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RGSL1 (regulator of G protein signaling like 1)

Identity

Alias_namesRGSL2
regulator of G-protein signalling like 1
regulator of G-protein signaling like 2
regulator of G-protein signalling like 2
Other aliasRGSL
HGNC (Hugo) RGSL1
LocusID (NCBI) 353299
Atlas_Id 47266
Location 1q25.3  [Link to chromosome band 1q25]
Location_base_pair Starts at 182450121 and ends at 182560598 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RGSL1   18636
Cards
Entrez_Gene (NCBI)RGSL1  353299  regulator of G protein signaling like 1
AliasesRGSL; RGSL2
GeneCards (Weizmann)RGSL1
Ensembl hg19 (Hinxton)ENSG00000121446 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000121446 [Gene_View]  chr1:182450121-182560598 [Contig_View]  RGSL1 [Vega]
ICGC DataPortalENSG00000121446
TCGA cBioPortalRGSL1
AceView (NCBI)RGSL1
Genatlas (Paris)RGSL1
WikiGenes353299
SOURCE (Princeton)RGSL1
Genetics Home Reference (NIH)RGSL1
Genomic and cartography
GoldenPath hg38 (UCSC)RGSL1  -     chr1:182450121-182560598 +  1q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RGSL1  -     1q25.3   [Description]    (hg19-Feb_2009)
EnsemblRGSL1 - 1q25.3 [CytoView hg19]  RGSL1 - 1q25.3 [CytoView hg38]
Mapping of homologs : NCBIRGSL1 [Mapview hg19]  RGSL1 [Mapview hg38]
OMIM611012   
Gene and transcription
Genbank (Entrez)AF508902 AF510428 AK128152 AK302768 AL136902
RefSeq transcript (Entrez)NM_001137669 NM_032267 NM_181572
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RGSL1
Cluster EST : UnigeneHs.121200 [ NCBI ]
CGAP (NCI)Hs.121200
Alternative Splicing GalleryENSG00000121446
Gene ExpressionRGSL1 [ NCBI-GEO ]   RGSL1 [ EBI - ARRAY_EXPRESS ]   RGSL1 [ SEEK ]   RGSL1 [ MEM ]
Gene Expression Viewer (FireBrowse)RGSL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)353299
GTEX Portal (Tissue expression)RGSL1
Human Protein AtlasENSG00000121446-RGSL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtA5PLK6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA5PLK6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA5PLK6
Splice isoforms : SwissVarA5PLK6
PhosPhoSitePlusA5PLK6
Domains : Interpro (EBI)RGS   
Domain families : Pfam (Sanger)RGS (PF00615)   
Domain families : Pfam (NCBI)pfam00615   
Conserved Domain (NCBI)RGSL1
DMDM Disease mutations353299
Blocks (Seattle)RGSL1
SuperfamilyA5PLK6
Human Protein Atlas [tissue]ENSG00000121446-RGSL1 [tissue]
Peptide AtlasA5PLK6
HPRD17971
IPIIPI00104396   IPI00902598   IPI00871887   IPI00902937   IPI00902436   IPI00031058   
Protein Interaction databases
DIP (DOE-UCLA)A5PLK6
IntAct (EBI)A5PLK6
FunCoupENSG00000121446
BioGRIDRGSL1
STRING (EMBL)RGSL1
ZODIACRGSL1
Ontologies - Pathways
QuickGOA5PLK6
Ontology : AmiGOGTPase activator activity  cytoplasm  plasma membrane  integral component of membrane  positive regulation of GTPase activity  
Ontology : EGO-EBIGTPase activator activity  cytoplasm  plasma membrane  integral component of membrane  positive regulation of GTPase activity  
NDEx NetworkRGSL1
Atlas of Cancer Signalling NetworkRGSL1
Wikipedia pathwaysRGSL1
Orthology - Evolution
OrthoDB353299
GeneTree (enSembl)ENSG00000121446
Phylogenetic Trees/Animal Genes : TreeFamRGSL1
HOVERGENA5PLK6
HOGENOMA5PLK6
Homologs : HomoloGeneRGSL1
Homology/Alignments : Family Browser (UCSC)RGSL1
Gene fusions - Rearrangements
Tumor Fusion PortalRGSL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRGSL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RGSL1
dbVarRGSL1
ClinVarRGSL1
1000_GenomesRGSL1 
Exome Variant ServerRGSL1
ExAC (Exome Aggregation Consortium)ENSG00000121446
GNOMAD BrowserENSG00000121446
Genetic variants : HAPMAP353299
Genomic Variants (DGV)RGSL1 [DGVbeta]
DECIPHERRGSL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRGSL1 
Mutations
ICGC Data PortalRGSL1 
TCGA Data PortalRGSL1 
Broad Tumor PortalRGSL1
OASIS PortalRGSL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRGSL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRGSL1
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch RGSL1
DgiDB (Drug Gene Interaction Database)RGSL1
DoCM (Curated mutations)RGSL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RGSL1 (select a term)
intoGenRGSL1
Cancer3DRGSL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611012   
Orphanet
DisGeNETRGSL1
MedgenRGSL1
Genetic Testing Registry RGSL1
NextProtA5PLK6 [Medical]
TSGene353299
GENETestsRGSL1
Target ValidationRGSL1
Huge Navigator RGSL1 [HugePedia]
snp3D : Map Gene to Disease353299
BioCentury BCIQRGSL1
ClinGenRGSL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD353299
Chemical/Pharm GKB GenePA134870196
Clinical trialRGSL1
Miscellaneous
canSAR (ICR)RGSL1 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRGSL1
EVEXRGSL1
GoPubMedRGSL1
iHOPRGSL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:32:20 CET 2017

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