Atlas of Genetics and Cytogenetics in Oncology and Haematology


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RIMS1 (regulating synaptic membrane exocytosis 1)

Identity

Alias_namesRAB3IP2
CORD7
RAB3 interacting protein 2
Alias_symbol (synonym)RIM
KIAA0340
RIM1
Other alias
HGNC (Hugo) RIMS1
LocusID (NCBI) 22999
Atlas_Id 53037
Location 6q13  [Link to chromosome band 6q13]
Location_base_pair Starts at 71886703 and ends at 72403143 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HTN3 (4q13.3) / RIMS1 (6q13)OLFM3 (1p21.1) / RIMS1 (6q13)RIMS1 (6q13) / RIMS1 (6q13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RIMS1   17282
Cards
Entrez_Gene (NCBI)RIMS1  22999  regulating synaptic membrane exocytosis 1
AliasesCORD7; RAB3IP2; RIM; RIM1
GeneCards (Weizmann)RIMS1
Ensembl hg19 (Hinxton)ENSG00000079841 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000079841 [Gene_View]  ENSG00000079841 [Sequence]  chr6:71886703-72403143 [Contig_View]  RIMS1 [Vega]
ICGC DataPortalENSG00000079841
TCGA cBioPortalRIMS1
AceView (NCBI)RIMS1
Genatlas (Paris)RIMS1
WikiGenes22999
SOURCE (Princeton)RIMS1
Genetics Home Reference (NIH)RIMS1
Genomic and cartography
GoldenPath hg38 (UCSC)RIMS1  -     chr6:71886703-72403143 +  6q13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RIMS1  -     6q13   [Description]    (hg19-Feb_2009)
EnsemblRIMS1 - 6q13 [CytoView hg19]  RIMS1 - 6q13 [CytoView hg38]
Mapping of homologs : NCBIRIMS1 [Mapview hg19]  RIMS1 [Mapview hg38]
OMIM603649   606629   
Gene and transcription
Genbank (Entrez)AB002338 AB045726 AB051866 AF263305 AF263306
RefSeq transcript (Entrez)NM_001168407 NM_001168408 NM_001168409 NM_001168410 NM_001168411 NM_001350411 NM_001350412 NM_001350413 NM_001350414 NM_001350415 NM_001350416 NM_001350417 NM_001350418 NM_001350419 NM_001350420 NM_001350421 NM_001350422 NM_001350423 NM_001350424 NM_001350425 NM_001350426 NM_001350427 NM_001350428 NM_001350429 NM_001350430 NM_001350431 NM_001350432 NM_001350433 NM_001350434 NM_001350435 NM_001350436 NM_001350437 NM_001350438 NM_001350439 NM_001350440 NM_001350441 NM_001350442 NM_001350443 NM_001350444 NM_001350445 NM_001350446 NM_001350447 NM_001350448 NM_001350449 NM_001350450 NM_001350452 NM_001350454 NM_001350455 NM_001350456 NM_001350457 NM_001350458 NM_001350459 NM_001350460 NM_001350461 NM_001350462 NM_001350463 NM_001350464 NM_001350465 NM_001350466 NM_001350467 NM_001350468 NM_001350469 NM_001350470 NM_001350471 NM_001350472 NM_001350473 NM_001350474 NM_014989
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RIMS1
Cluster EST : UnigeneHs.485729 [ NCBI ]
CGAP (NCI)Hs.485729
Alternative Splicing GalleryENSG00000079841
Gene ExpressionRIMS1 [ NCBI-GEO ]   RIMS1 [ EBI - ARRAY_EXPRESS ]   RIMS1 [ SEEK ]   RIMS1 [ MEM ]
Gene Expression Viewer (FireBrowse)RIMS1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22999
GTEX Portal (Tissue expression)RIMS1
Human Protein AtlasENSG00000079841-RIMS1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86UR5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86UR5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86UR5
Splice isoforms : SwissVarQ86UR5
PhosPhoSitePlusQ86UR5
Domaine pattern : Prosite (Expaxy)C2 (PS50004)    PDZ (PS50106)    RABBD (PS50916)    ZF_FYVE (PS50178)   
Domains : Interpro (EBI)C2_dom    C2_domain_sf    PDZ    PDZ_sf    Rab_BD    RIM1    Znf_FYVE-rel    Znf_FYVE_PHD   
Domain families : Pfam (Sanger)C2 (PF00168)    PDZ (PF00595)   
Domain families : Pfam (NCBI)pfam00168    pfam00595   
Domain families : Smart (EMBL)C2 (SM00239)  PDZ (SM00228)  
Conserved Domain (NCBI)RIMS1
DMDM Disease mutations22999
Blocks (Seattle)RIMS1
PDB (SRS)2CSS   
PDB (PDBSum)2CSS   
PDB (IMB)2CSS   
PDB (RSDB)2CSS   
Structural Biology KnowledgeBase2CSS   
SCOP (Structural Classification of Proteins)2CSS   
CATH (Classification of proteins structures)2CSS   
SuperfamilyQ86UR5
Human Protein Atlas [tissue]ENSG00000079841-RIMS1 [tissue]
Peptide AtlasQ86UR5
HPRD09435
IPIIPI00387015   IPI00848003   IPI00472331   IPI00339392   IPI00387018   IPI00339394   IPI00387019   IPI00339396   IPI00983413   IPI00922597   IPI00973260   IPI00643480   IPI00922667   IPI00978698   IPI01011011   IPI00982435   IPI00954906   IPI00973328   IPI00985079   
Protein Interaction databases
DIP (DOE-UCLA)Q86UR5
IntAct (EBI)Q86UR5
FunCoupENSG00000079841
BioGRIDRIMS1
STRING (EMBL)RIMS1
ZODIACRIMS1
Ontologies - Pathways
QuickGOQ86UR5
Ontology : AmiGORNA binding  protein binding  cytosol  plasma membrane  intracellular protein transport  visual perception  positive regulation of gene expression  synaptic vesicle exocytosis  Rab GTPase binding  Rab GTPase binding  calcium ion regulated exocytosis  cell junction  GTPase regulator activity  regulation of membrane potential  presynaptic membrane  presynaptic membrane  presynaptic membrane  ion channel binding  regulated exocytosis  synapse  metal ion binding  secretion  regulation of neurotransmitter secretion  regulation of synaptic plasticity  presynaptic active zone  cytoskeleton of presynaptic active zone  calcium ion-regulated exocytosis of neurotransmitter  regulation of catalytic activity  positive regulation of synaptic transmission  response to stimulus  membrane fusion  protein-containing complex assembly  positive regulation of inhibitory postsynaptic potential  presynaptic active zone cytoplasmic component  positive regulation of dendrite extension  regulation of synaptic vesicle exocytosis  positive regulation of excitatory postsynaptic potential  
Ontology : EGO-EBIRNA binding  protein binding  cytosol  plasma membrane  intracellular protein transport  visual perception  positive regulation of gene expression  synaptic vesicle exocytosis  Rab GTPase binding  Rab GTPase binding  calcium ion regulated exocytosis  cell junction  GTPase regulator activity  regulation of membrane potential  presynaptic membrane  presynaptic membrane  presynaptic membrane  ion channel binding  regulated exocytosis  synapse  metal ion binding  secretion  regulation of neurotransmitter secretion  regulation of synaptic plasticity  presynaptic active zone  cytoskeleton of presynaptic active zone  calcium ion-regulated exocytosis of neurotransmitter  regulation of catalytic activity  positive regulation of synaptic transmission  response to stimulus  membrane fusion  protein-containing complex assembly  positive regulation of inhibitory postsynaptic potential  presynaptic active zone cytoplasmic component  positive regulation of dendrite extension  regulation of synaptic vesicle exocytosis  positive regulation of excitatory postsynaptic potential  
Pathways : KEGGSynaptic vesicle cycle    Retrograde endocannabinoid signaling   
NDEx NetworkRIMS1
Atlas of Cancer Signalling NetworkRIMS1
Wikipedia pathwaysRIMS1
Orthology - Evolution
OrthoDB22999
GeneTree (enSembl)ENSG00000079841
Phylogenetic Trees/Animal Genes : TreeFamRIMS1
HOVERGENQ86UR5
HOGENOMQ86UR5
Homologs : HomoloGeneRIMS1
Homology/Alignments : Family Browser (UCSC)RIMS1
Gene fusions - Rearrangements
Fusion : QuiverRIMS1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRIMS1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RIMS1
dbVarRIMS1
ClinVarRIMS1
1000_GenomesRIMS1 
Exome Variant ServerRIMS1
ExAC (Exome Aggregation Consortium)ENSG00000079841
GNOMAD BrowserENSG00000079841
Varsome BrowserRIMS1
Genetic variants : HAPMAP22999
Genomic Variants (DGV)RIMS1 [DGVbeta]
DECIPHERRIMS1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRIMS1 
Mutations
ICGC Data PortalRIMS1 
TCGA Data PortalRIMS1 
Broad Tumor PortalRIMS1
OASIS PortalRIMS1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRIMS1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRIMS1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Eye diseases - LOVD
BioMutasearch RIMS1
DgiDB (Drug Gene Interaction Database)RIMS1
DoCM (Curated mutations)RIMS1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RIMS1 (select a term)
intoGenRIMS1
Cancer3DRIMS1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603649    606629   
Orphanet1843   
DisGeNETRIMS1
MedgenRIMS1
Genetic Testing Registry RIMS1
NextProtQ86UR5 [Medical]
TSGene22999
GENETestsRIMS1
Target ValidationRIMS1
Huge Navigator RIMS1 [HugePedia]
snp3D : Map Gene to Disease22999
BioCentury BCIQRIMS1
ClinGenRIMS1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD22999
Chemical/Pharm GKB GenePA38220
Clinical trialRIMS1
Miscellaneous
canSAR (ICR)RIMS1 (select the gene name)
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRIMS1
EVEXRIMS1
GoPubMedRIMS1
iHOPRIMS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:35:38 CET 2018

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