RIC1 (RIC1 homolog, RAB6A GEF complex partner 1)

2014-07-01  

Identity

HGNC
LOCATION
9p24.1
LOCUSID
ALIAS
CATIFA,CIP150,KIAA1432,bA207C16.1
FUSION GENES

Other Information

Locus ID:

NCBI: 57589
MIM: 610354
HGNC: 17686
Ensembl: ENSG00000107036

Variants:

dbSNP: 57589
ClinVar: 57589
TCGA: ENSG00000107036
COSMIC: RIC1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000107036ENST00000251879Q4ADV7
ENSG00000107036ENST00000414202Q4ADV7
ENSG00000107036ENST00000418622Q4ADV7
ENSG00000107036ENST00000490816H0YFD4
ENSG00000107036ENST00000545243H0YGC4
ENSG00000107036ENST00000545641H0YFN7

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Retrograde transport at the Trans-Golgi-NetworkREACTOMER-HSA-6811440
Intra-Golgi trafficREACTOMER-HSA-6811438
RAB GEFs exchange GTP for GDP on RABsREACTOMER-HSA-8876198

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
237164742013Genome-wide identification of genes with amplification and/or fusion in small cell lung cancer.49
161120822005Molecular cloning and functional analysis of a novel Cx43 partner protein CIP150.11
319327962020Phenome-based approach identifies RIC1-linked Mendelian syndrome through zebrafish models, biobank associations and clinical studies.2

Citation

Dessen P

RIC1 (RIC1 homolog, RAB6A GEF complex partner 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-07-01

Online version: http://atlasgeneticsoncology.org/gene/54085/ric1