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RIN2 (Ras and Rab interactor 2)

Identity

Alias_symbol (synonym)RASSF4
Other aliasMACS
HGNC (Hugo) RIN2
LocusID (NCBI) 54453
Atlas_Id 43469
Location 20p11.23  [Link to chromosome band 20p11]
Location_base_pair Starts at 19867165 and ends at 19983103 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
KIAA0226L (13q14.13) / RIN2 (20p11.23)RIN2 (20p11.23) / SYT17 (16p12.3)RIN2 (20p11.23) / ZNF479 (7p11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RIN2   18750
Cards
Entrez_Gene (NCBI)RIN2  54453  Ras and Rab interactor 2
AliasesMACS; RASSF4
GeneCards (Weizmann)RIN2
Ensembl hg19 (Hinxton)ENSG00000132669 [Gene_View]  chr20:19867165-19983103 [Contig_View]  RIN2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000132669 [Gene_View]  chr20:19867165-19983103 [Contig_View]  RIN2 [Vega]
ICGC DataPortalENSG00000132669
TCGA cBioPortalRIN2
AceView (NCBI)RIN2
Genatlas (Paris)RIN2
WikiGenes54453
SOURCE (Princeton)RIN2
Genetics Home Reference (NIH)RIN2
Genomic and cartography
GoldenPath hg19 (UCSC)RIN2  -     chr20:19867165-19983103 +  20p11.23   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RIN2  -     20p11.23   [Description]    (hg38-Dec_2013)
EnsemblRIN2 - 20p11.23 [CytoView hg19]  RIN2 - 20p11.23 [CytoView hg38]
Mapping of homologs : NCBIRIN2 [Mapview hg19]  RIN2 [Mapview hg38]
OMIM610222   613075   
Gene and transcription
Genbank (Entrez)AB060339 AI695804 AK026753 AK094884 AL136924
RefSeq transcript (Entrez)NM_001242581 NM_018993
RefSeq genomic (Entrez)NC_000020 NC_018931 NG_016310 NT_011387 NW_004929416
Consensus coding sequences : CCDS (NCBI)RIN2
Cluster EST : UnigeneHs.733605 [ NCBI ]
CGAP (NCI)Hs.733605
Alternative Splicing GalleryENSG00000132669
Gene ExpressionRIN2 [ NCBI-GEO ]   RIN2 [ EBI - ARRAY_EXPRESS ]   RIN2 [ SEEK ]   RIN2 [ MEM ]
Gene Expression Viewer (FireBrowse)RIN2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54453
GTEX Portal (Tissue expression)RIN2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WYP3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WYP3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WYP3
Splice isoforms : SwissVarQ8WYP3
PhosPhoSitePlusQ8WYP3
Domaine pattern : Prosite (Expaxy)RA (PS50200)    SH2 (PS50001)    VPS9 (PS51205)   
Domains : Interpro (EBI)RA_dom    SH2    Ubiquitin-rel_dom    VPS9   
Domain families : Pfam (Sanger)RA (PF00788)    VPS9 (PF02204)   
Domain families : Pfam (NCBI)pfam00788    pfam02204   
Domain families : Smart (EMBL)RA (SM00314)  SH2 (SM00252)  VPS9 (SM00167)  
Conserved Domain (NCBI)RIN2
DMDM Disease mutations54453
Blocks (Seattle)RIN2
SuperfamilyQ8WYP3
Human Protein AtlasENSG00000132669
Peptide AtlasQ8WYP3
HPRD15249
IPIIPI00549715   IPI00103752   IPI00827607   
Protein Interaction databases
DIP (DOE-UCLA)Q8WYP3
IntAct (EBI)Q8WYP3
FunCoupENSG00000132669
BioGRIDRIN2
STRING (EMBL)RIN2
ZODIACRIN2
Ontologies - Pathways
QuickGOQ8WYP3
Ontology : AmiGOGTPase activator activity  cellular_component  cytoplasm  endocytosis  small GTPase mediated signal transduction  Rab guanyl-nucleotide exchange factor activity  GTPase regulator activity  positive regulation of GTPase activity  positive regulation of GTPase activity  regulation of catalytic activity  
Ontology : EGO-EBIGTPase activator activity  cellular_component  cytoplasm  endocytosis  small GTPase mediated signal transduction  Rab guanyl-nucleotide exchange factor activity  GTPase regulator activity  positive regulation of GTPase activity  positive regulation of GTPase activity  regulation of catalytic activity  
NDEx NetworkRIN2
Atlas of Cancer Signalling NetworkRIN2
Wikipedia pathwaysRIN2
Orthology - Evolution
OrthoDB54453
GeneTree (enSembl)ENSG00000132669
Phylogenetic Trees/Animal Genes : TreeFamRIN2
HOVERGENQ8WYP3
HOGENOMQ8WYP3
Homologs : HomoloGeneRIN2
Homology/Alignments : Family Browser (UCSC)RIN2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRIN2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RIN2
dbVarRIN2
ClinVarRIN2
1000_GenomesRIN2 
Exome Variant ServerRIN2
ExAC (Exome Aggregation Consortium)RIN2 (select the gene name)
Genetic variants : HAPMAP54453
Genomic Variants (DGV)RIN2 [DGVbeta]
DECIPHER (Syndromes)20:19867165-19983103  ENSG00000132669
CONAN: Copy Number AnalysisRIN2 
Mutations
ICGC Data PortalRIN2 
TCGA Data PortalRIN2 
Broad Tumor PortalRIN2
OASIS PortalRIN2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRIN2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRIN2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RIN2
DgiDB (Drug Gene Interaction Database)RIN2
DoCM (Curated mutations)RIN2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RIN2 (select a term)
intoGenRIN2
Cancer3DRIN2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610222    613075   
Orphanet18846   
MedgenRIN2
Genetic Testing Registry RIN2
NextProtQ8WYP3 [Medical]
TSGene54453
GENETestsRIN2
Huge Navigator RIN2 [HugePedia]
snp3D : Map Gene to Disease54453
BioCentury BCIQRIN2
ClinGenRIN2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54453
Chemical/Pharm GKB GenePA38672
Clinical trialRIN2
Miscellaneous
canSAR (ICR)RIN2 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRIN2
EVEXRIN2
GoPubMedRIN2
iHOPRIN2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:17:29 CEST 2017

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