Identity
HGNC
LOCATION
20q13.33
LOCUSID
ALIAS
GAIP,RGSGAIP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10287
MIM: 605071
HGNC: 13735
Ensembl: ENSG00000171700
Variants:
dbSNP: 10287
ClinVar: 10287
TCGA: ENSG00000171700
COSMIC: RGS19
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000171700 | ENST00000332298 | P49795 |
| ENSG00000171700 | ENST00000395042 | P49795 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA445043 | Opioid-Related Disorders | Disease | ClinicalAnnotation | associated | PD | ||
| PA452618 | opioids | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34482807 | 2021 | Genome-wide screening for the G-protein-coupled receptor (GPCR) pathway-related therapeutic gene RGS19 (regulator of G protein signaling 19) in bladder cancer. | 7 |
| 34482807 | 2021 | Genome-wide screening for the G-protein-coupled receptor (GPCR) pathway-related therapeutic gene RGS19 (regulator of G protein signaling 19) in bladder cancer. | 7 |
| 26116529 | 2015 | RGS19 converts iron deprivation stress into a growth-inhibitory signal. | 1 |
| 26116529 | 2015 | RGS19 converts iron deprivation stress into a growth-inhibitory signal. | 1 |
| 24793302 | 2014 | 5-HT1A receptor-mediated phosphorylation of extracellular signal-regulated kinases (ERK1/2) is modulated by regulator of G protein signaling protein 19. | 7 |
| 24793302 | 2014 | 5-HT1A receptor-mediated phosphorylation of extracellular signal-regulated kinases (ERK1/2) is modulated by regulator of G protein signaling protein 19. | 7 |
| 23416464 | 2013 | RGS19 inhibits Ras signaling through Nm23H1/2-mediated phosphorylation of the kinase suppressor of Ras. | 18 |
| 23799031 | 2013 | Profiling of childhood adversity-associated DNA methylation changes in alcoholic patients and healthy controls. | 33 |
| 23416464 | 2013 | RGS19 inhibits Ras signaling through Nm23H1/2-mediated phosphorylation of the kinase suppressor of Ras. | 18 |
| 23799031 | 2013 | Profiling of childhood adversity-associated DNA methylation changes in alcoholic patients and healthy controls. | 33 |
| 22045062 | 2012 | Elevated expression of RGS19 impairs the responsiveness of stress-activated protein kinases to serum. | 1 |
| 22045062 | 2012 | Elevated expression of RGS19 impairs the responsiveness of stress-activated protein kinases to serum. | 1 |
| 21705135 | 2011 | RGS19 stimulates cell proliferation by deregulating cell cycle control and enhancing Akt signaling. | 16 |
| 21705135 | 2011 | RGS19 stimulates cell proliferation by deregulating cell cycle control and enhancing Akt signaling. | 16 |
| 20468064 | 2010 | Association study of 182 candidate genes in anorexia nervosa. | 32 |
Citation
Dessen P
RGS19 (regulator of G protein signaling 19)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46896/rgs19
