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RGS7 (regulator of G-protein signaling 7)

Identity

Alias_namesregulator of G-protein signalling 7
Other alias-
HGNC (Hugo) RGS7
LocusID (NCBI) 6000
Atlas_Id 45750
Location 1q43  [Link to chromosome band 1q43]
Location_base_pair Starts at 240938814 and ends at 241520530 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
AKT3 (1q43) / RGS7 (1q43)CEP170 (1q43) / RGS7 (1q43)CNST (1q44) / RGS7 (1q43)
LOC652276 (16p13.3) / RGS7 (1q43)RGS7 (1q43) / C8orf34 (8q13.2)RGS7 (1q43) / DNAAF1 (16q23.3)
RGS7 (1q43) / SGSH (17q25.3)AKT3 1q43 / RGS7 1q43CEP170 1q43 / RGS7 1q43
CNST 1q44 / RGS7 1q43RGS7 1q43 / C8orf34 8q13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RGS7   10003
Cards
Entrez_Gene (NCBI)RGS7  6000  regulator of G-protein signaling 7
Aliases
GeneCards (Weizmann)RGS7
Ensembl hg19 (Hinxton)ENSG00000182901 [Gene_View]  chr1:240938814-241520530 [Contig_View]  RGS7 [Vega]
Ensembl hg38 (Hinxton)ENSG00000182901 [Gene_View]  chr1:240938814-241520530 [Contig_View]  RGS7 [Vega]
ICGC DataPortalENSG00000182901
TCGA cBioPortalRGS7
AceView (NCBI)RGS7
Genatlas (Paris)RGS7
WikiGenes6000
SOURCE (Princeton)RGS7
Genetics Home Reference (NIH)RGS7
Genomic and cartography
GoldenPath hg19 (UCSC)RGS7  -     chr1:240938814-241520530 -  1q43   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RGS7  -     1q43   [Description]    (hg38-Dec_2013)
EnsemblRGS7 - 1q43 [CytoView hg19]  RGS7 - 1q43 [CytoView hg38]
Mapping of homologs : NCBIRGS7 [Mapview hg19]  RGS7 [Mapview hg38]
OMIM602517   
Gene and transcription
Genbank (Entrez)AF090116 AF090117 AF493930 AF493931 AK294234
RefSeq transcript (Entrez)NM_001282773 NM_001282775 NM_001282778 NM_002924
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_167186 NW_004929294
Consensus coding sequences : CCDS (NCBI)RGS7
Cluster EST : UnigeneHs.655739 [ NCBI ]
CGAP (NCI)Hs.655739
Alternative Splicing GalleryENSG00000182901
Gene ExpressionRGS7 [ NCBI-GEO ]   RGS7 [ EBI - ARRAY_EXPRESS ]   RGS7 [ SEEK ]   RGS7 [ MEM ]
Gene Expression Viewer (FireBrowse)RGS7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6000
GTEX Portal (Tissue expression)RGS7
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49802   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP49802  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP49802
Splice isoforms : SwissVarP49802
PhosPhoSitePlusP49802
Domaine pattern : Prosite (Expaxy)DEP (PS50186)    RGS (PS50132)   
Domains : Interpro (EBI)DEP_dom    G-protein_gamma-like_dom    RGS    RGS_subdom1    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)DEP (PF00610)    G-gamma (PF00631)    RGS (PF00615)   
Domain families : Pfam (NCBI)pfam00610    pfam00631    pfam00615   
Domain families : Smart (EMBL)DEP (SM00049)  GGL (SM00224)  RGS (SM00315)  
Conserved Domain (NCBI)RGS7
DMDM Disease mutations6000
Blocks (Seattle)RGS7
PDB (SRS)2A72    2D9J   
PDB (PDBSum)2A72    2D9J   
PDB (IMB)2A72    2D9J   
PDB (RSDB)2A72    2D9J   
Structural Biology KnowledgeBase2A72    2D9J   
SCOP (Structural Classification of Proteins)2A72    2D9J   
CATH (Classification of proteins structures)2A72    2D9J   
SuperfamilyP49802
Human Protein AtlasENSG00000182901
Peptide AtlasP49802
HPRD03948
IPIIPI00028457   IPI00257291   IPI00220660   IPI00220661   IPI00874132   IPI00642694   
Protein Interaction databases
DIP (DOE-UCLA)P49802
IntAct (EBI)P49802
FunCoupENSG00000182901
BioGRIDRGS7
STRING (EMBL)RGS7
ZODIACRGS7
Ontologies - Pathways
QuickGOP49802
Ontology : AmiGOsignal transducer activity  GTPase activator activity  cytosol  heterotrimeric G-protein complex  plasma membrane  plasma membrane  protein folding  G-protein coupled receptor signaling pathway  negative regulation of signal transduction  G-protein beta-subunit binding  intracellular signal transduction  positive regulation of GTPase activity  
Ontology : EGO-EBIsignal transducer activity  GTPase activator activity  cytosol  heterotrimeric G-protein complex  plasma membrane  plasma membrane  protein folding  G-protein coupled receptor signaling pathway  negative regulation of signal transduction  G-protein beta-subunit binding  intracellular signal transduction  positive regulation of GTPase activity  
NDEx NetworkRGS7
Atlas of Cancer Signalling NetworkRGS7
Wikipedia pathwaysRGS7
Orthology - Evolution
OrthoDB6000
GeneTree (enSembl)ENSG00000182901
Phylogenetic Trees/Animal Genes : TreeFamRGS7
HOVERGENP49802
HOGENOMP49802
Homologs : HomoloGeneRGS7
Homology/Alignments : Family Browser (UCSC)RGS7
Gene fusions - Rearrangements
Fusion : MitelmanRGS7/C8orf34 [1q43/8q13.2]  
Fusion: TCGAAKT3 1q43 RGS7 1q43 GBM
Fusion: TCGACEP170 1q43 RGS7 1q43 LUAD
Fusion: TCGACNST 1q44 RGS7 1q43 LGG
Fusion: TCGARGS7 1q43 C8orf34 8q13.2 LGG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRGS7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RGS7
dbVarRGS7
ClinVarRGS7
1000_GenomesRGS7 
Exome Variant ServerRGS7
ExAC (Exome Aggregation Consortium)RGS7 (select the gene name)
Genetic variants : HAPMAP6000
Genomic Variants (DGV)RGS7 [DGVbeta]
DECIPHER (Syndromes)1:240938814-241520530  ENSG00000182901
CONAN: Copy Number AnalysisRGS7 
Mutations
ICGC Data PortalRGS7 
TCGA Data PortalRGS7 
Broad Tumor PortalRGS7
OASIS PortalRGS7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRGS7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRGS7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RGS7
DgiDB (Drug Gene Interaction Database)RGS7
DoCM (Curated mutations)RGS7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RGS7 (select a term)
intoGenRGS7
Cancer3DRGS7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602517   
Orphanet
MedgenRGS7
Genetic Testing Registry RGS7
NextProtP49802 [Medical]
TSGene6000
GENETestsRGS7
Huge Navigator RGS7 [HugePedia]
snp3D : Map Gene to Disease6000
BioCentury BCIQRGS7
ClinGenRGS7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6000
Chemical/Pharm GKB GenePA34378
Clinical trialRGS7
Miscellaneous
canSAR (ICR)RGS7 (select the gene name)
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRGS7
EVEXRGS7
GoPubMedRGS7
iHOPRGS7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:24:59 CET 2017

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