RGSL1 (regulator of G protein signaling like 1)

2007-04-01 Affiliation

Identity

HGNC

RGSL1

LOCATION

1q25.3

LOCUSID

353299

ALIAS

RGSL,RGSL2

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 353299
MIM: 611012
HGNC: 18636
Ensembl: ENSG00000121446

Variants:

dbSNP: 353299
ClinVar: 353299
TCGA: ENSG00000121446
COSMIC: RGSL1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000121446	ENST00000294854	A5PLK6
ENSG00000121446	ENST00000415960	H3BNQ0
ENSG00000121446	ENST00000416676	H3BVE8
ENSG00000121446	ENST00000422241	H3BRN5
ENSG00000121446	ENST00000437548	H3BNR3
ENSG00000121446	ENST00000443996	H3BU64
ENSG00000121446	ENST00000447374	H3BNS3
ENSG00000121446	ENST00000634626	A0A0U1RRF3
ENSG00000121446	ENST00000634679	A0A0U1RRF6
ENSG00000121446	ENST00000634723	A0A0U1RRN0
ENSG00000121446	ENST00000634758	A0A0U1RQD8
ENSG00000121446	ENST00000634801	A0A0U1RRG0
ENSG00000121446	ENST00000635407	A0A0U1RRA3
ENSG00000121446	ENST00000648414	A0A3B3ISC9

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Signal Transduction	REACTOME	R-HSA-162582
Signaling by GPCR	REACTOME	R-HSA-372790
GPCR downstream signaling	REACTOME	R-HSA-388396
G alpha (i) signalling events	REACTOME	R-HSA-418594
G alpha (z) signalling events	REACTOME	R-HSA-418597
G alpha (q) signalling events	REACTOME	R-HSA-416476
Gastrin-CREB signalling pathway via PKC and MAPK	REACTOME	R-HSA-881907

References

Pubmed ID	Year	Title	Citations
20574532	2010	Intermediate phenotypes identify divergent pathways to Alzheimer's disease.	24
18521847	2008	A fragile site within the HPC1 region at 1q25.3 affecting RGS16, RGSL1, and RGSL2 in human breast carcinomas.	10
21135262	2011	High-resolution melting analysis for mutation screening of RGSL1, RGS16, and RGS8 in breast cancer.	4
23248035	2013	Chromosome 1q25.3 copy number alterations in primary breast cancers detected by multiplex ligation-dependent probe amplification and allelic imbalance assays and its comparison with fluorescent in situ hybridization assays.	1

Citation

Dessen P

RGSL1 (regulator of G protein signaling like 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47266/rgsl1