RGS7BP (regulator of G protein signaling 7 binding protein)

2014-11-01  

Identity

HGNC
RGS7BP
LOCATION
5q12.3
LOCUSID
401190
ALIAS
R7BP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 401190
MIM: 610890
HGNC: 23271
Ensembl: ENSG00000186479

Variants:

dbSNP: 401190
ClinVar: 401190
TCGA: ENSG00000186479
COSMIC: RGS7BP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000186479ENST00000334025Q6MZT1

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
168679772006R7BP augments the function of RGS7*Gbeta5 complexes by a plasma membrane-targeting mechanism.44
268959612016Regulator of G Protein Signaling 7 (RGS7) Can Exist in a Homo-oligomeric Form That Is Regulated by Gαo and R7-binding Protein.4
284321242017Regulation of neurite morphogenesis by interaction between R7 regulator of G protein signaling complexes and G protein subunit Gα13.3
305402502018Structural organization of a major neuronal G protein regulator, the RGS7-Gβ5-R7BP complex.3
194973062009RGS11 interacts preferentially with R7BP over Galpha(oa)--characterization of Gbeta5-free RGS11.1
214578772011Association analysis of RGS7BP gene polymorphisms with aspirin intolerance in asthmatic patients.0

Citation

Dessen P

RGS7BP (regulator of G protein signaling 7 binding protein)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72619/rgs7bp