Atlas of Genetics and Cytogenetics in Oncology and Haematology

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RGL3 (ral guanine nucleotide dissociation stimulator like 3)

Identity

Alias (NCBI)-
HGNC (Hugo) RGL3
HGNC Alias symbFLJ32585
LocusID (NCBI) 57139
Atlas_Id 42097
Location 19p13.2  [Link to chromosome band 19p13]
Location_base_pair Starts at 11394061 and ends at 11419314 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
RGL3 (19p13.2) / ECSIT (19p13.2)RGL3 (19p13.2) / MALAT1 (11q13.1)RGL3 (19p13.2) / QPCT (2p22.2)
ZNF14 (19p13.11) / RGL3 (19p13.2)RGL3 19p13.2 / ECSIT 19p13.2ZNF14 19p13.11 / RGL3 19p13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)RGL3   30282
Cards
Entrez_Gene (NCBI)RGL3    ral guanine nucleotide dissociation stimulator like 3
Aliases
GeneCards (Weizmann)RGL3
Ensembl hg19 (Hinxton)ENSG00000205517 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000205517 [Gene_View]  ENSG00000205517 [Sequence]  chr19:11394061-11419314 [Contig_View]  RGL3 [Vega]
ICGC DataPortalENSG00000205517
TCGA cBioPortalRGL3
AceView (NCBI)RGL3
Genatlas (Paris)RGL3
SOURCE (Princeton)RGL3
Genetics Home Reference (NIH)RGL3
Genomic and cartography
GoldenPath hg38 (UCSC)RGL3  -     chr19:11394061-11419314 -  19p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RGL3  -     19p13.2   [Description]    (hg19-Feb_2009)
GoldenPathRGL3 - 19p13.2 [CytoView hg19]  RGL3 - 19p13.2 [CytoView hg38]
ImmunoBaseENSG00000205517
genome Data Viewer NCBIRGL3 [Mapview hg19]  
OMIM616743   
Gene and transcription
Genbank (Entrez)AK057147 AK096811 AK126263 AK293404 AK298281
RefSeq transcript (Entrez)NM_001035223 NM_001161616
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RGL3
Alternative Splicing GalleryENSG00000205517
Gene ExpressionRGL3 [ NCBI-GEO ]   RGL3 [ EBI - ARRAY_EXPRESS ]   RGL3 [ SEEK ]   RGL3 [ MEM ]
Gene Expression Viewer (FireBrowse)RGL3 [ Firebrowse - Broad ]
GenevisibleExpression of RGL3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57139
GTEX Portal (Tissue expression)RGL3
Human Protein AtlasENSG00000205517-RGL3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ3MIN7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ3MIN7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ3MIN7
Splice isoforms : SwissVarQ3MIN7
PhosPhoSitePlusQ3MIN7
Domaine pattern : Prosite (Expaxy)RA (PS50200)    RASGEF (PS00720)    RASGEF_CAT (PS50009)    RASGEF_NTER (PS50212)   
Domains : Interpro (EBI)RA_dom    Ras-like_GEF    Ras-like_Gua-exchang_fac_N    Ras_G-nucl-exch_fac_CS    Ras_GEF_dom_sf    RASGEF_cat_dom    RASGEF_cat_dom_sf    RGL3    Ubiquitin-like_domsf   
Domain families : Pfam (Sanger)RA (PF00788)    RasGEF (PF00617)    RasGEF_N (PF00618)   
Domain families : Pfam (NCBI)pfam00788    pfam00617    pfam00618   
Domain families : Smart (EMBL)RA (SM00314)  RasGEF (SM00147)  RasGEFN (SM00229)  
Conserved Domain (NCBI)RGL3
Blocks (Seattle)RGL3
SuperfamilyQ3MIN7
Human Protein Atlas [tissue]ENSG00000205517-RGL3 [tissue]
Peptide AtlasQ3MIN7
IPIIPI00643373   IPI00641225   IPI00908940   IPI00930050   IPI00747325   
Protein Interaction databases
DIP (DOE-UCLA)Q3MIN7
IntAct (EBI)Q3MIN7
BioGRIDRGL3
STRING (EMBL)RGL3
ZODIACRGL3
Ontologies - Pathways
QuickGOQ3MIN7
Ontology : AmiGOguanyl-nucleotide exchange factor activity  protein binding  small GTPase mediated signal transduction  small GTPase binding  positive regulation of GTPase activity  
Ontology : EGO-EBIguanyl-nucleotide exchange factor activity  protein binding  small GTPase mediated signal transduction  small GTPase binding  positive regulation of GTPase activity  
NDEx NetworkRGL3
Atlas of Cancer Signalling NetworkRGL3
Wikipedia pathwaysRGL3
Orthology - Evolution
OrthoDB57139
GeneTree (enSembl)ENSG00000205517
Phylogenetic Trees/Animal Genes : TreeFamRGL3
HOGENOMQ3MIN7
Homologs : HomoloGeneRGL3
Homology/Alignments : Family Browser (UCSC)RGL3
Gene fusions - Rearrangements
Fusion : MitelmanRGL3/ECSIT [19p13.2/19p13.2]  
Fusion : MitelmanZNF14/RGL3 [19p13.11/19p13.2]  
Fusion PortalRGL3 19p13.2 ECSIT 19p13.2 BRCA
Fusion PortalZNF14 19p13.11 RGL3 19p13.2 BRCA
Fusion : QuiverRGL3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRGL3 [hg38]
dbVarRGL3
ClinVarRGL3
MonarchRGL3
1000_GenomesRGL3 
Exome Variant ServerRGL3
GNOMAD BrowserENSG00000205517
Varsome BrowserRGL3
Genomic Variants (DGV)RGL3 [DGVbeta]
DECIPHERRGL3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRGL3 
Mutations
ICGC Data PortalRGL3 
TCGA Data PortalRGL3 
Broad Tumor PortalRGL3
OASIS PortalRGL3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRGL3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRGL3
Mutations and Diseases : HGMDRGL3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RGL3
DgiDB (Drug Gene Interaction Database)RGL3
DoCM (Curated mutations)RGL3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RGL3 (select a term)
intoGenRGL3
Cancer3DRGL3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616743   
Orphanet
DisGeNETRGL3
MedgenRGL3
Genetic Testing Registry RGL3
NextProtQ3MIN7 [Medical]
GENETestsRGL3
Target ValidationRGL3
Huge Navigator RGL3 [HugePedia]
ClinGenRGL3
Clinical trials, drugs, therapy
MyCancerGenomeRGL3
Protein Interactions : CTD
Pharm GKB GenePA134979213
PharosQ3MIN7
Clinical trialRGL3
Miscellaneous
canSAR (ICR)RGL3 (select the gene name)
HarmonizomeRGL3
DataMed IndexRGL3
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRGL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 25 19:43:08 CET 2021
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