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RGS8 (regulator of G protein signaling 8)

Identity

Alias (NCBI)-
HGNC (Hugo) RGS8
HGNC Alias symbMGC119067
MGC119068
MGC119069
HGNC Previous nameregulator of G-protein signalling 8
 regulator of G-protein signaling 8
LocusID (NCBI) 85397
Atlas_Id 47429
Location 1q25.3  [Link to chromosome band 1q25]
Location_base_pair Starts at 182641814 and ends at 182672932 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADIPOR1 (1q32.1) / RGS8 (1q25.3)ADIPOR1 1q32.1 / RGS8 1q25.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)RGS8   16810
Cards
Entrez_Gene (NCBI)RGS8    regulator of G protein signaling 8
Aliases
GeneCards (Weizmann)RGS8
Ensembl hg19 (Hinxton)ENSG00000135824 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135824 [Gene_View]  ENSG00000135824 [Sequence]  chr1:182641814-182672932 [Contig_View]  RGS8 [Vega]
ICGC DataPortalENSG00000135824
TCGA cBioPortalRGS8
AceView (NCBI)RGS8
Genatlas (Paris)RGS8
SOURCE (Princeton)RGS8
Genetics Home Reference (NIH)RGS8
Genomic and cartography
GoldenPath hg38 (UCSC)RGS8  -     chr1:182641814-182672932 -  1q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RGS8  -     1q25.3   [Description]    (hg19-Feb_2009)
GoldenPathRGS8 - 1q25.3 [CytoView hg19]  RGS8 - 1q25.3 [CytoView hg38]
ImmunoBaseENSG00000135824
genome Data Viewer NCBIRGS8 [Mapview hg19]  
OMIM607189   
Gene and transcription
Genbank (Entrez)AF300649 AH010175 AI209102 AK057753 AK294660
RefSeq transcript (Entrez)NM_001102450 NM_001369564 NM_001387847 NM_001387848 NM_001387849 NM_033345
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RGS8
Alternative Splicing GalleryENSG00000135824
Gene ExpressionRGS8 [ NCBI-GEO ]   RGS8 [ EBI - ARRAY_EXPRESS ]   RGS8 [ SEEK ]   RGS8 [ MEM ]
Gene Expression Viewer (FireBrowse)RGS8 [ Firebrowse - Broad ]
GenevisibleExpression of RGS8 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)85397
GTEX Portal (Tissue expression)RGS8
Human Protein AtlasENSG00000135824-RGS8 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP57771   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP57771  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP57771
Splice isoforms : SwissVarP57771
PhosPhoSitePlusP57771
Domaine pattern : Prosite (Expaxy)RGS (PS50132)   
Domains : Interpro (EBI)RGS    RGS8    RGS_RGS8    RGS_sf    RGS_subdom1/3   
Domain families : Pfam (Sanger)RGS (PF00615)   
Domain families : Pfam (NCBI)pfam00615   
Domain families : Smart (EMBL)RGS (SM00315)  
Conserved Domain (NCBI)RGS8
Blocks (Seattle)RGS8
PDB (RSDB)2IHD    2ODE    5DO9   
PDB Europe2IHD    2ODE    5DO9   
PDB (PDBSum)2IHD    2ODE    5DO9   
PDB (IMB)2IHD    2ODE    5DO9   
Structural Biology KnowledgeBase2IHD    2ODE    5DO9   
SCOP (Structural Classification of Proteins)2IHD    2ODE    5DO9   
CATH (Classification of proteins structures)2IHD    2ODE    5DO9   
SuperfamilyP57771
Human Protein Atlas [tissue]ENSG00000135824-RGS8 [tissue]
Peptide AtlasP57771
HPRD06221
IPIIPI00855716   IPI00100471   IPI00966740   
Protein Interaction databases
DIP (DOE-UCLA)P57771
IntAct (EBI)P57771
BioGRIDRGS8
STRING (EMBL)RGS8
ZODIACRGS8
Ontologies - Pathways
QuickGOP57771
Ontology : AmiGOGTPase activity  GTPase activator activity  protein binding  nucleus  plasma membrane  G protein-coupled receptor signaling pathway  G protein-coupled acetylcholine receptor signaling pathway  negative regulation of signal transduction  dendrite  extrinsic component of cytoplasmic side of plasma membrane  neuronal cell body membrane  perikaryon  positive regulation of GTPase activity  synapse  regulation of dopamine receptor signaling pathway  
Ontology : EGO-EBIGTPase activity  GTPase activator activity  protein binding  nucleus  plasma membrane  G protein-coupled receptor signaling pathway  G protein-coupled acetylcholine receptor signaling pathway  negative regulation of signal transduction  dendrite  extrinsic component of cytoplasmic side of plasma membrane  neuronal cell body membrane  perikaryon  positive regulation of GTPase activity  synapse  regulation of dopamine receptor signaling pathway  
NDEx NetworkRGS8
Atlas of Cancer Signalling NetworkRGS8
Wikipedia pathwaysRGS8
Orthology - Evolution
OrthoDB85397
GeneTree (enSembl)ENSG00000135824
Phylogenetic Trees/Animal Genes : TreeFamRGS8
HOGENOMP57771
Homologs : HomoloGeneRGS8
Homology/Alignments : Family Browser (UCSC)RGS8
Gene fusions - Rearrangements
Fusion : MitelmanADIPOR1/RGS8 [1q32.1/1q25.3]  
Fusion PortalADIPOR1 1q32.1 RGS8 1q25.3 BRCA
Fusion : QuiverRGS8
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRGS8 [hg38]
dbVarRGS8
ClinVarRGS8
MonarchRGS8
1000_GenomesRGS8 
Exome Variant ServerRGS8
GNOMAD BrowserENSG00000135824
Varsome BrowserRGS8
Genomic Variants (DGV)RGS8 [DGVbeta]
DECIPHERRGS8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRGS8 
Mutations
ICGC Data PortalRGS8 
TCGA Data PortalRGS8 
Broad Tumor PortalRGS8
OASIS PortalRGS8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRGS8  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRGS8
Mutations and Diseases : HGMDRGS8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RGS8
DgiDB (Drug Gene Interaction Database)RGS8
DoCM (Curated mutations)RGS8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RGS8 (select a term)
intoGenRGS8
Cancer3DRGS8(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607189   
Orphanet
DisGeNETRGS8
MedgenRGS8
Genetic Testing Registry RGS8
NextProtP57771 [Medical]
GENETestsRGS8
Target ValidationRGS8
Huge Navigator RGS8 [HugePedia]
ClinGenRGS8
Clinical trials, drugs, therapy
MyCancerGenomeRGS8
Protein Interactions : CTD
Pharm GKB GenePA34379
PharosP57771
Clinical trialRGS8
Miscellaneous
canSAR (ICR)RGS8 (select the gene name)
HarmonizomeRGS8
DataMed IndexRGS8
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRGS8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 25 19:43:13 CET 2021

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