Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6002
MIM: 602512
HGNC: 9994
Ensembl: ENSG00000159788
Variants:
dbSNP: 6002
ClinVar: 6002
TCGA: ENSG00000159788
COSMIC: RGS12
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by GPCR | REACTOME | R-HSA-372790 |
| GPCR downstream signaling | REACTOME | R-HSA-388396 |
| G alpha (i) signalling events | REACTOME | R-HSA-418594 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36797232 | 2023 | RGS12 represses oral squamous cell carcinoma by driving M1 polarization of tumor-associated macrophages via controlling ciliary MYCBP2/KIF2A signaling. | 1 |
| 36797232 | 2023 | RGS12 represses oral squamous cell carcinoma by driving M1 polarization of tumor-associated macrophages via controlling ciliary MYCBP2/KIF2A signaling. | 1 |
| 34796776 | 2022 | RGS12 Drives Macrophage Activation and Osteoclastogenesis in Periodontitis. | 8 |
| 34931491 | 2022 | RGS12 inhibits the progression and metastasis of multiple myeloma by driving M1 macrophage polarization and activation in the bone marrow microenvironment. | 6 |
| 34796776 | 2022 | RGS12 Drives Macrophage Activation and Osteoclastogenesis in Periodontitis. | 8 |
| 34931491 | 2022 | RGS12 inhibits the progression and metastasis of multiple myeloma by driving M1 macrophage polarization and activation in the bone marrow microenvironment. | 6 |
| 33198557 | 2021 | RGS12 Represses Oral Cancer via the Phosphorylation and SUMOylation of PTEN. | 11 |
| 33686240 | 2021 | RGS12 is a novel tumor suppressor in osteosarcoma that inhibits YAP-TEAD1-Ezrin signaling. | 18 |
| 33198557 | 2021 | RGS12 Represses Oral Cancer via the Phosphorylation and SUMOylation of PTEN. | 11 |
| 33686240 | 2021 | RGS12 is a novel tumor suppressor in osteosarcoma that inhibits YAP-TEAD1-Ezrin signaling. | 18 |
| 28611045 | 2017 | RGS12 Is a Novel Tumor-Suppressor Gene in African American Prostate Cancer That Represses AKT and MNX1 Expression. | 22 |
| 28611045 | 2017 | RGS12 Is a Novel Tumor-Suppressor Gene in African American Prostate Cancer That Represses AKT and MNX1 Expression. | 22 |
| 26987813 | 2016 | Regulator of G-protein signalling and GoLoco proteins suppress TRPC4 channel function via acting at Gαi/o. | 5 |
| 26987813 | 2016 | Regulator of G-protein signalling and GoLoco proteins suppress TRPC4 channel function via acting at Gαi/o. | 5 |
| 19851296 | 2010 | Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. | 7 |
Citation
Dessen P
RGS12 (regulator of G protein signaling 12)
Atlas Genet Cytogenet Oncol Haematol. 2003-12-01
Online version: http://atlasgeneticsoncology.org/gene/42100/rgs12
