Atlas of Genetics and Cytogenetics in Oncology and Haematology


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RHOQ (ras homolog family member Q)

Identity

Alias_namesRASL7A
ARHQ
RAS-like, family 7, member A
ras homolog gene family, member Q
Alias_symbol (synonym)TC10
Other aliasHEL-S-42
TC10A
HGNC (Hugo) RHOQ
LocusID (NCBI) 23433
Atlas_Id 42113
Location 2p21  [Link to chromosome band 2p21]
Location_base_pair Starts at 46542728 and ends at 46584688 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CKLF-CMTM1 (16q21) / RHOQ (2p21)RHOQ (2p21) / ALDH1L1 (3q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RHOQ   17736
Cards
Entrez_Gene (NCBI)RHOQ  23433  ras homolog family member Q
AliasesARHQ; HEL-S-42; RASL7A; TC10; 
TC10A
GeneCards (Weizmann)RHOQ
Ensembl hg19 (Hinxton)ENSG00000119729 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000119729 [Gene_View]  chr2:46542728-46584688 [Contig_View]  RHOQ [Vega]
ICGC DataPortalENSG00000119729
TCGA cBioPortalRHOQ
AceView (NCBI)RHOQ
Genatlas (Paris)RHOQ
WikiGenes23433
SOURCE (Princeton)RHOQ
Genetics Home Reference (NIH)RHOQ
Genomic and cartography
GoldenPath hg38 (UCSC)RHOQ  -     chr2:46542728-46584688 +  2p21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RHOQ  -     2p21   [Description]    (hg19-Feb_2009)
EnsemblRHOQ - 2p21 [CytoView hg19]  RHOQ - 2p21 [CytoView hg38]
Mapping of homologs : NCBIRHOQ [Mapview hg19]  RHOQ [Mapview hg38]
OMIM605857   
Gene and transcription
Genbank (Entrez)AF498976 AK095329 BC013135 BC033251 BC056154
RefSeq transcript (Entrez)NM_012249
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RHOQ
Cluster EST : UnigeneHs.709193 [ NCBI ]
CGAP (NCI)Hs.709193
Alternative Splicing GalleryENSG00000119729
Gene ExpressionRHOQ [ NCBI-GEO ]   RHOQ [ EBI - ARRAY_EXPRESS ]   RHOQ [ SEEK ]   RHOQ [ MEM ]
Gene Expression Viewer (FireBrowse)RHOQ [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23433
GTEX Portal (Tissue expression)RHOQ
Protein : pattern, domain, 3D structure
UniProt/SwissProtP17081   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP17081  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP17081
Splice isoforms : SwissVarP17081
PhosPhoSitePlusP17081
Domaine pattern : Prosite (Expaxy)RHO (PS51420)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Conserved Domain (NCBI)RHOQ
DMDM Disease mutations23433
Blocks (Seattle)RHOQ
PDB (SRS)2ATX   
PDB (PDBSum)2ATX   
PDB (IMB)2ATX   
PDB (RSDB)2ATX   
Structural Biology KnowledgeBase2ATX   
SCOP (Structural Classification of Proteins)2ATX   
CATH (Classification of proteins structures)2ATX   
SuperfamilyP17081
Human Protein AtlasENSG00000119729
Peptide AtlasP17081
HPRD05791
IPIIPI00012511   IPI00983228   IPI00880127   IPI00981858   IPI00982470   
Protein Interaction databases
DIP (DOE-UCLA)P17081
IntAct (EBI)P17081
FunCoupENSG00000119729
BioGRIDRHOQ
STRING (EMBL)RHOQ
ZODIACRHOQ
Ontologies - Pathways
QuickGOP17081
Ontology : AmiGOGTPase activity  profilin binding  GTP binding  cytosol  actin filament  plasma membrane  plasma membrane  small GTPase mediated signal transduction  insulin receptor signaling pathway  regulation of cell shape  Golgi-associated vesicle membrane  cortical actin cytoskeleton organization  GBD domain binding  cellular response to insulin stimulus  regulation of actin cytoskeleton organization  membrane raft  positive regulation of transcription from RNA polymerase II promoter  GTP metabolic process  positive regulation of glucose import  regulation of small GTPase mediated signal transduction  positive regulation of filopodium assembly  extracellular exosome  negative regulation of establishment of protein localization to plasma membrane  
Ontology : EGO-EBIGTPase activity  profilin binding  GTP binding  cytosol  actin filament  plasma membrane  plasma membrane  small GTPase mediated signal transduction  insulin receptor signaling pathway  regulation of cell shape  Golgi-associated vesicle membrane  cortical actin cytoskeleton organization  GBD domain binding  cellular response to insulin stimulus  regulation of actin cytoskeleton organization  membrane raft  positive regulation of transcription from RNA polymerase II promoter  GTP metabolic process  positive regulation of glucose import  regulation of small GTPase mediated signal transduction  positive regulation of filopodium assembly  extracellular exosome  negative regulation of establishment of protein localization to plasma membrane  
Pathways : KEGGInsulin signaling pathway   
NDEx NetworkRHOQ
Atlas of Cancer Signalling NetworkRHOQ
Wikipedia pathwaysRHOQ
Orthology - Evolution
OrthoDB23433
GeneTree (enSembl)ENSG00000119729
Phylogenetic Trees/Animal Genes : TreeFamRHOQ
HOVERGENP17081
HOGENOMP17081
Homologs : HomoloGeneRHOQ
Homology/Alignments : Family Browser (UCSC)RHOQ
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRHOQ [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RHOQ
dbVarRHOQ
ClinVarRHOQ
1000_GenomesRHOQ 
Exome Variant ServerRHOQ
ExAC (Exome Aggregation Consortium)RHOQ (select the gene name)
Genetic variants : HAPMAP23433
Genomic Variants (DGV)RHOQ [DGVbeta]
DECIPHERRHOQ [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRHOQ 
Mutations
ICGC Data PortalRHOQ 
TCGA Data PortalRHOQ 
Broad Tumor PortalRHOQ
OASIS PortalRHOQ [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRHOQ  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRHOQ
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RHOQ
DgiDB (Drug Gene Interaction Database)RHOQ
DoCM (Curated mutations)RHOQ (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RHOQ (select a term)
intoGenRHOQ
Cancer3DRHOQ(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605857   
Orphanet
MedgenRHOQ
Genetic Testing Registry RHOQ
NextProtP17081 [Medical]
TSGene23433
GENETestsRHOQ
Target ValidationRHOQ
Huge Navigator RHOQ [HugePedia]
snp3D : Map Gene to Disease23433
BioCentury BCIQRHOQ
ClinGenRHOQ
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23433
Chemical/Pharm GKB GenePA134904280
Clinical trialRHOQ
Miscellaneous
canSAR (ICR)RHOQ (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRHOQ
EVEXRHOQ
GoPubMedRHOQ
iHOPRHOQ
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:53:15 CEST 2017

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