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RIF1 (replication timing regulatory factor 1)

Identity

Alias_namesRAP1 interacting factor homolog (yeast)
Alias_symbol (synonym)FLJ12870
FLJ10599
Other alias-
HGNC (Hugo) RIF1
LocusID (NCBI) 55183
Atlas_Id 51082
Location 2q23.3  [Link to chromosome band 2q23]
Location_base_pair Starts at 152266397 and ends at 152333860 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
FAM49A (2p24.2) / RIF1 (2q23.3)RIF1 (2q23.3) / IFT80 (3q25.33)RIF1 (2q23.3) / LYPD6 (2q23.2)
RIF1 (2q23.3) / PKD1L1 (7p12.3)RIF1 (2q23.3) / RIF1 (2q23.3)TSNARE1 (8q24.3) / RIF1 (2q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RIF1   23207
Cards
Entrez_Gene (NCBI)RIF1  55183  replication timing regulatory factor 1
Aliases
GeneCards (Weizmann)RIF1
Ensembl hg19 (Hinxton)ENSG00000080345 [Gene_View]  chr2:152266397-152333860 [Contig_View]  RIF1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000080345 [Gene_View]  chr2:152266397-152333860 [Contig_View]  RIF1 [Vega]
ICGC DataPortalENSG00000080345
TCGA cBioPortalRIF1
AceView (NCBI)RIF1
Genatlas (Paris)RIF1
WikiGenes55183
SOURCE (Princeton)RIF1
Genetics Home Reference (NIH)RIF1
Genomic and cartography
GoldenPath hg19 (UCSC)RIF1  -     chr2:152266397-152333860 +  2q23.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RIF1  -     2q23.3   [Description]    (hg38-Dec_2013)
EnsemblRIF1 - 2q23.3 [CytoView hg19]  RIF1 - 2q23.3 [CytoView hg38]
Mapping of homologs : NCBIRIF1 [Mapview hg19]  RIF1 [Mapview hg38]
OMIM608952   
Gene and transcription
Genbank (Entrez)AK000323 AK001461 AK022932 AK024033 AK074349
RefSeq transcript (Entrez)NM_001177663 NM_001177664 NM_001177665 NM_018151
RefSeq genomic (Entrez)NC_000002 NC_018913 NG_017162 NT_005403 NW_004929305
Consensus coding sequences : CCDS (NCBI)RIF1
Cluster EST : UnigeneHs.735592 [ NCBI ]
CGAP (NCI)Hs.735592
Alternative Splicing GalleryENSG00000080345
Gene ExpressionRIF1 [ NCBI-GEO ]   RIF1 [ EBI - ARRAY_EXPRESS ]   RIF1 [ SEEK ]   RIF1 [ MEM ]
Gene Expression Viewer (FireBrowse)RIF1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55183
GTEX Portal (Tissue expression)RIF1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5UIP0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5UIP0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5UIP0
Splice isoforms : SwissVarQ5UIP0
PhosPhoSitePlusQ5UIP0
Domains : Interpro (EBI)ARM-like    ARM-type_fold    Rif1    Rif1_N   
Domain families : Pfam (Sanger)Rif1_N (PF12231)   
Domain families : Pfam (NCBI)pfam12231   
Conserved Domain (NCBI)RIF1
DMDM Disease mutations55183
Blocks (Seattle)RIF1
SuperfamilyQ5UIP0
Human Protein AtlasENSG00000080345
Peptide AtlasQ5UIP0
HPRD10603
IPIIPI00293845   IPI00375454   IPI00964181   IPI00910844   IPI00927193   
Protein Interaction databases
DIP (DOE-UCLA)Q5UIP0
IntAct (EBI)Q5UIP0
FunCoupENSG00000080345
BioGRIDRIF1
STRING (EMBL)RIF1
ZODIACRIF1
Ontologies - Pathways
QuickGOQ5UIP0
Ontology : AmiGOchromosome, telomeric region  female pronucleus  male pronucleus  nucleus  nucleoplasm  cytoplasm  spindle  plasma membrane  double-strand break repair via nonhomologous end joining  cell cycle  stem cell population maintenance  positive regulation of double-strand break repair via nonhomologous end joining  
Ontology : EGO-EBIchromosome, telomeric region  female pronucleus  male pronucleus  nucleus  nucleoplasm  cytoplasm  spindle  plasma membrane  double-strand break repair via nonhomologous end joining  cell cycle  stem cell population maintenance  positive regulation of double-strand break repair via nonhomologous end joining  
NDEx NetworkRIF1
Atlas of Cancer Signalling NetworkRIF1
Wikipedia pathwaysRIF1
Orthology - Evolution
OrthoDB55183
GeneTree (enSembl)ENSG00000080345
Phylogenetic Trees/Animal Genes : TreeFamRIF1
HOVERGENQ5UIP0
HOGENOMQ5UIP0
Homologs : HomoloGeneRIF1
Homology/Alignments : Family Browser (UCSC)RIF1
Gene fusions - Rearrangements
Fusion : MitelmanFAM49A/RIF1 [2p24.2/2q23.3]  [t(2;2)(p24;q23)]  
Fusion : MitelmanRIF1/PKD1L1 [2q23.3/7p12.3]  [t(2;7)(q23;p12)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRIF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RIF1
dbVarRIF1
ClinVarRIF1
1000_GenomesRIF1 
Exome Variant ServerRIF1
ExAC (Exome Aggregation Consortium)RIF1 (select the gene name)
Genetic variants : HAPMAP55183
Genomic Variants (DGV)RIF1 [DGVbeta]
DECIPHER (Syndromes)2:152266397-152333860  ENSG00000080345
CONAN: Copy Number AnalysisRIF1 
Mutations
ICGC Data PortalRIF1 
TCGA Data PortalRIF1 
Broad Tumor PortalRIF1
OASIS PortalRIF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRIF1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRIF1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RIF1
DgiDB (Drug Gene Interaction Database)RIF1
DoCM (Curated mutations)RIF1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RIF1 (select a term)
intoGenRIF1
Cancer3DRIF1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608952   
Orphanet
MedgenRIF1
Genetic Testing Registry RIF1
NextProtQ5UIP0 [Medical]
TSGene55183
GENETestsRIF1
Huge Navigator RIF1 [HugePedia]
snp3D : Map Gene to Disease55183
BioCentury BCIQRIF1
ClinGenRIF1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55183
Chemical/Pharm GKB GenePA134933858
Clinical trialRIF1
Miscellaneous
canSAR (ICR)RIF1 (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRIF1
EVEXRIF1
GoPubMedRIF1
iHOPRIF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:17:28 CEST 2017

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