Atlas of Genetics and Cytogenetics in Oncology and Haematology


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RHOU (ras homolog family member U)

Identity

Alias_namesARHU
ras homolog gene family
Alias_symbol (synonym)WRCH-1
DJ646B12.2
FLJ10616
WRCH1
CDC42L1
hG28K
fJ646B12.2
Other aliasG28K
HGNC (Hugo) RHOU
LocusID (NCBI) 58480
Atlas_Id 45794
Location 1q42.13  [Link to chromosome band 1q42]
Location_base_pair Starts at 228870824 and ends at 228882416 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
FLNA (Xq28) / RHOU (1q42.13)MAPK7 (17p11.2) / RHOU (1q42.13)NCOR1 (17p12) / RHOU (1q42.13)
RHOU (1q42.13) / RHOU (1q42.13)NCOR1 17p12 / RHOU 1q42.13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RHOU   17794
Cards
Entrez_Gene (NCBI)RHOU  58480  ras homolog family member U
AliasesARHU; CDC42L1; G28K; WRCH1; 
hG28K
GeneCards (Weizmann)RHOU
Ensembl hg19 (Hinxton)ENSG00000116574 [Gene_View]  chr1:228870824-228882416 [Contig_View]  RHOU [Vega]
Ensembl hg38 (Hinxton)ENSG00000116574 [Gene_View]  chr1:228870824-228882416 [Contig_View]  RHOU [Vega]
ICGC DataPortalENSG00000116574
TCGA cBioPortalRHOU
AceView (NCBI)RHOU
Genatlas (Paris)RHOU
WikiGenes58480
SOURCE (Princeton)RHOU
Genetics Home Reference (NIH)RHOU
Genomic and cartography
GoldenPath hg19 (UCSC)RHOU  -     chr1:228870824-228882416 +  1q42.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RHOU  -     1q42.13   [Description]    (hg38-Dec_2013)
EnsemblRHOU - 1q42.13 [CytoView hg19]  RHOU - 1q42.13 [CytoView hg38]
Mapping of homologs : NCBIRHOU [Mapview hg19]  RHOU [Mapview hg38]
OMIM606366   
Gene and transcription
Genbank (Entrez)AB051826 AB074878 AB209511 AF211836 AF251701
RefSeq transcript (Entrez)NM_021205
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_167186 NW_004929294
Consensus coding sequences : CCDS (NCBI)RHOU
Cluster EST : UnigeneHs.647774 [ NCBI ]
CGAP (NCI)Hs.647774
Alternative Splicing GalleryENSG00000116574
Gene ExpressionRHOU [ NCBI-GEO ]   RHOU [ EBI - ARRAY_EXPRESS ]   RHOU [ SEEK ]   RHOU [ MEM ]
Gene Expression Viewer (FireBrowse)RHOU [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)58480
GTEX Portal (Tissue expression)RHOU
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7L0Q8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7L0Q8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7L0Q8
Splice isoforms : SwissVarQ7L0Q8
PhosPhoSitePlusQ7L0Q8
Domaine pattern : Prosite (Expaxy)RHO (PS51420)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase    Small_GTPase_Rho   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Domain families : Smart (EMBL)RHO (SM00174)  
Conserved Domain (NCBI)RHOU
DMDM Disease mutations58480
Blocks (Seattle)RHOU
PDB (SRS)2Q3H   
PDB (PDBSum)2Q3H   
PDB (IMB)2Q3H   
PDB (RSDB)2Q3H   
Structural Biology KnowledgeBase2Q3H   
SCOP (Structural Classification of Proteins)2Q3H   
CATH (Classification of proteins structures)2Q3H   
SuperfamilyQ7L0Q8
Human Protein AtlasENSG00000116574
Peptide AtlasQ7L0Q8
HPRD06965
IPIIPI00009644   IPI00889079   
Protein Interaction databases
DIP (DOE-UCLA)Q7L0Q8
IntAct (EBI)Q7L0Q8
FunCoupENSG00000116574
BioGRIDRHOU
STRING (EMBL)RHOU
ZODIACRHOU
Ontologies - Pathways
QuickGOQ7L0Q8
Ontology : AmiGOG1/S transition of mitotic cell cycle  Golgi membrane  podosome  GTPase activity  protein binding  GTP binding  cytosol  plasma membrane  focal adhesion  intracellular protein transport  nucleocytoplasmic transport  cytoskeleton organization  metabolic process  regulation of cell shape  Rac protein signal transduction  actin cytoskeleton organization  cell projection  metal ion binding  regulation of small GTPase mediated signal transduction  positive regulation of protein targeting to mitochondrion  
Ontology : EGO-EBIG1/S transition of mitotic cell cycle  Golgi membrane  podosome  GTPase activity  protein binding  GTP binding  cytosol  plasma membrane  focal adhesion  intracellular protein transport  nucleocytoplasmic transport  cytoskeleton organization  metabolic process  regulation of cell shape  Rac protein signal transduction  actin cytoskeleton organization  cell projection  metal ion binding  regulation of small GTPase mediated signal transduction  positive regulation of protein targeting to mitochondrion  
NDEx NetworkRHOU
Atlas of Cancer Signalling NetworkRHOU
Wikipedia pathwaysRHOU
Orthology - Evolution
OrthoDB58480
GeneTree (enSembl)ENSG00000116574
Phylogenetic Trees/Animal Genes : TreeFamRHOU
HOVERGENQ7L0Q8
HOGENOMQ7L0Q8
Homologs : HomoloGeneRHOU
Homology/Alignments : Family Browser (UCSC)RHOU
Gene fusions - Rearrangements
Fusion: TCGANCOR1 17p12 RHOU 1q42.13 THCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRHOU [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RHOU
dbVarRHOU
ClinVarRHOU
1000_GenomesRHOU 
Exome Variant ServerRHOU
ExAC (Exome Aggregation Consortium)RHOU (select the gene name)
Genetic variants : HAPMAP58480
Genomic Variants (DGV)RHOU [DGVbeta]
DECIPHER (Syndromes)1:228870824-228882416  ENSG00000116574
CONAN: Copy Number AnalysisRHOU 
Mutations
ICGC Data PortalRHOU 
TCGA Data PortalRHOU 
Broad Tumor PortalRHOU
OASIS PortalRHOU [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRHOU  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRHOU
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RHOU
DgiDB (Drug Gene Interaction Database)RHOU
DoCM (Curated mutations)RHOU (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RHOU (select a term)
intoGenRHOU
Cancer3DRHOU(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606366   
Orphanet
MedgenRHOU
Genetic Testing Registry RHOU
NextProtQ7L0Q8 [Medical]
TSGene58480
GENETestsRHOU
Huge Navigator RHOU [HugePedia]
snp3D : Map Gene to Disease58480
BioCentury BCIQRHOU
ClinGenRHOU
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD58480
Chemical/Pharm GKB GenePA38246
Clinical trialRHOU
Miscellaneous
canSAR (ICR)RHOU (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRHOU
EVEXRHOU
GoPubMedRHOU
iHOPRHOU
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:17:26 CEST 2017

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