25.3)DENND1B 1q31.3 / RGL1 1q25.3RGL1 1q25.3 / HMCN1 1q25.3
VAV3 1p13.3 / RGL1 1q25.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RGL1   30281
Cards
Entrez_Gene (NCBI)RGL1  23179  ral guanine nucleotide dissociation stimulator like 1
AliasesRGL
GeneCards (Weizmann)RGL1
Ensembl hg19 (Hinxton)ENSG00000143344 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000143344 [Gene_View]  chr1:183636047-183928551 [Contig_View]  RGL1 [Vega]
ICGC DataPortalENSG00000143344
TCGA cBioPortalRGL1
AceView (NCBI)RGL1
Genatlas (Paris)RGL1
WikiGenes23179
SOURCE (Princeton)RGL1
Genetics Home Reference (NIH)RGL1
Genomic and cartography
GoldenPath hg38 (UCSC)RGL1  -     chr1:183636047-183928551 +  1q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RGL1  -     1q25.3   [Description]    (hg19-Feb_2009)
EnsemblRGL1 - 1q25.3 [CytoView hg19]  RGL1 - 1q25.3 [CytoView hg38]
Mapping of homologs : NCBIRGL1 [Mapview hg19]  RGL1 [Mapview hg38]
OMIM605667   
Gene and transcription
Genbank (Entrez)AB023176 AF186779 AF186780 AK295179 AK295611
RefSeq transcript (Entrez)NM_001297669 NM_001297670 NM_001297671 NM_001297672 NM_015149
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RGL1
Cluster EST : UnigeneHs.497148 [ NCBI ]
CGAP (NCI)Hs.497148
Alternative Splicing GalleryENSG00000143344
Gene ExpressionRGL1 [ NCBI-GEO ]   RGL1 [ EBI - ARRAY_EXPRESS ]   RGL1 [ SEEK ]   RGL1 [ MEM ]
Gene Expression Viewer (FireBrowse)RGL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23179
GTEX Portal (Tissue expression)RGL1
Human Protein AtlasENSG00000143344-RGL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NZL6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NZL6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NZL6
Splice isoforms : SwissVarQ9NZL6
PhosPhoSitePlusQ9NZL6
Domaine pattern : Prosite (Expaxy)RA (PS50200)    RASGEF (PS00720)    RASGEF_CAT (PS50009)    RASGEF_NTER (PS50212)   
Domains : Interpro (EBI)RA_dom    Ras-like_Gua-exchang_fac_N    Ras_G-nucl-exch_fac_CS    Ras_GEF_dom    RASGEF_cat_dom    RGL1    Ubiquitin-rel_dom   
Domain families : Pfam (Sanger)RA (PF00788)    RasGEF (PF00617)    RasGEF_N (PF00618)   
Domain families : Pfam (NCBI)pfam00788    pfam00617    pfam00618   
Domain families : Smart (EMBL)RA (SM00314)  RasGEF (SM00147)  RasGEFN (SM00229)  
Conserved Domain (NCBI)RGL1
DMDM Disease mutations23179
Blocks (Seattle)RGL1
SuperfamilyQ9NZL6
Human Protein Atlas [tissue]ENSG00000143344-RGL1 [tissue]
Peptide AtlasQ9NZL6
HPRD12032
IPIIPI00396431   IPI00299679   IPI01015431   IPI01012921   IPI00922151   
Protein Interaction databases
DIP (DOE-UCLA)Q9NZL6
IntAct (EBI)Q9NZL6
FunCoupENSG00000143344
BioGRIDRGL1
STRING (EMBL)RGL1
ZODIACRGL1
Ontologies - Pathways
QuickGOQ9NZL6
Ontology : AmiGOcellular_component  cytosol  small GTPase mediated signal transduction  Ral guanyl-nucleotide exchange factor activity  positive regulation of GTPase activity  
Ontology : EGO-EBIcellular_component  cytosol  small GTPase mediated signal transduction  Ral guanyl-nucleotide exchange factor activity  positive regulation of GTPase activity  
Pathways : KEGGRas signaling pathway   
NDEx NetworkRGL1
Atlas of Cancer Signalling NetworkRGL1
Wikipedia pathwaysRGL1
Orthology - Evolution
OrthoDB23179
GeneTree (enSembl)ENSG00000143344
Phylogenetic Trees/Animal Genes : TreeFamRGL1
HOVERGENQ9NZL6
HOGENOMQ9NZL6
Homologs : HomoloGeneRGL1
Homology/Alignments : Family Browser (UCSC)RGL1
Gene fusions - Rearrangements
Fusion : MitelmanDENND1B/RGL1 [1q31.3/1q25.3]  [t(1;1)(q25;q31)]  
Fusion : MitelmanRGL1/HMCN1 [1q25.3/1q25.3]  [t(1;1)(q25;q25)]  
Fusion : MitelmanVAV3/RGL1 [1p13.3/1q25.3]  [t(1;1)(p13;q25)]  
Fusion: TCGA_MDACCDENND1B 1q31.3 RGL1 1q25.3 LUSC
Fusion: TCGA_MDACCRGL1 1q25.3 HMCN1 1q25.3 SKCM
Fusion: TCGA_MDACCVAV3 1p13.3 RGL1 1q25.3 BRCA
Tumor Fusion PortalRGL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRGL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RGL1
dbVarRGL1
ClinVarRGL1
1000_GenomesRGL1 
Exome Variant ServerRGL1
ExAC (Exome Aggregation Consortium)ENSG00000143344
GNOMAD BrowserENSG00000143344
Genetic variants : HAPMAP23179
Genomic Variants (DGV)RGL1 [DGVbeta]
DECIPHERRGL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRGL1 
Mutations
ICGC Data PortalRGL1 
TCGA Data PortalRGL1 
Broad Tumor PortalRGL1
OASIS PortalRGL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRGL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRGL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RGL1
DgiDB (Drug Gene Interaction Database)RGL1
DoCM (Curated mutations)RGL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RGL1 (select a term)
intoGenRGL1
Cancer3DRGL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605667   
Orphanet
DisGeNETRGL1
MedgenRGL1
Genetic Testing Registry RGL1
NextProtQ9NZL6 [Medical]
TSGene23179
GENETestsRGL1
Target ValidationRGL1
Huge Navigator RGL1 [HugePedia]
snp3D : Map Gene to Disease23179
BioCentury BCIQRGL1
ClinGenRGL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23179
Chemical/Pharm GKB GenePA134934636
Clinical trialRGL1
Miscellaneous
canSAR (ICR)RGL1 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRGL1
EVEXRGL1
GoPubMedRGL1
iHOPRGL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:32:15 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.