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RGS16 (regulator of G protein signaling 16)

Identity

Alias_namesregulator of G-protein signalling 16
Alias_symbol (synonym)A28-RGS14
RGS-r
Other aliasA28-RGS14P
RGS-R
HGNC (Hugo) RGS16
LocusID (NCBI) 6004
Atlas_Id 42101
Location 1q25.3  [Link to chromosome band 1q25]
Location_base_pair Starts at 182598623 and ends at 182604413 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  dup(1q) in ALL


External links

Nomenclature
HGNC (Hugo)RGS16   9997
Cards
Entrez_Gene (NCBI)RGS16  6004  regulator of G protein signaling 16
AliasesA28-RGS14; A28-RGS14P; RGS-R
GeneCards (Weizmann)RGS16
Ensembl hg19 (Hinxton)ENSG00000143333 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000143333 [Gene_View]  chr1:182598623-182604413 [Contig_View]  RGS16 [Vega]
ICGC DataPortalENSG00000143333
TCGA cBioPortalRGS16
AceView (NCBI)RGS16
Genatlas (Paris)RGS16
WikiGenes6004
SOURCE (Princeton)RGS16
Genetics Home Reference (NIH)RGS16
Genomic and cartography
GoldenPath hg38 (UCSC)RGS16  -     chr1:182598623-182604413 -  1q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RGS16  -     1q25.3   [Description]    (hg19-Feb_2009)
EnsemblRGS16 - 1q25.3 [CytoView hg19]  RGS16 - 1q25.3 [CytoView hg38]
Mapping of homologs : NCBIRGS16 [Mapview hg19]  RGS16 [Mapview hg38]
OMIM602514   
Gene and transcription
Genbank (Entrez)AF493937 AK301261 AK311880 AW193671 BC006243
RefSeq transcript (Entrez)NM_002928
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RGS16
Cluster EST : UnigeneHs.413297 [ NCBI ]
CGAP (NCI)Hs.413297
Alternative Splicing GalleryENSG00000143333
Gene ExpressionRGS16 [ NCBI-GEO ]   RGS16 [ EBI - ARRAY_EXPRESS ]   RGS16 [ SEEK ]   RGS16 [ MEM ]
Gene Expression Viewer (FireBrowse)RGS16 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6004
GTEX Portal (Tissue expression)RGS16
Human Protein AtlasENSG00000143333-RGS16 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15492   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15492  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15492
Splice isoforms : SwissVarO15492
PhosPhoSitePlusO15492
Domaine pattern : Prosite (Expaxy)RGS (PS50132)   
Domains : Interpro (EBI)RGS    RGS_subdom1   
Domain families : Pfam (Sanger)RGS (PF00615)   
Domain families : Pfam (NCBI)pfam00615   
Domain families : Smart (EMBL)RGS (SM00315)  
Conserved Domain (NCBI)RGS16
DMDM Disease mutations6004
Blocks (Seattle)RGS16
PDB (SRS)2BT2    2IK8   
PDB (PDBSum)2BT2    2IK8   
PDB (IMB)2BT2    2IK8   
PDB (RSDB)2BT2    2IK8   
Structural Biology KnowledgeBase2BT2    2IK8   
SCOP (Structural Classification of Proteins)2BT2    2IK8   
CATH (Classification of proteins structures)2BT2    2IK8   
SuperfamilyO15492
Human Protein Atlas [tissue]ENSG00000143333-RGS16 [tissue]
Peptide AtlasO15492
HPRD03945
IPIIPI00289948   
Protein Interaction databases
DIP (DOE-UCLA)O15492
IntAct (EBI)O15492
FunCoupENSG00000143333
BioGRIDRGS16
STRING (EMBL)RGS16
ZODIACRGS16
Ontologies - Pathways
QuickGOO15492
Ontology : AmiGOGTPase activator activity  protein binding  calmodulin binding  cytoplasm  plasma membrane  G-protein coupled receptor signaling pathway  visual perception  regulation of G-protein coupled receptor protein signaling pathway  negative regulation of signal transduction  intrinsic component of membrane  positive regulation of GTPase activity  
Ontology : EGO-EBIGTPase activator activity  protein binding  calmodulin binding  cytoplasm  plasma membrane  G-protein coupled receptor signaling pathway  visual perception  regulation of G-protein coupled receptor protein signaling pathway  negative regulation of signal transduction  intrinsic component of membrane  positive regulation of GTPase activity  
NDEx NetworkRGS16
Atlas of Cancer Signalling NetworkRGS16
Wikipedia pathwaysRGS16
Orthology - Evolution
OrthoDB6004
GeneTree (enSembl)ENSG00000143333
Phylogenetic Trees/Animal Genes : TreeFamRGS16
HOVERGENO15492
HOGENOMO15492
Homologs : HomoloGeneRGS16
Homology/Alignments : Family Browser (UCSC)RGS16
Gene fusions - Rearrangements
Fusion: Tumor Portal RGS16
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRGS16 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RGS16
dbVarRGS16
ClinVarRGS16
1000_GenomesRGS16 
Exome Variant ServerRGS16
ExAC (Exome Aggregation Consortium)ENSG00000143333
GNOMAD BrowserENSG00000143333
Genetic variants : HAPMAP6004
Genomic Variants (DGV)RGS16 [DGVbeta]
DECIPHERRGS16 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRGS16 
Mutations
ICGC Data PortalRGS16 
TCGA Data PortalRGS16 
Broad Tumor PortalRGS16
OASIS PortalRGS16 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRGS16  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRGS16
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RGS16
DgiDB (Drug Gene Interaction Database)RGS16
DoCM (Curated mutations)RGS16 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RGS16 (select a term)
intoGenRGS16
Cancer3DRGS16(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602514   
Orphanet
MedgenRGS16
Genetic Testing Registry RGS16
NextProtO15492 [Medical]
TSGene6004
GENETestsRGS16
Target ValidationRGS16
Huge Navigator RGS16 [HugePedia]
snp3D : Map Gene to Disease6004
BioCentury BCIQRGS16
ClinGenRGS16
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6004
Chemical/Pharm GKB GenePA34367
Clinical trialRGS16
Miscellaneous
canSAR (ICR)RGS16 (select the gene name)
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRGS16
EVEXRGS16
GoPubMedRGS16
iHOPRGS16
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 13:08:36 CET 2017

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