Atlas of Genetics and Cytogenetics in Oncology and Haematology


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RHEBL1 (Ras homolog enriched in brain like 1)

Identity

Alias_symbol (synonym)MGC34869
FLJ25797
Other aliasRHEBL1c
HGNC (Hugo) RHEBL1
LocusID (NCBI) 121268
Atlas_Id 43465
Location 12q13.12  [Link to chromosome band 12q13]
Location_base_pair Starts at 49458459 and ends at 49463808 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DHH (12q13.12) / RHEBL1 (12q13.12)KMT2B (19q13.12) / RHEBL1 (12q13.12)KMT2D (12q13.12) / RHEBL1 (12q13.12)
DHH 12q13.12 / RHEBL1 12q13.12MLL2 RHEBL1 12q13.12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RHEBL1   21166
Cards
Entrez_Gene (NCBI)RHEBL1  121268  Ras homolog enriched in brain like 1
AliasesRHEBL1c
GeneCards (Weizmann)RHEBL1
Ensembl hg19 (Hinxton)ENSG00000167550 [Gene_View]  chr12:49458459-49463808 [Contig_View]  RHEBL1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000167550 [Gene_View]  chr12:49458459-49463808 [Contig_View]  RHEBL1 [Vega]
ICGC DataPortalENSG00000167550
TCGA cBioPortalRHEBL1
AceView (NCBI)RHEBL1
Genatlas (Paris)RHEBL1
WikiGenes121268
SOURCE (Princeton)RHEBL1
Genetics Home Reference (NIH)RHEBL1
Genomic and cartography
GoldenPath hg19 (UCSC)RHEBL1  -     chr12:49458459-49463808 -  12q13.12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RHEBL1  -     12q13.12   [Description]    (hg38-Dec_2013)
EnsemblRHEBL1 - 12q13.12 [CytoView hg19]  RHEBL1 - 12q13.12 [CytoView hg38]
Mapping of homologs : NCBIRHEBL1 [Mapview hg19]  RHEBL1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AI917432 AK098663 AY327412 AY509932 BC014155
RefSeq transcript (Entrez)NM_001303126 NM_144593
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_029419 NW_004929384
Consensus coding sequences : CCDS (NCBI)RHEBL1
Cluster EST : UnigeneHs.159013 [ NCBI ]
CGAP (NCI)Hs.159013
Alternative Splicing GalleryENSG00000167550
Gene ExpressionRHEBL1 [ NCBI-GEO ]   RHEBL1 [ EBI - ARRAY_EXPRESS ]   RHEBL1 [ SEEK ]   RHEBL1 [ MEM ]
Gene Expression Viewer (FireBrowse)RHEBL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)121268
GTEX Portal (Tissue expression)RHEBL1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TAI7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TAI7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TAI7
Splice isoforms : SwissVarQ8TAI7
PhosPhoSitePlusQ8TAI7
Domaine pattern : Prosite (Expaxy)RAS (PS51421)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase    Small_GTPase_Ras   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Domain families : Smart (EMBL)RAS (SM00173)  
Conserved Domain (NCBI)RHEBL1
DMDM Disease mutations121268
Blocks (Seattle)RHEBL1
PDB (SRS)3OES   
PDB (PDBSum)3OES   
PDB (IMB)3OES   
PDB (RSDB)3OES   
Structural Biology KnowledgeBase3OES   
SCOP (Structural Classification of Proteins)3OES   
CATH (Classification of proteins structures)3OES   
SuperfamilyQ8TAI7
Human Protein AtlasENSG00000167550
Peptide AtlasQ8TAI7
HPRD15245
IPIIPI00152059   IPI00556561   IPI00942159   IPI01022942   
Protein Interaction databases
DIP (DOE-UCLA)Q8TAI7
IntAct (EBI)Q8TAI7
FunCoupENSG00000167550
BioGRIDRHEBL1
STRING (EMBL)RHEBL1
ZODIACRHEBL1
Ontologies - Pathways
QuickGOQ8TAI7
Ontology : AmiGOprotein binding  GTP binding  cytoplasm  small GTPase mediated signal transduction  endomembrane system  protein transport  membrane  TOR signaling  metal ion binding  positive regulation of NF-kappaB transcription factor activity  
Ontology : EGO-EBIprotein binding  GTP binding  cytoplasm  small GTPase mediated signal transduction  endomembrane system  protein transport  membrane  TOR signaling  metal ion binding  positive regulation of NF-kappaB transcription factor activity  
NDEx NetworkRHEBL1
Atlas of Cancer Signalling NetworkRHEBL1
Wikipedia pathwaysRHEBL1
Orthology - Evolution
OrthoDB121268
GeneTree (enSembl)ENSG00000167550
Phylogenetic Trees/Animal Genes : TreeFamRHEBL1
HOVERGENQ8TAI7
HOGENOMQ8TAI7
Homologs : HomoloGeneRHEBL1
Homology/Alignments : Family Browser (UCSC)RHEBL1
Gene fusions - Rearrangements
Fusion : MitelmanDHH/RHEBL1 [12q13.12/12q13.12]  [del(12)(q13q13)]  
Fusion : MitelmanKMT2B/RHEBL1 [19q13.12/12q13.12]  [t(12;12)(q13;q13)]  
Fusion: TCGAMLL2 RHEBL1 12q13.12 OV
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRHEBL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RHEBL1
dbVarRHEBL1
ClinVarRHEBL1
1000_GenomesRHEBL1 
Exome Variant ServerRHEBL1
ExAC (Exome Aggregation Consortium)RHEBL1 (select the gene name)
Genetic variants : HAPMAP121268
Genomic Variants (DGV)RHEBL1 [DGVbeta]
DECIPHER (Syndromes)12:49458459-49463808  ENSG00000167550
CONAN: Copy Number AnalysisRHEBL1 
Mutations
ICGC Data PortalRHEBL1 
TCGA Data PortalRHEBL1 
Broad Tumor PortalRHEBL1
OASIS PortalRHEBL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRHEBL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRHEBL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RHEBL1
DgiDB (Drug Gene Interaction Database)RHEBL1
DoCM (Curated mutations)RHEBL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RHEBL1 (select a term)
intoGenRHEBL1
Cancer3DRHEBL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenRHEBL1
Genetic Testing Registry RHEBL1
NextProtQ8TAI7 [Medical]
TSGene121268
GENETestsRHEBL1
Huge Navigator RHEBL1 [HugePedia]
snp3D : Map Gene to Disease121268
BioCentury BCIQRHEBL1
ClinGenRHEBL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD121268
Chemical/Pharm GKB GenePA134984759
Clinical trialRHEBL1
Miscellaneous
canSAR (ICR)RHEBL1 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRHEBL1
EVEXRHEBL1
GoPubMedRHEBL1
iHOPRHEBL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:25:01 CET 2017

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